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NGB encodes an oxygen-binding protein that is distantly related to members of the globin gene family. Zusätzlich bieten wir Ihnen Neuroglobin Antikörper (85) und Neuroglobin Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 58 products:
Rat (Rattus) Neuroglobin ELISA Kit für Sandwich ELISA - ABIN368272
Di Pietro, Lazzarino, Amorini, Tavazzi, DUrso, Longo, Vagnozzi, Signoretti, Clementi, Giardina, Lazzarino, Belli: Neuroglobin expression and oxidant/antioxidant balance after graded traumatic brain injury in the rat. in Free radical biology & medicine 2014
Rat (Rattus) Neuroglobin ELISA Kit für Sandwich ELISA - ABIN416091
Zhang, Ai, Gong, Guo, Huang, Liu, Yao: Expression and role of neuroglobin in rats with sepsis-associated encephalopathy. in Critical care medicine 2013
Results show that the expression of NGB (zeige GTPBP4 ELISA Kits) in glioma is grade related and is negatively regulated at the transcriptional level by PPARgamma (zeige PPARG ELISA Kits) suggesting an important role of NGB (zeige GTPBP4 ELISA Kits) in glioma progression.
The authors demonstrate that Glu53, Glu60, and Glu118 of human Ngb (zeige GTPBP4 ELISA Kits) are crucial for both the neuroprotective activity and interaction with Gi. Moreover, they show that Lys46, Lys70, Arg208, Lys209, and Lys210 residues of Gi are important for binding to human Ngb (zeige GTPBP4 ELISA Kits).
Ngb-H64Q-CCC binds CO about 500 times more strongly than hemoglobin, which could be useful in detecting and eliminating carbon monoxide poisoning
these results highlight the involvement of ERa activation and of E2/ERa-dependent NGB (zeige GTPBP4 ELISA Kits) upregulation in the insensitivity of MCF-7 to paclitaxel. These novel findings could have important implications in the development of targeted therapeutics for overcoming paclitaxel insensitivity in ERa-positive human breast cancer
Knockdown of GATA-2 (zeige GATA2 ELISA Kits) caused NGB (zeige GTPBP4 ELISA Kits) expression to drop dramatically, indicating GATA-2 (zeige GATA2 ELISA Kits) as an essential transcription factor for the activation of NGB (zeige GTPBP4 ELISA Kits) expression via binding to a novel distal regulatory element of NGB (zeige GTPBP4 ELISA Kits).
analysis of how the interaction of hydrogen sulfide with human neuroglobin is muted by a distal ligand
NO oxidation kinetics at physiological NO concentrations. The use of a polarized electrode to efficiently interconvert the ferric (Fe(3+)) and ferrous (Fe(2+)) forms of an immobilized NGB (zeige GTPBP4 ELISA Kits) showed that the disulfide bridge both defines the kinetics of NO dioxygenase activity and regulates appearance of the free ferrous deoxy-NGB (zeige GTPBP4 ELISA Kits), which is the redox active form of the protein in contrast to oxy (zeige GCG ELISA Kits)-NGB (zeige GTPBP4 ELISA Kits).
Taken together, this work support the first evidence that Ngb (zeige GTPBP4 ELISA Kits) can be potentially used as a promising biomarker and target for novel treatment of human glioma
The (zeige GTPBP4 ELISA Kits) cochlear nuclei and superior olivary complex (SOC) also express considerable amounts of Ngb. Within the human SOC, many medial superior olive neurons, and scattered neurons in the LSO, were Ngb-immunoreactive
Study characterized the presence of Ngb (zeige GTPBP4 ELISA Kits) in the human cochlea
Ngb can bind to mitochondrial complex III subunit Cyc1 (zeige CYC1 ELISA Kits), leading to suppression of oxygen-glucose deprivation -mediated complex III activity.
Reduction of Ngb expression in mouse retina after optic nerve injury.Ngb role in neuroregeneration in mice after optic nerve injury.
Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF (zeige REST ELISA Kits) being an upstream regulator.
Ngb expression is limited to the subpopulation of type I spiral ganglion cells, those which innervate inner hair cells, while the subpopulation of type II spiral ganglion cells which innervate the outer hair cells do not express Ngb. The cochlear nuclei and superior olivary complex (SOC) also express considerable amounts of Ngb.
Ngb functions as a metabolic regulator and enhances cellular anabolism through the inhibition of AMPK (zeige PRKAA1 ELISA Kits) signaling.
Data show that the neuroglobin (Ngb) protein was downregulated in the retinal ganglion cells after optic nerve injury.
Overexpression of neuroglobin reduced sensorimotor deficits following TBI. An endogenous increase in neuroglobin expression occurs during the subacute period. Increasing neuroglobin expression during the acute period after TBI may improve recovery.
reflect lesser perturbations produced by acute inhalation of combustion smoke in the Ngb overexpressing mouse, suggesting that Ngb mitigates mitochondrial dysfunction and neurotoxicity and raises the threshold of smoke inhalation-induced brain injury
A critical role for neuroglobin is demonstrated via its differential interaction with phosphatase and tensin homolog (PTEN) and Akt during neurite induction.
Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest.
The zebrafish Neuroglobin can catalyze the reduction of nitrite to nitric oxide with a broad range of reaction rate constants.
Data show that the neuroglobin (Ngb) protein was upregulated in the amacrine cells after optic nerve injury.
Chimeric Myoglobin (zeige MB ELISA Kits) has a cell-membrane-penetrating activity similar to zebrafish Ngb.
Neuroglobin appears to be associated with mitochondria-rich cell types and thus oxygen consumption rates, suggesting a myoglobin (zeige MB ELISA Kits)-like function of this protein in facilitated oxygen diffusion
both zebrafish and chimeric ZHHH Ngb can penetrate cell membranes in the absence of Chariot
Ngb overexpression may have potential therapeutic benefits for both reducing secondary damages and improving the outcomes after traumatic spinal cord injury
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.