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The protein encoded by RNF138 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Zusätzlich bieten wir Ihnen Ring Finger Protein 138 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Rnf138 deficiency promotes the apoptosis of spermatogenic cells.
This study identify RNF138 as the E3 ubiquitin ligase (zeige MUL1 Antikörper) promoting EA2 (zeige CACNA1A Antikörper)-associated aberrant degradation of human CaV2.1 (zeige CACNA1A Antikörper) protein.
Rad51d mediated by E3 Ligase Rnf138 has a role in the homologous recombination repair pathway
RNF138 is a newly identified regulatory component of the HR mediated DNA repair pathway that has implications toward understanding how ubiquitination modifies the functions of the RAD51 (zeige RAD51 Antikörper) paralog protein complex
Data show that ubiquitin E3 ligase RNF138 regulates Ku80 (zeige XRCC5 Antikörper) antigen ubiquitylation in response to DNA damage.
Data show that ubiquitin E2 enzymes UBE2D1 (zeige UBE2D1 Antikörper)/2/3 and E3 ligase RNF138 accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (zeige RBBP8 Antikörper) protein ubiquitylation and accrual.
The RNF138 gene is highly expressed in glioma tissue and glioma cell lines and plays an important role in glioma cell proliferation, apoptosis, and cell cycle.
NARF functions as a novel ubiquitin-ligase to regulate ubiquitylation and degradation of T cell factor/lymphoid enhancer factor
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
E3 ubiquitin-protein ligase RNF138
, NLK-associated RING finger protein
, Nemo-like kinase-associated RING finger protein
, nemo-like kinase associated ring finger protein
, nemo-like kinase-associated RING finger protein