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Alternatively spliced transcript variants have been found for OTUD4.
Showing 3 out of 3 products:
There is an evolutionary loss of activity in de-ubiquitylating enzymes of the OTU family, OTUD4, otu, and CG3251.
OTUD4 is a positive regulator of ALKBH2 (zeige ALKBH2 Proteine) and ALKBH3 (zeige ALKBH3 Proteine), two DNA demethylases critical for alkylation repair.
The syndrome of hypogonadotropic hypogonadism, ataxia, and dementia can be caused by inactivating mutations in RNF216 or by the combination of mutations in RNF216 and OTUD4
Alternatively spliced transcript variants have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells.
OTU domain containing 4
, OTU domain-containing protein 4-like
, HIV-1 induced protein HIN-1
, HIV-1-induced protein HIN-1
, OTU domain-containing protein 4