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Receptor for somatostatin with higher affinity for somatostatin-14 than -28. Zusätzlich bieten wir Ihnen SSTR1 Antikörper (126) und SSTR1 Kits (26) und viele weitere Produktgruppen zu diesem Protein an.
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Human SSTR1 Protein expressed in Wheat germ - ABIN1330528
Breitkopf, Lo, Leung, Wang, Yu, Carr, Zloty, Cowan, Shapiro, McElwee: Somatostatin expression in human hair follicles and its potential role in immune privilege. in The Journal of investigative dermatology 2013
Data showed that the distribution of somatostatin (zeige SST Proteine) receptor (SSTR (zeige SSTR3 Proteine)) subtypes among the 199 pancreatic neuroendocrine tumors (PNETs) was: SSTR2 (zeige SSTR2 Proteine) (54.8%), SSTR1 (53.3%), SSTR4 (51.8%), SSTR5 (zeige SSTR5 Proteine) (33.7%), and SSTR3 (zeige SSTR3 Proteine) (28.6%).
An immunohistochemical investigation of the expression of somatostatin (zeige SST Proteine) receptor subtypes
Aberrant methylation inactivates somatostatin (zeige SST Proteine) and SSTR1 in head and neck squamous cell carcinoma.
The UMB-7 may prove of great value in the identification of sst1-expressing tumors during routine histopathological examinations. This may open up new routes for diagnostic and therapeutic intervention.
SSTR (zeige SSTR3 Proteine)-PET showed high sensitivity for imaging bone, soft tissue and brain metastases, and particularly in combination with CT had a significant impact on clinical stage and patient management.
Activated/phosphorylated pMAPK 44/42 was detected in 82% of medulloblastomas, all subtypes, and in 62.5% of primitive neuroectodermal tumors with coexpression of SSR1 (zeige SSR1 Proteine) in one third.
Somatostatin (zeige SST Proteine) receptor imaging (SRI (zeige SRI Proteine)) using SPECT or PET as a whole-body imaging technique has become a crucial part of the management of Neuroendocrine tumors
Tumor cells in the tissue samples of the patients diagnosed with advanced-stage hepatocellular carcinoma expressed a high proportion of SSTR1 and SSTR5 (zeige SSTR5 Proteine).
Somatostatin receptor 1 is a novel methylated gene driven by EBV infection in gastric cancer cells and acts as a potential tumour suppressor.
Data demonstrate that cells transfected with SSTR1 or SSTR1/5 negatively regulates EGF (zeige EGF Proteine) mediated effects attributed to the inhibition of EGFR (zeige EGFR Proteine) phosphorylation.
This study showed that reduced expression of the Sstr1 which modulate antidepressant action in hippocampus.
The expression and localization of the three receptors (SSTR3 (zeige SSTR3 Proteine)-SSTR5 (zeige SSTR5 Proteine)) in wild-type (WT), single-knockout (SSTR1 KO) and double-knockout SSTR1/SSTR2 (zeige SSTR2 Proteine) (DKO) mice, are reported.
SSTR1 was expressed in Kolliker's organ on E14, on cochlear duct hair cells & supporting cells on E17 and only on the organ of Corti at birth, increasing & peaking at P14 (zeige PCOLCE Proteine) but dropping off at P21.
SSTR1-like immunoreactivity increases in hypothalamus except in paraventricular nucleus of ApoD (zeige APOD Proteine)(-/-) mice.
SST (zeige SST Proteine) and SSTRs might play an important role in regulation of neurodegeneration
Data suggest an important role for the brain somatostatin receptor 1 subtype in the modulation of the gastrointestinal response to activation of brain CRF (zeige CRH Proteine) pathways.
The effect of sst2 (zeige SSTR2 Proteine) receptor knockout on sst1 receptor mRNA localization and binding sites throughout the brain has been determined.
The localization of somatostatin (zeige SST Proteine) to retinal amacrine cells, together with the expression of somatostatin (zeige SST Proteine) receptors in amacrine, bipolar and horizontal cells suggests that somatostatin (zeige SST Proteine) acts at multiple levels of retinal circuitry.
Brain somatostatin (zeige SST Proteine) receptors 1,2,4 and 5 are up-regulated in somatostatin (zeige SST Proteine)-deficient mice, and SSTR3 (zeige SSTR3 Proteine) is down-regulated.
sst1 receptor loss causes a significant increase in retinal levels of somatostatin-14 (zeige SST Proteine) (SRIF (zeige SST Proteine)) whereas it does not affect SRIF (zeige SST Proteine) messenger RNA, indicating that sst1 receptors play a role in limiting retinal SRIF (zeige SST Proteine) at the post-transcriptional level.
5-HT(1A (zeige HTR1A Proteine)), SST (zeige SST Proteine)(1), and SST (zeige SST Proteine)(2) receptors mediate nonadrenergic IPSPs in the noncholinergic (VIP (zeige Vip Proteine)) secretomotor neurons of the submucous plexus of the guinea pig ileum.
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
somatostatin receptor type 1
, somatostatin receptor 1
, Somatostatin receptor subtype 1