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The protein encoded by PTGFR is member of the G-protein coupled receptor family. Zusätzlich bieten wir Ihnen PTGFR Antikörper (51) und PTGFR Kits (28) und viele weitere Produktgruppen zu diesem Protein an.
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Data suggest that OVGP1 expression in oviductal epithelial cells is enhanced by PGE2 via PTGER2-cAMP-PKA signaling, and reduced by PGF2alpha through PTGFR-Ca2+-PKC pathway. (OVGP1 = oviductal glycoprotein 1; PTGER2 = prostaglandin E2 receptor; PTGFR = prostaglandin F2-alpha receptor; PKA = cyclic AMP-dependent protein kinase; PKC = protein kinase C)
Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (zeige PTGER2 Proteine) (prostaglandin E receptor 2); EP4/PTGER4 (zeige PTGER4 Proteine) (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor).
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (zeige PTGES Proteine)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (zeige TNF Proteine)) and Fas (zeige FAS Proteine) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
COX-2 (zeige PTGS2 Proteine) and FP receptor contribute via changes in amount and distribution to mechanisms associated with parturition.
15-E2t-IsoP acts upon an FP receptor on the cholinergic nerve endings, leading to enhanced neurotransmission.
Data, including data from studies using transgenic mice, suggest that signaling via prostaglandin-F2alpha/Ptgfr and Camk2g (zeige CAMK2G Proteine)/p38 (zeige CRK Proteine)/Foxo1 (zeige FOXO1 Proteine) MAP kinase (zeige MAPK1 Proteine)/calcium pathways are involved in regulation of hepatic gluconeogenesis in both obesity and fasting. (Ptgfr = prostaglandin F2alpha receptor; Camk2g (zeige CAMK2G Proteine) = calcium-calmodulin-dependent protein kinase type 2 gamma; p38 (zeige CRK Proteine) = p38 MAP kinase (zeige MAPK14 Proteine); Foxo1 (zeige FOXO1 Proteine) = forkhead box transcription factor (zeige FOXP2 Proteine) O1)
Silencing of the FP receptor exerts a protective effect on diabetes-induced vascular remodeling
Prostaglandin F-receptor antagonist AS604872 exacerbates vascular inflammation in hypertensive animals, facilitating intracranial aneurysm formation and aortic dissection.
Data suggest that expression of Fabp4 (fatty acid binding protein 4) in preadipocytes is up-regulated by arachidonic acid during adipogenesis; this up-regulation appears mediated by prostaglandin F2alpha/FP (prostaglandin F2alpha receptor) signaling.
it should be clarified as to which EP and/or FP receptor signals are physiologically essential for myometrial contraction and successful parturition.
These data suggest that during cuprizone-induced demyelination, PGF2alpha/FP receptor signaling contributes to glial activation, neuroinflammation, and demyelination, resulting in motor dysfunction
the role of prostaglandin F2alpha receptor (FP) signaling as a regulator of chondrocyte differentiation, was examined.
Low COX-2 activity and the resulting deficiency of PGF2alpha cause increased seizure susceptibility in the immature brain.
The F-prostaglandin receptor is a novel marker for tumor endothelial cells in renal cell carcinoma (zeige MOK Proteine).
Relatively selective localization of prostamide/PGF synthase (zeige C1orf93 Proteine) suggests that myelin sheaths of the CNS may serve as the sites for producing prostamide F(alpha) and/or PGF(alpha), which may contribute to the formation and maintenance of central myelin.
Data, including data from studies using transgenic mice, suggest that signaling via prostaglandin-F2alpha/PTGFR and Camk2g (zeige CAMK2G Proteine)/p38 (zeige CRK Proteine)/Foxo1 (zeige FOXO1 Proteine) MAP kinase (zeige MAPK1 Proteine)/calcium pathways are involved in regulation of hepatic gluconeogenesis in both obesity and fasting. (PTGFR = prostaglandin F2alpha receptor; Camk2g (zeige CAMK2G Proteine) = calcium-calmodulin-dependent protein kinase type 2 gamma; p38 (zeige CRK Proteine) = p38 MAP kinase (zeige MAPK14 Proteine); Foxo1 (zeige FOXO1 Proteine) = forkhead box transcription factor (zeige FOXP2 Proteine) O1)
Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)
The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE).
these results indicated that the actions of AKR1C3 (zeige AKR1C3 Proteine) can produce FP receptor ligands whose activation results in carcinoma cell survival in breast cancer.
The results indicated that the rs12731181 G allele of the Prostaglandin F2alpha Receptor Gene was associated with susceptibility to essential hypertension.
Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients
The SNPs of the PTGFR and MMP-1 (zeige MMP1 Proteine) genes may determine the latanoprost response in a white European Spanish population.
An association was found between SNPs of the FP receptor gene and the response to latanoprost in patients with glaucoma or OH.
The results of this study suggested that significant novel association signals near the genes PTGFR, and provide supportive evidence for the previously reported association signals near ANK3 and within the 3p21.1 locus.
PTGFR gene is not the causative candidate gene for sow maternal behaviors
Down-regulation of PGF2alpha-FP receptor signaling pathway may contribute to myopia onset as retinal PGF2alpha declined in myopic eyes, and antagonism of FP receptor induced a myopic shift in normal vision environment
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
, prostaglandin F2-alpha receptor
, prostaglandin F2alpha receptor
, FP prostanoid receptor
, PGF receptor
, PGF2 alpha receptor
, PGF2-alpha receptor
, prostanoid FP receptor
, prostaglandin F receptor (FP)
, prostaglandin F receptor
, prostaglandin F2-alpha receptor-like
, prostaglandin F2 alpha receptor
, prostaglandin receptor (2-alpha)