anti-Neuronal Calcium Sensor 1 (NCS1) Antikörper

NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. Zusätzlich bieten wir Ihnen NCS1 Proteine (14) und NCS1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NCS1 65153 P62168
NCS1 23413 P62166
NCS1 14299 Q8BNY6
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Top anti-NCS1 Antikörper auf antikoerper-online.de

Showing 10 out of 81 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Immunohistochemistry with Small intestine, myetneric plexus tissue at an antibody concentration of 5-10µg/ml using anti-FREQ antibody (ARP34711_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-FREQ Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB FREQ Antibody (N-term) (ABIN658493) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FREQ antibody detected the FREQ protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of NCS-1 with rat kidney tissue lysate. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of NCS1 Antibody (Center) (ABIN388386) in MCF-7 cell line lysates (35 µg/lane). NCS1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with NCS1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, WB Western blot analysis of NCS-1 on a rat cerebrum lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the anti- NCS-1 antibody. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:A431, B:Hep G2, 12% SDS PAGE antibody diluted at 1:200 IHC-P Image NCS1 antibody detects NCS1 protein at on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. NCS1 antibody , dilution: 1:500. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of NCS1 Antibody in MCF-7 cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human breast carcinoma reacted with NCS1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Maus Kaninchen Unkonjugiert WB Hippocampal neurons were prepared from 17 d old NMRI mice and grown as described previously (G. Grosse et al., (2000) J. Neurosci. 20: 1869-1882).  The figure shows the distribution of neuronal calcium sensor-1 (NCS-1) (red) and synaptobrevin (green) in hippo-campal cell cultures after 19 d in vitro.  Numer-ous synapses immunoreactive for synaptobrevin also show NCS-1 immunoreactivity.   NCS-1 derived from invertebrate homologs has been referred to as frequenin. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details

NCS1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-NCS1 Antikörper

  1. Human Monoclonal NCS1 Primary Antibody für IF, WB - ABIN968601 : Braunewell, Gundelfinger: Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function. in Cell and tissue research 1999 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal NCS1 Primary Antibody für IHC, WB - ABIN2775968 : Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008 (PubMed)

  3. Cow (Bovine) Polyclonal NCS1 Primary Antibody für IHC, WB - ABIN2775722 : OCallaghan, Burgoyne: Identification of residues that determine the absence of a Ca(2+)/myristoyl switch in neuronal calcium sensor-1. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen NCS1 Interaktionspartner

Human Neuronal Calcium Sensor 1 (NCS1) Interaktionspartner

  1. NCS-1, a calcium-binding protein (zeige CETN1 Antikörper), is associated with clinicopathologic features of aggressiveness in breast cancer cells and worse outcome in two breast cancer patient cohorts

  2. Results show that although NCS-1 Var2mRNA can be detected, protein expression was not detectable. When overexpressed in cell lines NCS-1 Var2 appears to be folded properly, yet it has a lower calcium affinity. Because most NCS-1 binding to its protein partners requires calcium binding, it is unlikely that NCS-1 Var2 would play a major regulatory role in cells.

  3. structural and dynamical response of NCS-1 protein to elevated temperature may be one of its intrinsic functional properties

  4. Lithium normalizes gamma band oscillations mediated by P/Q-type calcium channels modulated by NCS-1.

  5. Study determined the salient features of the folding free-energy landscapes of the Mg2 (zeige MUC7 Antikörper)+-bound and apo (zeige C9orf3 Antikörper) states of NCS-1

  6. results reveal the important role of salt bridges on the structural properties of NCS-1 protein and that R102Q mutation disables the dynamic relocation of C-terminus, which may block the binding of NCS-1 protein to its receptors

  7. single-molecule optical tweezers were used to monitor misfolding reactions of the human neuronal calcium sensor-1.

  8. A strong liason was characterized between myristoylation and cryptic EF-1 (zeige EEF1D Antikörper) in NCS-1.

  9. The functional link in substantia nigra dopamine neurons between Cav1.3 (zeige CACNA1D Antikörper)- L-type-Ca2 (zeige CA2 Antikörper)+ channels and D2-autoreceptor activity is an adaptive signalling network controlled by NCS-1.

  10. NCS1 has evolved a remarkable complex interdomain cooperativity and a fundamentally different folding mechanism compared to structurally related proteins.

Mouse (Murine) Neuronal Calcium Sensor 1 (NCS1) Interaktionspartner

  1. Phosphorylation of CaMKII-alpha, known to trigger long-term potentiation and increase BDNF levels, was significantly reduced in the Ncs1-/- mouse brain. Further, electric potential stimulation, which increases the levels of BDNF and promotes spatial learning, significantly increased the levels of NCS-1 concomitant with phosphorylated CaMKII-alpha in the hippocampus; suggesting a close relationship between NCS-1 and CaM...

  2. these data demonstrate that NCS-1 contributes to stress tolerance in cardiomyocytes at least in part by activating certain Ca(2 (zeige CA2 Antikörper)+)-dependent survival pathways that promote mitochondrial biosynthesis/function and detoxification pathways.

