anti-NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Antikörper

The protein encoded by NEK6 is a kinase required for progression through the metaphase portion of mitosis. Zusätzlich bieten wir Ihnen NEK6 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NEK6 59126 Q9ES70
NEK6 10783 Q9HC98
NEK6 360161 P59895
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Top anti-NEK6 Antikörper auf antikoerper-online.de

Showing 10 out of 73 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: NEK6 Antibody [NLS7305] - Analysis of anti-NEK6 antibody with human brain, Purkinje neurons at 13 ug/ml. Immunohistochemistry-Paraffin: NEK6 Antibody  - Anti-NEK6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
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Human Maus Unkonjugiert IHC (p), IP, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-NEK6 antibody  ABIN1049089 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-NEK6 antibody  ABIN1049089 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of Nek6 (arrow) using rabbit polyclonal Mouse Nek6 Antibody (C-term) (ABIN657847). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Nek6 gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of NEK6 (arrow) using rabbit polyclonal NEK6 Antibody (N-term) (ABIN1882104) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NEK6 gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert FACS, IF, IP, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-NEK6 mouse monoclonal antibody. (ABIN2452655, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-NEK6mouse monoclonal antibody. (ABIN2452655, Dilution 1:50) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details

NEK6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-NEK6 Antikörper

  1. Human Polyclonal NEK6 Primary Antibody für WB - ABIN1882104 : Belham, Roig, Caldwell, Aoyama, Kemp, Comb, Avruch: A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen NEK6 Interaktionspartner

Mouse (Murine) NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. NEK6 is overexpressed in various human cancer tissues, and ectopic expression of NEK6 increases tumor promoter-induced transformation of JB6 Cl41 mouse epidermal cells.

  2. During early embryogenesis nek6 is highly expressed in primary giant trophoblast cells. Later in embryogenesis, nek6 is found in ventricular and sub-ventricular regions.

Arabidopsis thaliana NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. NEK6 (zeige NEK5 Antikörper) forms heterodimers with NEK4 and NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of beta-tubulins.

Human NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. cis (zeige CISH Antikörper)-regulatory circuits that lead to overexpression of NEK6, a mitosis-associated kinase, in human B cell lymphoma, were analyzed.

  2. High NEK6 expression is associated with Cluster Amplified Centrosomes in cancer.

  3. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7 (zeige NEK7 Antikörper), and Nek9 (zeige NEK9 Antikörper) is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 (zeige KIF20A Antikörper) and Kif14 (zeige KIF14 Antikörper) to properly coordinate cytokinesis.

  4. our studies establish NEK6 signaling as a central mechanism mediating castration-resistant prostate cancer

  5. overexpression of PAK1 (zeige PAK1 Antikörper), NEK6, AURKA (zeige AURKA Antikörper), and AURKB (zeige AURKB Antikörper) genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

  6. We found that NEK6-mediated phosphorylation of TPP1 (zeige TPP1 Antikörper) Ser255 in G2/M phase regulates the association between telomerase activity and TPP1 (zeige TPP1 Antikörper). Furthermore, we found evidence that POT1 (zeige POT1 Antikörper) negatively regulates TPP1 (zeige TPP1 Antikörper) phosphorylation because the level of Ser255 phosphorylation was elevated when telomeres were elongated by a POT1 (zeige POT1 Antikörper) mutant lacking its OB-fold domains

  7. Overexpression of AURKA (zeige AURKA Antikörper) and NEK6 genes was significantly more pronounced in Ulcerative colitis patients with more extensive colon involvement

  8. NEK6 suppresses the cell growth arrest induced by TGFbeta (zeige TGFB1 Antikörper). Mechanically, NEK6 blocks nuclear translocation of Smad4 (zeige SMAD4 Antikörper), which is essential for TGFbeta (zeige TGFB1 Antikörper) function.

  9. Nek6 is also a critical signaling molecule that helps prevent cardiac hypertrophy and inhibits the Akt (zeige AKT1 Antikörper) signaling pathway.

  10. Nek6 facilitates association of Hsp72 (zeige HSPA1A Antikörper) with the mitotic spindle, where it promotes stable K-fiber assembly through recruitment of the ch-TOG (zeige CKAP5 Antikörper)-TACC3 (zeige TACC3 Antikörper) complex.

NEK6 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit NEK6

  • NIMA (never in mitosis gene a)-related expressed kinase 6 (Nek6) Antikörper
  • NIMA-related kinase 6 (nek6) Antikörper
  • NIMA related kinase 6 (NEK6) Antikörper
  • Serine/Threonine kinase catalytic domain protein (NEK5) Antikörper
  • NIMA-related kinase 6 S homeolog (nek6.S) Antikörper
  • NIMA-related kinase 6 (Nek6) Antikörper
  • 1300007C09Rik Antikörper
  • ATNEK5 Antikörper
  • MOE17.17 Antikörper
  • NIMA-related kinase 5 Antikörper
  • NIMA-RELATED KINASE5 Antikörper
  • si:ch211-167p9.4 Antikörper
  • SID6-1512 Antikörper

Bezeichner auf Proteinebene für NEK6

NIMA-related expressed kinase 6 , never in mitosis A-related kinase 6 , nimA-related protein kinase 6 , serine/threonine-protein kinase Nek6 , putative serine-threonine protein kinase , NIMA (never in mitosis gene a)-related kinase 6 , protein kinase SID6-1512 , NIMA (never in mitosis gene a)-related expressed kinase 6

GENE ID SPEZIES
59126 Mus musculus
497165 Danio rerio
417101 Gallus gallus
609003 Canis lupus familiaris
100514624 Sus scrofa
515816 Bos taurus
821634 Arabidopsis thaliana
10783 Homo sapiens
380346 Xenopus laevis
360161 Rattus norvegicus
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