anti-Ring Finger Protein 43 (RNF43) Antikörper

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]\; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM, Dec 2008].. Zusätzlich bieten wir Ihnen RNF43 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF43 54894 Q68DV7
RNF43 207742 Q5NCP0
RNF43 303412  
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Showing 10 out of 34 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RNF43 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  MCF7 cell lysate RNF43 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Human Maus Unkonjugiert CyTOF, FACS Detection of RNF43 in HEK293 Human Cell Line Transfected with Human RNF43 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human RNF43 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human RNF43 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 9 bis 11 Tage
$284.76
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Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: RNF43 Antibody [NBP1-85018] - Staining of human kidney shows strong nuclear positivity in cells in tubules. Immunohistochemistry-Paraffin: RNF43 Antibody  - Staining of human duodenum shows moderate nuclear positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-RNF43 Polyclonal Antibody, Unconjugated (ABIN721600) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse testis labeled with Anti RNF43 Polyclonal Antibody, Unconjugated (ABIN721600) followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western Blot at 1:2000 dilution + A549 whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
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Human Maus Alexa Fluor 488 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$374.03
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Human Maus Alexa Fluor 700 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$374.03
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Human Maus Alexa Fluor 350 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$374.03
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Human Maus Alexa Fluor 750 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$374.03
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Am meisten referenzierte anti-RNF43 Antikörper

  1. Cow (Bovine) Polyclonal RNF43 Primary Antibody für WB - ABIN2774743 : Sugiura, Yamaguchi, Miyamoto: A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95. in Experimental cell research 2008 (PubMed)

Weitere Antikörper gegen RNF43 Interaktionspartner

Human Ring Finger Protein 43 (RNF43) Interaktionspartner

  1. The proportion of mutant RNF43 in Lynch syndrome related colorectal cancers is significantly lower than the previously reported mutation rate found in sporadic microsatellite unstable colorectal cancers. These findings identify further genetic differences between sporadic and hereditary colorectal cancers.

  2. results establish that RSPO2, without the LGR4/5/6 receptors, serves as a direct antagonistic ligand to RNF43 and ZNRF3, which together constitute a master switch that governs limb specification; these findings have direct implications for regenerative medicine and WNT-associated cancers

  3. Data suggest that inactivation of RNF43 and ZNRF3 is important in serrated tumorigenesis and has identified a potential therapeutic strategy for this cancer subtype.

  4. Chimeric transcript resulting from the fusion of RNF43 and SUPT4H1 was found to occur frequently in primary colorectal carcinoma.

  5. RNF43 mutation constitutes an important mutated driver gene for the Serrated Neoplasia pathway in both the sporadic and familial Polyposis settings.

  6. RNF43 is down-regulated in intrahepatic cholangiocarcinoma and may play a crucial role during development of ICC.

  7. The finding of RNF43 mutation in sessile serrated adenoma and traditional serrated adenoma, but not in tubulovillous/villous adenoma, indicated that RNF43 mutation is an early and specific molecular aberration in the serrated colorectal carcinoma pathway.

  8. Mutations and downregulation of RNF43 may play a critical role in the transition from adenoma to carcinoma.

  9. PTPRK-RSPO3 fusions and RNF43 mutations were found to be characteristic genetic features of traditional serrated adenomas (TSAs).

  10. our study exhibited the expression patterns and correlation of RNF43 and p53 pathway proteins involved in cell cycling

  11. Authors also identified ring finger 43 (RNF43), an inhibitor of Wnt/beta-catenin signaling, as a target of miR-550a-5p.

  12. RNF43 inhibits the Wnt pathway downstream of oncogenic mutations that activate the pathway.

  13. RNF43 might act as a tumor suppressor in gastric carcinoma and might be a potential indicator for the clinical assessment of gastric cancer prognosis

  14. RNF43 gene harbored not only exceedingly high mutations but also mutational intratumoral heterogeneity, which together might play a role in tumorigenesis of gastric and colorectal cancers.

  15. The nucleoprotein of influenza A virus targets RNF43 to modulate p53 ubiquitination levels and hence causes p53 stabilization which is conducive to an enhanced apoptosis level in the host cells.

  16. we found that the decreased expression of RNF43 in glioma was associated with poor prognosis by the Kaplan-Meier survival analysis. Importantly, multivariate analysis suggested RN43 as an independent predictor of overall survival.

  17. These results indicate that RNF43 mutation might cause downregulation of the expression of ring finger protein 43 and play a crucial role during development of intraductal papillary mucinous neoplasm of the pancreas.

  18. Data indicate Dishevelled (DVL) as a dual function adaptor to recruit negative regulators ZNRF3/RNF43 to Wnt receptors to ensure proper control of pathway activity.

  19. Missense mutations of RNF43 change their localization from the endosome to the endoplasmic reticulum.

  20. RNF43 is one of the most commonly mutated genes in colorectal and endometrial cancers

Mouse (Murine) Ring Finger Protein 43 (RNF43) Interaktionspartner

  1. RSPO-LGR4/5-ZNRF3/RNF43 module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.

  2. RNF43 and ZNRF3 reduce Wnt signals by selectively ubiquitinating frizzled receptors, thereby targeting these Wnt receptors for degradation

RNF43 Antigen-Profil

Protein Überblick

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004

Genbezeichner und Symbole assoziert mit RNF43

  • ring finger protein 43 (RNF43) Antikörper
  • ring finger protein 43 (Rnf43) Antikörper
  • 4732452J19Rik Antikörper
  • RGD1305204 Antikörper
  • RNF124 Antikörper
  • URCC Antikörper

Bezeichner auf Proteinebene für RNF43

E3 ubiquitin-protein ligase RNF43 , RING finger protein 43

GENE ID SPEZIES
100057001 Equus caballus
54894 Homo sapiens
491114 Canis lupus familiaris
784035 Bos taurus
207742 Mus musculus
303412 Rattus norvegicus
Ausgewählte Anbieter für anti-RNF43 (RNF43) Antikörper
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