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Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular transport in protein secretion and the endocytosis pathway (Zheng et al., 1998 [PubMed 9512502]).[supplied by OMIM, Feb 2010].. Zusätzlich bieten wir Ihnen RAB33B Antikörper (17) und viele weitere Produktgruppen zu diesem Protein an.
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Rab33 modulates autophagosome formation through interaction with Atg16L (zeige ATG16L1 Proteine)
Here we present three SMC (zeige DYM Proteine) patients with four novel pathogenic variants in RAB33B, including homozygosity for c.211C>T (p.R71*), homozygosity for c.365T>C (p.F122S), and compound heterozygosity for c.48delCGGGGCAG (p.G17Vfs*58) and c.490C>T (p.Q164*).
Arg-24 of Atg16L1 (zeige ATG16L1 Proteine) is crucial for its interaction with Atg5 (zeige ATG5 Proteine) which has implications in the binding of the dimeric complex to Rab33B
Analysis of hepatitis B virus capsid maturation steps revealed that Rab33B and Atg5/12/16L1 are required for proper particle assembly and/or stability.
Ric1-Rgp1 complex is a guanine nucleotide exchange factor (zeige RASGRF1 Proteine) for the late Golgi Rab6A (zeige RAB6A Proteine) GTPase (zeige RACGAP1 Proteine) and an effector of the medial Golgi Rab33B GTPase (zeige RACGAP1 Proteine).
A second autosomal recessive locus for Dyggve-Melchior-Clausen syndrome exists on 4q31.1 and that Rab (zeige HRB Proteine) protein-encoding gene, RAB33B, is the likely disease gene in that locus.
Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular transport in protein secretion and the endocytosis pathway (Zheng et al., 1998
RAB33B, member RAS oncogene family
, ras-related protein Rab-33B
, RAB33B, member of RAS oncogene family