anti-Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Antikörper

PROC encodes a vitamin K-dependent plasma glycoprotein. Zusätzlich bieten wir Ihnen PROC Kits (22) und PROC Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PROC 25268 P31394
PROC 19123 P33587
PROC 5624 P04070
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Top anti-PROC Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Pferd Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PROC Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Protein C antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: CEM Cell Lysate Lane 3: SMMC Cell Lysate Lane 4: HELA Cell Lysate Anti-Protein C antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Confocal immunofluorescent analysis of PROC Antibody (Center) (ABIN657466) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western Blot at 1:500-1:1000 dilution Lane 1: human liver lysate Lane 2: human plasma lysate Lysates/proteins at 20 ug per lane. Confocal immunofluorescent analysis of PROC Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Maus Unkonjugiert IP, ELISA, WB PROC monoclonal antibody (M01), clone 3A10. Western Blot analysis of PROC expression in human liver. Immunoprecipitation of PROC transfected lysate using anti-PROC monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with PROC MaxPab rabbit polyclonal antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis on human plasma using anti-vitamin K-dependent protein C polyclonal antibody.        100 μL Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
Details
Human Maus Unkonjugiert WB Western Blot analysis of PROC expression in transfected 293T cell line by PROC MaxPab polyclonal antibody.<br><br>Lane 1: PROC transfected lysate(50.71 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

PROC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Mouse (Murine)


Human ,
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, , , , ,

Am meisten referenzierte anti-PROC Antikörper

  1. Human Polyclonal PROC Primary Antibody für IHC (p), WB - ABIN3044486 : Liu, An, Liu, Li, Tang, Chen: Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses. in Antiviral research 2015 (PubMed)
    Show all 10 Pubmed References

Weitere Antikörper gegen PROC Interaktionspartner

Mouse (Murine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. Data show that activated protein C signals via protease activated receptors PAR2 (zeige F2RL1 Antikörper)/PAR3 (zeige F2RL2 Antikörper) to expand Treg cells, mitigating the disease in mice.

  2. insulin (zeige INS Antikörper) and aPC (zeige APC Antikörper) converge on a common spliced-X-box binding protein-1 (zeige XBP1 Antikörper) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.

  3. loss of the convertase furin (zeige FURIN Antikörper) or PC5 (zeige PCSK5 Antikörper)/6 in hepatocytes results in a approximately 30% decrease in APC (zeige APC Antikörper) levels, with no significant contribution from PACE4 (zeige PCSK6 Antikörper). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (zeige F2 Antikörper) activation.

  4. APC (zeige APC Antikörper) modifies pulmonary fibrosis by limiting thrombin (zeige F2 Antikörper)-dependent macrophage recruitment.

  5. Small interfering RNA-mediated silencing of protein C in apolipoprotein E (zeige APOE Antikörper)-deficient mice creates a condition that allows the occurrence of spontaneous atherothrombosis.

  6. These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (zeige APC Antikörper)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (zeige APC Antikörper) in the context of endotoxemia and infection

  7. activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.

  8. impaired EPCR (zeige PROCR Antikörper)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  9. SOD prevents thrombomodulin (zeige THBD Antikörper) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.

  10. sPLA2 (zeige PLA2G2A Antikörper)-V plays a thrombogenic role by impairing the ability of EPCR (zeige PROCR Antikörper) to promote protein C activation.

Human Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. We recently identified a venous thrombosis patient whose plasma level of protein C antigen is normal, but its anticoagulant activity is only 34 % of the normal level. Genetic analysis revealed that the proband and her younger brother carry a novel heterozygous mutation c.346G>A, p.Gly74Ser (G74S) in PROC.

  2. Developed functional protein S assays that measure both the activated protein C- and TFPI (zeige TFPI Antikörper)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  3. Protein C seems inversely associated with mortality in patients with advanced prostate, lung and pancreatic cancer. Further research should validate protein C as a biomarker for mortality, and explore the effects of protein C on progression of cancer.