  3. These studies identify novel roles for NCS-1 in regulating activity-dependent striatal dopamine release and aspects of motivated behavior

  4. elevated expression of neuronal calcium sensor 1 (Ncs1) and dopamine type-2 receptors upon self-directed exploration, is reported.

  5. IGF-1 (zeige IGF1 Antikörper) strengthens the interaction between NCS-1 and IP3R (zeige ITPR1 Antikörper) in the process of regulation of nuclear Ca2 (zeige CA2 Antikörper)+ signaling in cardiomyocytes.

  6. data implicate NCS-1 in exploratory activity, memory and mood-related behaviors, suggesting that NCS-1 gene ablation may result in phenotypic abnormalities associated with neuropsychiatric disorders

  7. NCS-1 transgene is upregulated in hypertrophic hearts, while hormone-induced hypertrophy is largely prevented in Ncs1-deficient hearts.

  8. NCS-1 is an accessory subunit of Kv4 (zeige KCNC1 Antikörper)-encoded I(to,f) channels that functions to regulate I(to,f) density in the mammalian myocardium.

  9. PI 4-kinase functions to negatively regulate GLUT4 (zeige SLC2A4 Antikörper) translocation through its interaction with NCS-1.

  10. NCS-1 should be considered an important potential Kv4 (zeige KCNC1 Antikörper) regulatory subunit, particularly in the immature heart.

Cow (Bovine) Neuronal Calcium Sensor 1 (NCS1) Interaktionspartner

  1. C-terminal segment of NCS1 regulates reuptake of myristoyl group under Ca(2 (zeige CA2 Antikörper)+)-free conditions and participates in organization of the target-binding pocket of the protein. We show putative role of NCS1 in photoreceptors as a modulator of GRK (zeige GRK4 Antikörper) activity

  2. NCS-1-ARF1 (zeige ARF1 Antikörper) interaction provides evidence for functional cross-talk between Ca(2 (zeige CA2 Antikörper)+)-dependent and ARF-dependent pathways in TGN (zeige TG Antikörper) to plasma membrane traffic

  3. Frequenin (BovFrq) native to the bovine hippocampus has been purified, sequenced for its 9 internal fragments, cloned, and studied.

Zebrafish Neuronal Calcium Sensor 1 (NCS1) Interaktionspartner

  1. findings reveal a novel signalling pathway involved in development of the semicircular canal system, and suggest a previously unrecognized role for NCS-1 in mitochondrial function via its association with several mitochondrial proteins.

NCS1 Antigen-Profil

Protein Überblick

This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit NCS1

  • neuronal calcium sensor 1 (NCS1) Antikörper
  • frequenin homolog (freq) Antikörper
  • neuronal calcium sensor 1 (ncs1) Antikörper
  • calcium sensor-1 (cse-1) Antikörper
  • neuronal calcium sensor 1 (MGYG_03475) Antikörper
  • calcium-binding protein NCS-1 (PGTG_09250) Antikörper
  • neuronal calcium sensor 1 (Tsp_06748) Antikörper
  • Neuronal calcium sensor 1 (ncs1) Antikörper
  • neuronal calcium sensor 1 (Ncs1) Antikörper
  • neuronal calcium sensor 1 L homeolog (ncs1.L) Antikörper
  • neuronal calcium sensor 1a (ncs1a) Antikörper
  • Neuronal calcium sensor 1 (ncs-1) Antikörper
  • 9430075O15Rik Antikörper
  • A730032G13Rik Antikörper
  • AI836659 Antikörper
  • FLUP Antikörper
  • Freq Antikörper
  • freqa Antikörper
  • LOC100189965 Antikörper
  • Mfreq Antikörper
  • MGC75953 Antikörper
  • NCS-1 Antikörper
  • xfreq Antikörper
  • zgc:63620 Antikörper

Bezeichner auf Proteinebene für NCS1

putative frequenin , frequenin homolog , frequenin-like protein , neuronal calcium sensor 1 , NCS-1 , Neuronal calcium sensor 1 , frequenin-like ubiquitous protein , neuronal calcium sensor-1 , frequenin , neuronal calcium sensor homologue , frequenin homolog a , ncs-1a , neuronal calcium sensor-1a

GENE ID SPEZIES
100189965 Taeniopygia guttata
100303592 Saccoglossus kowalevskii
100340886 Oryctolagus cuniculus
394570 Xenopus (Silurana) tropicalis
3873635 Neurospora crassa OR74A
10028582 Arthroderma gypseum CBS 118893
10545012 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10911856 Trichinella spiralis
100172236 Pongo abelii
100380555 Salmo salar
65153 Rattus norvegicus
23413 Homo sapiens
14299 Mus musculus
399297 Xenopus laevis
396336 Gallus gallus
526544 Bos taurus
393437 Danio rerio
180448 Caenorhabditis elegans
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