Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) ELISA Kits

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Zusätzlich bieten wir Ihnen Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 Antikörper (87) und Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.

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NCR3LG1 374383 Q68D85
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.12 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
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Weitere ELISA Kits für Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 Interaktionspartner

Human Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) Interaktionspartner

  1. B7-H6 was expressed in gliomas and correlated with glioma progression. Knockdown of B7-H6 inhibited glioma cell proliferation, colony formation, migration, and invasion via upregulation of E-cadherin and Bax, and downregulation of vimentin, N-cadherin, MMP-2, MMP-9 and survivin.

  2. these studies find that soluble B7H6 is constitutively expressed during pregnancy

  3. Data suggest that B7-H6 play an important role in the regulation of the biological behavior of glioma cells.

  4. Data indicate a sequence of events driven by tumour-derived prostaglandin D2 (PGD2) associated with engagement of the natural cytotoxicity triggering receptor 3 (NKp30)-B7H6 antigen (B7H6) pathway leading to significant group 2 innate lymphoid cells (ILC2s) activation and expansion.

  5. B7H6-derived peptides trigger TNF-alpha-dependent immunostimulatory activity of lymphocytic NK92-MI cells.

  6. Study confirms that B7-H6 is widely expressed in B-cell lymphomas and demonstrates its important role in the pathogenesis and chemosensitivity of lymphoma.

  7. our present data revealed that higher B7-H6 expression in ovarian cancer tissues was positively correlated with tumor metastasis and cancer progression

  8. NKp30-B7-H6 interaction is a novel cell contact mechanism that mediates activation of Group 2 innate lymphoid cells and identifies a potential target for the development of novel therapeutics for atopic dermatitis and other atopic diseases.

  9. study not only reveals the possibility that tumor therapeutics work as stress inducers to enhance tumor sensitivity to NK cell cytolysis but also suggests that B7-H6 could be a potential target for tumor therapy in the future

  10. Our results suggest that NKP30-B7-H6 interaction can aggravate hepatocyte damage, probably through up-regulation of IL-32 expression in hepatitis B virus-related acute-on-chronic liver failure

  11. the interaction between NKp30 and B7-H6 may contribute to the fate of neuroblastoma patients

  12. Study suggests that B7-H6 has a limited value as a prognostic marker in non-small cell lung cancer patients.

  13. this study identified ectodomain shedding of B7-H6 by the metalloproteases "a disintegrin and metalloproteases" (ADAM)-10 and ADAM-17 from the cell surface of tumor cells as a crucial mechanism of expression regulation of B7-H6.

  14. B7-H6-positive carcinomas were significantly associated with a higher differentiation.

  15. Allogeneic and xenogeneic anti-tumor effect of callithrix jacchus natural killer cells is dependent on NKp30 and B7-H6 interaction.

  16. Data indicate that the ectodomain of NKp30 forms functional homo-oligomers that mediate high affinity binding to its corresponding cellular ligand B7-H6.

  17. These findings reveal that B7-H6 is not only implicated in tumor immunosurveillance but also participates in the inflammatory response in infectious conditions.

  18. B7-H6:7D8 represents the first Ab-based molecule stimulating NKp30-mediated NK cell cytotoxicity for therapeutic purposes

  19. The NKp30-B7-H6 structure revealed that this NK cell activating complex is distinct from the CTLA4-B7 and PD-1-PD-L T cell inhibitory complexes in both overall organization and detailed atomic interactions that mediate binding and specificity.

  20. DKFZp686O24166 was designated the gene B7-H6; identification as a tumor cell surface molecule that binds NKp30, a receptor which triggers antitumor NK cell cytotoxicity and cytokine secretion

Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) Antigen-Profil

Beschreibung des Gens

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3\; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009

Genbezeichner und Symbole assoziert mit NCR3LG1

  • natural killer cell cytotoxicity receptor 3 ligand 1 (NCR3LG1) Antikörper
  • B7-H6 Antikörper
  • B7H6 Antikörper
  • DKFZp686O24166 Antikörper

Bezeichner auf Proteinebene für NCR3LG1

B7 homolog 6 , natural cytotoxicity triggering receptor 3 ligand 1 , putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167

GENE ID SPEZIES
374383 Homo sapiens
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