  4. Genetically higher protein C was associated with a lower risk of ischaemic heart disease.

  5. EPCR (zeige PROCR Antikörper) occupancy recruits G-protein coupled receptor kinase 5 (zeige GRK5 Antikörper), thereby inducing beta-arrestin-2 (zeige ARRB2 Antikörper) biased PAR1 (zeige MARK2 Antikörper) signaling by both APC (zeige APC Antikörper) and thrombin (zeige F2 Antikörper). In

  6. A novel mutation of A309V in PROC was determined in a family of two patients with late onset protein C deficiency

  7. loss of the convertase furin (zeige FURIN Antikörper) or PC5 (zeige PCSK5 Antikörper)/6 in hepatocytes results in a approximately 30% decrease in APC (zeige APC Antikörper) levels, with no significant contribution from PACE4 (zeige PCSK6 Antikörper). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (zeige F2 Antikörper) activation.

  8. Both probands had hereditary protein C deficiencies, for which their parents were all carriers.

  9. Variants influencing circulating protein C levels in the CELSR2 (zeige CELSR2 Antikörper)-PSRC1 (zeige PSRC1 Antikörper)-SORT1 (zeige SORT1 Antikörper) region may indicate a novel genetic link between lipoprotein metabolism and hemostasis.

  10. These findings suggest that the anti-inflammatory function of APC (zeige APC Antikörper) at therapeutic concentrations may include the inhibition of NETosis in an EPCR (zeige PROCR Antikörper)-, PAR3 (zeige F2RL2 Antikörper)-, and Mac-1 (zeige ITGAM Antikörper)-dependent manner, providing additional mechanistic insight into the diverse functions of neutrophils and APC (zeige APC Antikörper) in disease states including sepsis.

Cow (Bovine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. Activated protein c is a ghrelin (zeige GHRL Antikörper) endopeptidase.

  2. Activated protein C(APC (zeige APC Antikörper)) combined with protein S(PS) had significant antithrombotic effect. APC (zeige APC Antikörper) combined with PS prolonged clotting time. Dependence on APC (zeige APC Antikörper)-cofactor activity of PS for expression of anticoagulant activity by APC (zeige APC Antikörper).

PROC Antigen-Profil

Protein Überblick

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Genbezeichner und Symbole assoziert mit PROC

  • protein C (inactivator of coagulation factors Va and VIIIa), a (proca) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (PROC) Antikörper
  • protein C (inactivator of coagulation factors Va and VIIIa) (PROC) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa S homeolog (proc.S) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (proc) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ000393) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ002754) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003717) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003718) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ014440) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018032) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018737) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (Proc) Antikörper
  • protein C (Proc) Antikörper
  • APC Antikörper
  • MGC64425 Antikörper
  • PC Antikörper
  • PROC Antikörper
  • PROC1 Antikörper
  • si:ch1073-188c16.3 Antikörper
  • THPH3 Antikörper
  • THPH4 Antikörper
  • zgc:63987 Antikörper

Bezeichner auf Proteinebene für PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID SPEZIES
393327 Danio rerio
395085 Gallus gallus
459593 Pan troglodytes
100302329 Ovis aries
380116 Xenopus laevis
548476 Xenopus (Silurana) tropicalis
100231143 Taeniopygia guttata
100448857 Pongo abelii
6031231 Culex quinquefasciatus
6033948 Culex quinquefasciatus
6035053 Culex quinquefasciatus
6035054 Culex quinquefasciatus
6047546 Culex quinquefasciatus
6052150 Culex quinquefasciatus
6052641 Culex quinquefasciatus
25268 Rattus norvegicus
19123 Mus musculus
5624 Homo sapiens
281428 Bos taurus
101096161 Felis catus
476104 Canis lupus familiaris
100051306 Equus caballus
396954 Sus scrofa
100009223 Oryctolagus cuniculus
699077 Macaca mulatta
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