ORAI Calcium Release-Activated Calcium Modulator 2 Proteine (ORAI2)

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity). Zusätzlich bieten wir Ihnen ORAI2 Antikörper (37) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ORAI2 ORAI2 304592  
ORAI2 100043803  
ORAI2 80228 Q96SN7
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details

ORAI2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) Interaktionspartnern

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) Interaktionspartner

  1. results identified the ORAI-NOX2 (zeige CYBB Proteine) feedback loop as a determinant of monocyte immune responses.

  2. The data from this study indicate that upregulation of STIM2 (zeige Stim2 Proteine) and Orai2 is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  3. Data indicate that the Ca(2 (zeige CA2 Proteine)+) release-activated Ca(2 (zeige CA2 Proteine)+) channels (CRAC) blocker GSK-7975A inhibited store-operated Ca(2 (zeige CA2 Proteine)+) entry in a concentration-dependent manner.

Human ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) Interaktionspartner

  1. results identified the ORAI-NOX2 (zeige CYBB Proteine) feedback loop as a determinant of monocyte immune responses.

  2. Orai1, Orai2 and STIM1 (zeige STIM1 Proteine) form functional Ca(2 (zeige CA2 Proteine)+) release-activated Ca(2 (zeige CA2 Proteine)+) channels in OUMS-27 cells (chondrocytes) and that these complexes are responsible for sustained Ca(2 (zeige CA2 Proteine)+) entry in response to agonist stimulation.

  3. The higher amplitude of store-operated Ca2 (zeige CA2 Proteine)+ entry was associated to the over-expression for Stim2 (zeige Stim2 Proteine), Orai2-3, and TRPC1 (zeige TRPC1 Proteine) while Stim2 (zeige Stim2 Proteine) levels remained constant and Stim1 (zeige STIM1 Proteine), Orai1, Orai3, TRPC1 (zeige TRPC1 Proteine) and TRPC4 (zeige TRPC4 Proteine) proteins were over-expressed in primary myelofibrosis.

  4. Orai1 but not Orai2 plays a major role in the influx of extracellular Ca2 (zeige CA2 Proteine)+ into and mediator release from HLMCs following their activation

  5. Orai1 and Orai2 operate in a STIM-dependent manner, Orai3 does not interact with STIM isoforms upon calcium store depletion in platelets.

  6. With these data we show a new Ca(2 (zeige CA2 Proteine))(+) entry pathway linked to the Ca(2 (zeige CA2 Proteine))(+)/inositolphosphate second-messenger system in RPE (zeige RPE Proteine) cells which help to further understand regulatory pathways of agonists.

  7. Results suggest that Orai1, -2, and -3 channels are similarly inhibited by extracellular calcium, indicating similar affinities for Ca(2 (zeige CA2 Proteine)+) within the selectivity filter.

  8. The effects of 2-aminoethoxydiphenyl borate on orai1, orai2, orai3 metabolism in HEK293 cells with and without STIM1 (zeige STIM1 Proteine) are reported.

  9. analysis of activation of Orai1-3 channels by a STIM1 (zeige STIM1 Proteine) coiled-coil mutant

  10. Data show that the fast Ca(2+)-dependent inactivation is mediated by three conserved glutamates in the C termini (CT) of Orai2 and Orai3, which show prominent fast Ca(2+)-dependent inactivation compared with Orai1.

Cow (Bovine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) Interaktionspartner

  1. Orai2 is specifically up-regulated during the G2/M phase, negatively modulates the store-operated Ca(2 (zeige CA2 Proteine)+) entry activity, and may contribute to the regulation of cell cycle progression in brain capillary endothelial cells.

ORAI2 Protein Überblick

Protein Überblick

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity).

Genbezeichner und Symbole assoziert mit ORAI2

  • ORAI calcium release-activated calcium modulator 2 (Orai2)
  • ORAI calcium release-activated calcium modulator 2 (ORAI2)
  • predicted gene 4659 (Gm4659)
  • ORAI calcium release-activated calcium modulator 2 (LOC100230993)
  • ORAI calcium release-activated calcium modulator 2 (LOC100349347)
  • ORAI calcium release-activated calcium modulator 2 (LOC100358487)
  • ORAI calcium release-activated calcium modulator 2 (LOC100359269)
  • ORAI calcium release-activated calcium modulator 2 (orai2)
  • A730041O15Rik Protein
  • C7orf19 Protein
  • CBCIP2 Protein
  • LOC100230993 Protein
  • MEM142B Protein
  • Orai2 Protein
  • RGD1310213 Protein
  • Tmem142b Protein

Bezeichner auf Proteinebene für ORAI2

CAP-binding protein complex interacting protein 2 , calcium release-activated calcium modulator 2 protein , ORAI calcium release-activated calcium modulator 2 , calcium release-activated calcium channel 2 , CAP-binding protein complex-interacting protein 2 , H_NH0514P08.8 , protein orai-2 , putative protein ORAI2-2 , transmembrane protein 142B

GENE ID SPEZIES
304592 Rattus norvegicus
463930 Pan troglodytes
100043803 Mus musculus
100230993 Taeniopygia guttata
100349347 Oryctolagus cuniculus
100358487 Oryctolagus cuniculus
100359269 Oryctolagus cuniculus
100380109 Xenopus (Silurana) tropicalis
80228 Homo sapiens
269717 Mus musculus
608106 Canis lupus familiaris
511233 Bos taurus
417509 Gallus gallus
Ausgewählte Anbieter für ORAI2 Proteine (ORAI2)
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