Oxysterol Binding Protein-Like 5 Proteine (OSBPL5)

OSBPL5 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Zusätzlich bieten wir Ihnen Oxysterol Binding Protein-Like 5 Antikörper (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte OSBPL5 OSBPL5 361686  
OSBPL5 114879 Q9H0X9
OSBPL5 79196 Q9ER64
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$9,444.73
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$6,628.57
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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OSBPL5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Oxysterol Binding Protein-Like 5 (OSBPL5) Interaktionspartnern

Cow (Bovine) Oxysterol Binding Protein-Like 5 (OSBPL5) Interaktionspartner

  1. imprinting status of four cattle genes (Tssc4 (zeige TSSC4 Proteine),Nap1l4 (zeige NAP1L4 Proteine), Phlda2 (zeige PHLDA2 Proteine) and Osbpl5) in seven types of tissues, were assessed in cattle.

Human Oxysterol Binding Protein-Like 5 (OSBPL5) Interaktionspartner

  1. ORP5/8 are endoplasmic reticulum (ER) membrane proteins implicated in lipid trafficking that localize to ER-plasma membrane (PM) contacts and maintain membrane homeostasis. Here the authors show that PtdIns(4,5)P 2 plays a critical role in the targeting and function of ORP5/8 at the PM.

  2. mammalian ORP5 and ORP8 (zeige OSBPL8 Proteine) proteins localize to ER-mitochondrial MCS (zeige SMCP Proteine), in addition to ER-PM contact sites.

  3. Results show that OSBPL5 and CALU (zeige CALU Proteine) were expressed at higher levels in the lung tissues of metastasis-positive cases than that in the metastasis-negative cases suggesting they can promote invasiveness of lung cancer cells.

  4. ORP5 and ORP8 (zeige OSBPL8 Proteine) could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 (zeige SACM1L Proteine) for degradation and PS from the ER to the PM.

  5. ORP5 may cooperate with NPC1 (zeige NPC1 Proteine) to mediate the exit of cholesterol from endosomes/lysosomes.

  6. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  7. Telomeric NAP1L4 (zeige NAP1L4 Proteine) and OSBPL5 of the KCNQ1 (zeige KCNQ1 Proteine) cluster, and the DECORIN (zeige DCN Proteine) gene are not imprinted in human trophoblast stem cells.

  8. OSBPL5 is relatd to invasion and poor prognosis in pancreatic cancer.

Mouse (Murine) Oxysterol Binding Protein-Like 5 (OSBPL5) Interaktionspartner

  1. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  2. OSBP (zeige OSBP Proteine) regulates hepatic TG metabolism and suggest the involvement of OSBP (zeige OSBP Proteine) in the insulin (zeige INS Proteine) signaling pathways that control hepatic lipogenesis.

Oxysterol Binding Protein-Like 5 (OSBPL5) Protein Überblick

Protein Überblick

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit OSBPL5

  • oxysterol binding protein-like 5 (Osbpl5)
  • oxysterol binding protein like 5 (OSBPL5)
  • oxysterol binding protein like 5 (osbpl5)
  • 1110006M06Rik Protein
  • AI462538 Protein
  • MGC109308 Protein
  • Obph1 Protein
  • ORP5 Protein
  • Osbp2 Protein
  • OSBPL5 Protein

Bezeichner auf Proteinebene für OSBPL5

oxysterol binding protein-like 5 , oxysterol-binding protein-related protein 5-like , ORP-5 , OSBP-related protein 5 , oxysterol-binding protein homolog 1 , oxysterol-binding protein homologue 1 , oxysterol-binding protein-related protein 5 , oxysterol binding protein 2 , oxysterol binding protein homolog 1 , oxysterol-binding protein-like protein 5

GENE ID SPEZIES
361686 Rattus norvegicus
483671 Canis lupus familiaris
532690 Bos taurus
770816 Gallus gallus
100431919 Pongo abelii
100466215 Ailuropoda melanoleuca
100515995 Sus scrofa
100539452 Meleagris gallopavo
100564429 Anolis carolinensis
114879 Homo sapiens
79196 Mus musculus
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