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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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KCNA10 in human proximal tubular cells, glomerular and vascular endothelial cells, and also in vascular smooth muscle cells.
Kcna10 is expressed primarily in hair cells of the inner ear and null mutations cause significant vestibular/mild hearing dysfunction.
Kcna10 is most strikingly expressed in the hair cells in late embryonic stage however, at adult stages, however, Kcna10 expression is no longer specific to hair cells.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
Shaker-like voltage-gated potassium channel cKv1.2
, potassium voltage-gated channel subfamily A member 10
, shaker subfamily potassium channel KCNA10
, cyclic GMP gated potassium channel
, voltage-gated potassium channel subunit Kv1.8
, potassium voltage gated channel, shaker related subfamily, member 8
, potassium voltage-gated channel, shaker-related subfamily, member 8