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NBEA encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Zusätzlich bieten wir Ihnen Neurobeachin Antikörper (40) und und viele weitere Produktgruppen zu diesem Protein an.
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This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.
lysosomal trafficking regulator 2
, lysosomal-trafficking regulator 2
, A kinase anchor protein 550
, drosophila A kinase anchor protein
, LOW QUALITY PROTEIN: neurobeachin