anti-Ras Association Domain-Containing Protein 6 (RASSF6) Antikörper

RASSF6 encodes a member of the Ras-association domain family (RASSF). Zusätzlich bieten wir Ihnen RASSF6 Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RASSF6 166824 Q6ZTQ3
RASSF6 73246 Q80UQ2
RASSF6 305251 Q4QR82
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Top anti-RASSF6 Antikörper auf antikoerper-online.de

Showing 10 out of 76 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-RASSF6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: NCI-H226 cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334475 (1µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 bis 7 Tage
$429.84
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using RASSF6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Verfügbar
$363.46
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg 11 bis 14 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB ABIN6275449 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 bis 12 Tage
$390.77
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 bis 14 Tage
$727.83
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg 4 bis 8 Tage
$522.50
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cells, using RASSF6 antibody. 100 μL 11 bis 13 Tage
$366.77
Details

Am meisten referenzierte anti-RASSF6 Antikörper

  1. Human Polyclonal RASSF6 Primary Antibody für ELISA, WB - ABIN314334 : Allen, Donninger, Vos, Eckfeld, Hesson, Gordon, Birrer, Latif, Clark: RASSF6 is a novel member of the RASSF family of tumor suppressors. in Oncogene 2007 (PubMed)

Weitere Antikörper gegen RASSF6 Interaktionspartner

Human Ras Association Domain-Containing Protein 6 (RASSF6) Interaktionspartner

  1. RASSF6 increases unphosphorylated pRb and augments the interaction between pRb and E2F1. Moreover, RASSF6 induces TP73 target genes via pRb and E2F1 in a p53-negative background.

  2. RASSF6 functions as a potential tumor suppressor in human breast cancer through activation of Hippo pathway.

  3. RASSF6 is down-regulated and exhibits tumor suppressor activities in hepatocellular carcinoma.

  4. Study reports the interaction of BCL-XL with RASSF6. BCL-XL inhibits the interaction between RASSF6 and MDM2 and suppresses p53 expression. Consequently, BCL-XL antagonizes RASSF6-mediated apoptosis. Thus, the inhibition of RASSF6-mediated apoptosis also underlies the prosurvival role of BCL-XL.

  5. Data suggest that Ras-association domain family protein 6 (RASSF6) may serve as a candidate against tumor growth for sporadic colorectal cancer (sCRC).

  6. RASSF6 and RASSF10 were frequently hypermethylated in the samples at the time of diagnosis of adult acute lymphoblastic leukemia patients

  7. Overexpression or silencing of RASSF6 could partially reverse the effects of the overexpression or repression of miR-181a-5p on GC progress caused by activation of the MAKP pathway in vitro and in vivo.

  8. Results suggest that down-regulation of RASSF2, and RASSF6 is a tumor-specific phenomenon and their inactivation through CpG island methylation may play important roles in gastric cardia carcinogenesis.

  9. Mechanistic investigation shows that RASSF6 triggers p21(Cip1/Waf1) accumulation to induce G 1 cell cycle arrest and promote apoptosis upon exposure to pro-apoptotic agents, and both of these mechanisms appear to be mediated by activated JNK signaling.

  10. RASSF6 expression is an independent biomarker of an unfavorable prognosis in patients with pancreatic ductal adenocarcinoma.

  11. RASSF6 exhibits promoter hypermethylation in metastatic melanoma and inhibits invasion in melanoma cells.RASSF6 exhibits the highest frequency of inactivation in melanoma and in melanoma brain metastases.

  12. downregulation of RASSF6 in highly metastatic nasopharyngeal carcinoma cells contributed to their treatment resistance

  13. RASSF6-induced apoptosis partially depends on p53. RASSF6 binds MDM2 and facilitates its ubiquitination. RASSF6 depletion blocks the increase of p53 in response to UV exposure and up-regulation of p53 target genes.

  14. The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.

  15. Decreased expression of RASSF6 is associated with gastric cancer.

  16. These findings indicate that RASSF6 is implicated in apoptosis in HeLa cells and that it triggers both caspase-dependent and caspase-independent pathways.

  17. Demonstrates properties of a Ras effector and tumor suppressor but exhibits biological properties that are unique and distinct from those of other family members.

  18. Sequencing revealed RASSF6 and RASSF10 were the only RASSF members with a high frequency of leukaemia-specific methylation.

  19. activation of MST2 causes apoptosis through the Hippo pathway, as well as through a RASSF6-mediated pathway

Mouse (Murine) Ras Association Domain-Containing Protein 6 (RASSF6) Interaktionspartner

  1. RASSF6 expression in adipocytes is down-regulated by interaction with macrophages.

  2. Demonstrates properties of a Ras effector and tumor suppressor but exhibits biological properties that are unique and distinct from those of other family members.

RASSF6 Antigen-Profil

Protein Überblick

This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.

Genbezeichner und Symbole assoziert mit RASSF6

  • Ras association domain family member 6 (RASSF6) Antikörper
  • Ras association (RalGDS/AF-6) domain family member 6 (Rassf6) Antikörper
  • Ras association (RalGDS/AF-6) domain family 6 (rassf6) Antikörper
  • Ras association domain family member 6 (Rassf6) Antikörper
  • 1600016B17Rik Antikörper
  • im:7154480 Antikörper
  • si:dz57f23.2 Antikörper
  • zgc:136957 Antikörper

Bezeichner auf Proteinebene für RASSF6

Ras association (RalGDS/AF-6) domain family 6 , putative RAS binding protein , ras association domain-containing protein 6

GENE ID SPEZIES
166824 Homo sapiens
73246 Mus musculus
751594 Danio rerio
305251 Rattus norvegicus
Ausgewählte Anbieter für anti-RASSF6 (RASSF6) Antikörper
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