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SCGB1A1 encodes a member of the secretoglobin family of small secreted proteins. Zusätzlich bieten wir Ihnen SCGB1A1 Antikörper (141) und SCGB1A1 Kits (80) und viele weitere Produktgruppen zu diesem Protein an.
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Our data suggest that rCC16 suppresses LPS (zeige IRF6 Proteine)-mediated inflammatory mediator TNF-alpha (zeige TNF Proteine), IL-6 (zeige IL6 Proteine), and IL-8 (zeige IL8 Proteine) production by inactivating NF-kappaB (zeige NFKB1 Proteine) and p38 MAPK (zeige MAPK14 Proteine) but not AP-1 (zeige FOSB Proteine) in RAW264.7 cells.
Lung-specific (CC-16) and novel (RelB (zeige RELB Proteine)) biomarkers are associated with systemic cardiovascular changes over time. CC-16 can predict subsequent exacerbations in subjects with severe COPD (zeige ARCN1 Proteine) and may be an important biomarker of pulmonary and systemic stress in COPD (zeige ARCN1 Proteine).
Smokers and COPD patients had reduced airway CC16 immunostaining that decreased with in (zeige NFKB1 Proteine)creasing COPD severity.
the uteroglobin G38A gene polymorphism was not associated with IgAN risk
In chromium-exposed workers, blood levels of CC16, and CC16/SP-D (zeige SFTPD Proteine) were lower than in controls. Positive relationships were shown between CC16 or CC16/SP-D (zeige SFTPD Proteine) and indicators of lung function.
role of Secretoglobin (zeige SCGB3A1 Proteine) 1A1 (zeige SLC45A2 Proteine) and 1A1A in neutrophil reactive oxygen species production, phagocytosis and extracellular trap formation [secretoglobin (zeige SCGB3A1 Proteine) 1A1 (zeige SLC45A2 Proteine)][secretoglobi 1A1A]
In the oviduct tissue, a decrease in the level of SCGB1A1 mRNA expression was observed from 144 h post-ovulation.In the endometrium a significant decline in the level of SCGB1A1 mRNA expression from 16 to 144 h post-ovulation induction was observed.
the present results demonstrate that rCC16 has therapeutic effects on COPD by downregulating proinflammatory factors via the NFkappaB pathway.
This study extends the function of the Scgb1a1-expressing epithelial cell population as a major mediator of the antiviral response. It
CC16 protects lungs from cigarette smoke (CS)-induced injury by reducing lung NF-kappaB (zeige NFKB1 Proteine) activation. CS-induced airway CC16 deficiency increases CS-induced pulmonary inflammation and injury and likely contributes to the pathogenesis of COPD (zeige ARCN1 Proteine).
Suggest role for Scgb1a1(+) cells in the generation of p63 (zeige CKAP4 Proteine)(+) cells in the damaged lung parenchyma.
Serum CC-16 is associated with disease progression in chronic obstructive pulmonary disease (COPD (zeige ARCN1 Proteine)). However, the absence of CC-16 does not appear to modify the risk of cigarette-related COPD (zeige ARCN1 Proteine) in mice.
the role of clara cells and clara cell secretory protein in lung radiation injury exacerbated by viral infection
AAV2/9-CC10 vector virus guaranteed sufficient CC10 expression and had an anti-inflammatory effect in asthmatic mice.
Claudin-3 (zeige CLDN3 Proteine) and Clara cell 10 kDa protein were identified as possible markers of early tobacco smoke-induced epithelial injury along alveolar ducts.
Scgb1a1-expressing cells, most likely Clara cells, are a major cell type that gives rise to alveolar type I and II cells during the regeneration of alveolar epithelia in response to severe pulmonary damage in mice.
These results indicate that CC10 gene transfer may inhibit airway inflammation through suppressing the activation of NF-kappaB (zeige NFKB1 Proteine).
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
, clara cell phospholipid-binding protein
, clara cells 10 kDa secretory protein
, urinary protein 1
, urine protein 1
, secretoglobin family 1A member 1
, PCB-binding protein
, clara cell 17 kDa protein
, clara cell secretory protein
, Uteroglobin (Clara cell secretory protein)
, secretoglobin, family 1A, member 1 (uteroglobin)