anti-Protein S (Alpha) (PROS1) Antikörper

PROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. Zusätzlich bieten wir Ihnen PROS1 Kits (24) und PROS1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PROS1 5627 P07225
PROS1 19128 Q08761
PROS1 81750  
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Top anti-PROS1 Antikörper auf

Showing 10 out of 102 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PROS1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Muscle Immunohistochemistry with Liver tissue at an antibody concentration of 5µg/ml using anti-PROS1 antibody (ARP56097_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Pros1 Antibody Titration: 1.0 ug/ml Positive Control: Rat Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: Protein S Antibody [NBP1-59165] - Human Liver tissue 5ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Anti-PROS1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959013 concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using protein S (alpha), antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Protein S/PROS1 Antibody [NBP1-31375] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/Immunofluorescence: Protein S/PROS1 Antibody [NBP1-31375] - Analysis of HeLa, using NBP1-31375 at 1:200 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis on human serum using anti- Vitamin K-dependent protein S polyclonal antibody.        100 μL Anmelden zum Anzeigen 13 bis 16 Tage

PROS1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine) ,
Rat (Rattus) ,


Am meisten referenzierte anti-PROS1 Antikörper

  1. Human Polyclonal PROS1 Primary Antibody für IHC, IHC (p) - ABIN4892115 : Ten Kate, Platteel, Mulder, Terpstra, Nicolaes, Reitsma, van der Steege, van der Meer: PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations. in Human mutation 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PROS1 Primary Antibody für IHC, IHC (p) - ABIN4347906 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

Weitere Antikörper gegen PROS1 Interaktionspartner

Human Protein S (Alpha) (PROS1) Interaktionspartner

  1. these results suggest a novel pathogenic role of SPE B that initiates protein S degradation followed by the inhibition of apoptotic cell clearance by macrophages

  2. Developed functional protein S assays that measure both the activated protein C (zeige PROC Antikörper)- and TFPI (zeige TFPI Antikörper)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  3. Taken together, our gain-of-function, loss-of-function analyses suggest that PROS may facilitate cell proliferation and promote castration resistance in human castration-resistant PCa (zeige FLVCR1 Antikörper)-like cells via its apoptosis-regulating property.

  4. we identify PROS1 as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL (zeige AXL Antikörper) expression

  5. The prevalence of PS de fi ciency in the present study was higher than in Western countries and con (zeige DISP1 Antikörper) fi rms the high prevalence of PS de fi ciency in Asian populations

  6. Patients with type 2 diabetes had significantly lower circulating free protein S than healthy control subjects

  7. In the present study, gene analysis of six unrelated Japanese families diagnosed with congenital protein S deficiency identified five missense mutations in the PROS1 gene - c.757C>T (Ala139Val; A139V), c.1346 G>T (Cys449Phe; C449F), c.1352G>A (Arg451Gln; R451Q), c.1424G>T (Cys475Phe; C475F) and c.1574C>T (Ala525Val; A525V) - and one frameshift mutation, c.2135delA (Asp599ThrfsTer13; D599TfsTer13).

  8. The odds ratio of developing idiopathic fatal pulmonary embolism as a variant carrier for PROS1 is 56.4 (95% CI, 5.3-351.1; P = 0.001).

  9. described a novel PROS1 frameshift mutation, c.74dupA, in a hereditary protein S deficiency family. Interestingly, both of the proband and his mother carried the mutation and had a protein S deficiency, however, only the proband suffered a pulmonary embolism while his mother had no history of any thrombosis, suggesting that a triggering event might have been involved in the thrombus formation.

  10. PROS1 may play an important role in the development of glioblastoma multiforme through cellular proliferation, migration and invasion as well as apoptosis.

Cow (Bovine) Protein S (Alpha) (PROS1) Interaktionspartner

  1. Activated protein C (zeige PROC Antikörper)(APC (zeige APC Antikörper)) combined with protein S(PS) had significant antithrombotic effect. APC (zeige APC Antikörper) combined with PS prolonged clotting time. Dependence on APC (zeige APC Antikörper)-cofactor activity of PS for expression of anticoagulant activity by APC (zeige APC Antikörper).

Mouse (Murine) Protein S (Alpha) (PROS1) Interaktionspartner

  1. This study identifies a duple role for PROS1 in stem-cell quiescence and as a pro-neurogenic factor, and highlights a unique segregation of increased stem cell proliferation from enhanced neuronal differentiation.

  2. Mice overexpressing protein S showed significant improvements in blood glucose level, glucose tolerance, insulin (zeige INS Antikörper) sensitivity, and insulin (zeige INS Antikörper) secretion compared with wild-type counterparts. diabetic protein S transgenic mice developed significantly less severe diabetic glomerulosclerosis than controls.

  3. By revealing that neural stem-like cells act within the SVZ neurogenic niche as phagocytes and that the ProS/MerTK (zeige MERTK Antikörper) path represents an endogenous regulatory mechanism for SVZ cell phagocytic activity

  4. Optimal TAM (zeige CCNA1 Antikörper) signaling requires coincident TAM (zeige CCNA1 Antikörper) ligand engagement of both its receptor and the phospholipid phosphatidylserine regulating TAM (zeige CCNA1 Antikörper) receptor tyrosine kinases Tyro3 (zeige TYRO3 Antikörper), Axl (zeige AXL Antikörper), and Mer (zeige ERH Antikörper) and their ligands Gas6 (zeige GAS6 Antikörper) and Protein S.

  5. Data indicate that activated T cells express Pros1.

  6. Results demonstrate that Protein S is a Mer (zeige ERH Antikörper) ligand, and is active in Mer (zeige ERH Antikörper)-driven phagocytosis in the retina.

  7. A self-regulatory mechanism of Toll (zeige TLR4 Antikörper)-like receptor signalling through the suppression of Gas6 (zeige GAS6 Antikörper) and ProS expression is described.

  8. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM (zeige CCNA1 Antikörper) receptor Tyro3 (zeige TYRO3 Antikörper) and sphingosine 1-phosphate receptor1.

  9. results demonstrate that ProS is a pleiotropic anticoagulant with activated Protein C (zeige PROC Antikörper)-independent activities and highlight new roles for ProS in vascular development and homeostasis

  10. Pregnancy causes a decrease in APC (zeige APC Antikörper) resistance in mice, which can be explained by the elevation of protein S levels and increased TFPI (zeige TFPI Antikörper) activity in plasma.

PROS1 Antigen-Profil

Protein Überblick

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.

Genbezeichner und Symbole assoziert mit PROS1

  • protein S (pros1) Antikörper
  • protein S (PROS1) Antikörper
  • protein S (alpha) (Pros1) Antikörper
  • protein S (Pros1) Antikörper
  • AW214361 Antikörper
  • PROS Antikörper
  • PS21 Antikörper
  • PS22 Antikörper
  • PS23 Antikörper
  • PS24 Antikörper
  • PS25 Antikörper
  • PSA Antikörper
  • THPH5 Antikörper
  • THPH6 Antikörper
  • zgc:154001 Antikörper

Bezeichner auf Proteinebene für PROS1

vitamin K-dependent protein S , protein Sa , vitamin K-dependent plasma protein S , vitamin K-dependent protein S preproprotein

768180 Danio rerio
5627 Homo sapiens
397388 Sus scrofa
282006 Bos taurus
100009314 Oryctolagus cuniculus
19128 Mus musculus
81750 Rattus norvegicus
694845 Macaca mulatta
Ausgewählte Anbieter für anti-PROS1 (PROS1) Antikörper
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