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May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1 (By similarity). Zusätzlich bieten wir Ihnen RYBP Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal RYBP Primary Antibody für IP - ABIN4351512
Holdt, Hoffmann, Sass, Langenberger, Scholz, Krohn, Finstermeier, Stahringer, Wilfert, Beutner, Gielen, Schuler, Gäbel, Bergert, Bechmann, Stadler, Thiery, Teupser: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. in PLoS genetics 2013
This study revealed the molecular mechanism responsible for RYBP nuclear translocation.
this is the first study to show the correlation between RYBP polymorphisms with the risk and prognosis of HCC (zeige FAM126A Antikörper). We found that the RYBP SNP, rs2118593 can be a new predictor for poor prognosis of HCC (zeige FAM126A Antikörper), providing a scientific basis for improving the treatment and prognosis of HCC (zeige FAM126A Antikörper).
findings support the idea that RYBP may represent a target for cancer therapy and suggest that it may be useful as a prognostic biomarker for HCC (zeige FAM126A Antikörper), either alone or in combination with KLF4 (zeige KLF4 Antikörper) and Sp1 (zeige PSG1 Antikörper)
overexpression of RYBP suppresses breast cancer growth and metastasis both in vitro and in vivo.
RYBP activates FANK1-mediated activator protein 1 (AP-1) signaling pathway which contributes to tumor cell apoptosis.
Results identify a novel YY1 (zeige YY1 Antikörper) ~ miR (zeige MLXIP Antikörper)-9 ~ RYBP axis involved in melanoma tumorigenesis and reinforce the idea that regulatory circuitries involving miRNAs and TFs are prevalent mechanisms.
RYBP has a role in survival of patients with hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) and responsiveness to chemotherapy
Polymorphisms in RYBP and AOAH (zeige AOAH Antikörper) genes are associated with chronic rhinosinusitis in a Chinese population.
YEAF1/RYBP and YAF-2 (zeige YAF2 Antikörper) are functionally distinct members of a cofactor family for the YY1 (zeige YY1 Antikörper) and E4TF1/hGABP transcription factors.
interacts specifically with the E2F2 and E2F3 family members, dependent on the marked box domain in these proteins
Here, the authors discover that the histone H2AK119 E3 ubiquitin ligase (zeige MUL1 Antikörper) activity of Polycomb (zeige CBX2 Antikörper) repressive complex 1 (PRC1 (zeige PRC1 Antikörper)) is defined by the composition of its catalytic subunits and is highly regulated by RYBP/YAF2 (zeige YAF2 Antikörper)-dependent stimulation.
these results reveal important functions of DDX5 (zeige DDX5 Antikörper) in regulating reprogramming and highlight the importance of a Ddx5 (zeige DDX5 Antikörper)-miR125b-Rybp axis in controlling cell fate.
These results show that a sustained regulation of the B-1-to-B (zeige TDO2 Antikörper)-2 B cell lineage switch is needed throughout adult life and that RYBP plays an important role in keeping B-2 dominance, most likely independently of its Polycomb (zeige CBX2 Antikörper) affiliation.
The data provide evidence for a previously unrecognized function of Rybp in heart development and point out the importance of germ cell lineage gene silencing during somatic differentiation.
Although the genomic localization of the Cbx7 (zeige CBX7 Antikörper)- and RYBP-containing PRC1 (zeige PRC1 Antikörper) complexes overlaps in certain genes, it can also be mutually exclusive.
identify Rybp as a novel regulator of myogenesis that co-acts with YY1 (zeige YY1 Antikörper) to silence miR (zeige MLXIP Antikörper)-29 and other myogenic loci.
Rybp efficiently represses endogenous retroviruses (murine endogenous retrovirus [MuERV] class) and preimplantation (including zygotic genome activation stage)- and germ line-specific genes.
RYBP-PRC1 (zeige PRC1 Antikörper) is recruited to target loci in mESCs and is also involved in Xist RNA-mediated silencing, the latter suggesting a wider role in Polycomb (zeige CBX2 Antikörper) silencing.
Rybp/DEDAF is required for early postimplantation and for central nervous system development
The Rybp interacting PcG protein Ring1B, a known ubiquitin E3 ligase, promotes Rybp ubiquitination; one target of Rybp's ubiquitin binding domain appears to be ubiquitinated histone H2A
Yaf2 (zeige YAF2 Antikörper) and Rybp can encode opposing functions in the regulation of apoptosis [yaf2 (zeige YAF2 Antikörper)]
May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1 (By similarity).
RING1 and YY1 binding protein
, DED-associated factor
, RING1 and YY1-binding protein
, YY1 and E4TF1 associated factor 1
, YY1 and E4TF1-associated factor 1
, apoptin-associating protein 1
, death effector domain-associated factor
, ring1 interactor RYBP
, Ring1 interactor Rybp
, DED-associated factor A
, RING1 and YY1-binding protein A
, death effector domain-associated factor A