anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Antikörper

NSMAF encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human NSMAF NSMAF 8439 Q92636
Anti-Maus NSMAF NSMAF 18201 O35242
Anti-Ratte NSMAF NSMAF 353233  
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Top anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Antikörper auf antikoerper-online.de

Showing 10 out of 52 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Western Blot analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human T(gastric cancer) , using NSMAF, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Maus Kaninchen Unkonjugiert IHC (p), WB NSMAF Antibody (N-term) (ABIN657508) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane). This demonstrates the NSMAF antibody detected the NSMAF protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-31431] - Paraffin-embedded T(gastric CA), using antibody at 1:100 dilution. Western Blot: NSMAF Antibody [NBP1-31431] - Analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE, antibody diluted at 1:500. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: NSMAF Antibody [NBP1-84737] - Staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells. Immunohistochemistry-Paraffin: NSMAF Antibody  - Staining of human tonsil shows moderate cytoplasmic positivity in both germinal and non-germinal center cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry: NSMAF Antibody [NBP1-84736] - Staining of human colon shows moderate cytoplasmic positivity in glandular cells. Western Blot: NSMAF Antibody [NBP1-84736] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418576) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: NSMAF Antibody [NBP1-84735] - Staining of human cell line A-431 shows positivity in nucleoli. Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-84735] - Staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse intestines, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. Paraformaldehyde-fixed, paraffin embedded Mouse stomach, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$306.90
Details
Maus Kaninchen Unkonjugiert IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details

Weitere Antikörper gegen Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Interaktionspartner

Human Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Interaktionspartner

  1. The interaction of FAN with receptor for activated C-kinase 1 (RACK1 (zeige GNB2L1 Antikörper)) appears to be dependent on the folding of the WD repeats into a secondary structure, because no linear binding motifs are identified in the WD-repeat region of FAN.

  2. sphingolipid activator proteins like domain may stabilize the fold of acid sphingomyelinase (zeige SMPD1 Antikörper)

  3. Regulation of NSMAF by TNF-alpha (zeige TNF Antikörper) involves PRKCD (zeige PKCd Antikörper) in lung epithelial cells.

Mouse (Murine) Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Interaktionspartner

  1. FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of tumor necrosis factor (zeige TNF Antikörper).

  2. FAN is not implicated in the development of methionine and choline deficient diet-induced non-alcoholic steatohepatitis.

  3. the role of FAN and IL-6 (zeige IL6 Antikörper) in the inflammatory response initiated by endotoxin, implicating TNFalpha (zeige TNF Antikörper)

  4. FAN mediates activation of N-SMase as well as regulation of lysosome size by signaling pathways that operate independent from activation/membrane recruitment of PKC.

  5. The results of this study suggest that PH-mediated plasma membrane targeting of FAN is critically involved in tumor necrosis factor (zeige TNF Antikörper)-induced Cdc42 (zeige CDC42 Antikörper) activation and cytoskeleton reorganization.

  6. This is the first report to demonstrate that TNFalpha (zeige TNF Antikörper)-induced sickness behavior is fully mediated by TNF-R1 (zeige TNFRSF1A Antikörper) and that the adaptor protein FAN is a necessary intracellular intermediate for sickness behavior

  7. these results indicate the involvement of FAN in TNF (zeige TNF Antikörper)-induced gene expression and leukocyte recruitment, contributing to the establishment of the specific immune response.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Antigen-Profil

Protein Überblick

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit NSMAF

  • protein FAN (EDI_035100) Antikörper
  • neutral sphingomyelinase activation associated factor (NSMAF) Antikörper
  • neutral sphingomyelinase (N-SMase) activation associated factor (Nsmaf) Antikörper
  • neutral sphingomyelinase activation associated factor (Nsmaf) Antikörper
  • AA959567 Antikörper
  • C630007J05 Antikörper
  • Fan Antikörper

Bezeichner auf Proteinebene für NSMAF

protein FAN , factor associated with N-SMase activation , factor associated with neutral sphingomyelinase activation

GENE ID SPEZIES
5884688 Entamoeba dispar SAW760
8439 Homo sapiens
18201 Mus musculus
353233 Rattus norvegicus
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