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NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Zusätzlich bieten wir Ihnen N-Myc Downstream Regulated 1 Proteine (17) und N-Myc Downstream Regulated 1 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 198 products:
Human Polyclonal NDRG1 Primary Antibody für ICC, IF - ABIN4338332
Schilling, Hjelmeland, Radiloff, Liu, Wakeman, Fielhauer, Foster, Lathia, Rich, Wang, Datto: NDRG4 is required for cell cycle progression and survival in glioblastoma cells. in The Journal of biological chemistry 2009
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Human Monoclonal NDRG1 Primary Antibody für IF, IHC (p) - ABIN564518
Leth-Larsen, Lund, Hansen, Laenkholm, Tarin, Jensen, Ditzel: Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. in Molecular & cellular proteomics : MCP 2009
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Arabidopsis thaliana Polyclonal NDRG1 Primary Antibody für IHC - ABIN966642
Century, Shapiro, Repetti, Dahlbeck, Holub, Staskawicz: NDR1, a pathogen-induced component required for Arabidopsis disease resistance. in Science (New York, N.Y.) 1997
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Arabidopsis thaliana Polyclonal NDRG1 Primary Antibody für IHC - ABIN966641
Coppinger, Repetti, Day, Dahlbeck, Mehlert, Staskawicz: Overexpression of the plasma membrane-localized NDR1 protein results in enhanced bacterial disease resistance in Arabidopsis thaliana. in The Plant journal : for cell and molecular biology 2004
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Human Polyclonal NDRG1 Primary Antibody für IHC (p), IHC - ABIN268580
Zhou, Salnikow, Costa: Cap43, a novel gene specifically induced by Ni2+ compounds. in Cancer research 1998
Human Polyclonal NDRG1 Primary Antibody für IHC, IHC (p) - ABIN442051
Chaudhari, Talwar, Lefebvre Dhellencourt, Ravanan: CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells. in Frontiers in molecular neuroscience 1970
Human Polyclonal NDRG1 Primary Antibody für FACS, IHC (p) - ABIN390922
Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007
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These findings indicate that NDRG1 expression is associated with both prognosis and c-Myc (zeige MYC Antikörper) expression in lung adenocarcinoma
Meta-analysis showed that low NDRG1 expression was significantly associated with worse survival in colorectal cancer and pancreatic cancer but higher survival of patients with liver cancer and gallbladder cancer. No significant association was observed between low NDRG1 expression and survival in gastric cancer or esophageal cancer.
Findings indicate a positive feedback loop between cancer associated fibroblast (CAFs (zeige TBX1 Antikörper)) and box Q1 (FOXQ1 (zeige FOXQ1 Antikörper))/N-myc downstream-regulated gene 1 (NDRG1) axis in neoplastic cells to drive hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) initiation, suggesting new potential therapeutic targets for HCC (zeige FAM126A Antikörper).
In summary, CAPE attenuates Nasopharyngeal carcinoma (NPC (zeige NPC1 Antikörper))cell proliferation and invasion by upregulating NDRG1 expression via MAPK (zeige MAPK1 Antikörper) pathway and by inhibiting phosphorylation of STAT3 (zeige STAT3 Antikörper). Considering the poor prognosis of NPC (zeige NPC1 Antikörper) patients with metastasis, CAPE could be a promising agent against NPC (zeige NPC1 Antikörper).
These results indicate the N-terminus region and phosphorylation at Ser330 could be crucial for NDRG1 nuclear localization and function. PTEN silencing indicated that p-NDRG1 (Thr346) could be regulated differentially in different tumor cell-types, indicating PTEN may be involved in the mechanism(s) underlying the pleiotropic activity of NDRG1.
present study shows that HER4 and/or NDRG1 might play a critical role for the cell survival and chemo-resistance of Osteosarcoma (OS), and could be used as potential therapeutic targets in OS.
our study described two homozygous missense mutations in NDRG1 in CMT patients and mentioned the function of NDRG1 in protein recycling, which plays an important role in myelination of the peripheral nerve system.
NDRG1 over-expression promoted apoptosis in colorectal cancer cells whereas depletion of NDRG1 resulted in resistance to oxaliplatin treatment.
HCV coopts the MYC pathway responsible for NDRG1 expression and phosphorylation that regulates lipid droplet formation and metabolism. NDRG1 appears to restrict HCV by suppressing the lipid droplet formation that is necessary for HCV assembly.
these data show that NDRG1 is regulated by the oncogenic MAP kinase (zeige MAPK1 Antikörper)-interacting kinase pathway, a target for cancer therapy
NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors
NDR1 (zeige STK38 Antikörper) kinase, activated by the Rap1 (zeige TERF2IP Antikörper) signaling cascade through RAPL (zeige RASSF5 Antikörper) and Mst1 (zeige MST1 Antikörper)/Mst2 (zeige STK3 Antikörper), associated with and recruited kindlin-3 (zeige FERMT3 Antikörper) to the immunological synapses, which was required for high-affinity LFA-1 (zeige ITGAL Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) binding.
Snell, GHKRO, and PAPPA (zeige PAPPA Antikörper)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (zeige MGMT Antikörper)) and N-myc downstream-regulated gene 1 (NDRG1).
NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.
Using double knockout of NDR1 (zeige STK38 Antikörper) and 2 shows that NDRs acted downstream of MST1 (zeige MST1 Antikörper) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.
Ndrg1 is phosphorylated and degraded by CD28 (zeige CD28 Antikörper) signalling in a proteasome-dependent manner.
Ndr1 (zeige STK38 Antikörper)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (zeige STK38 Antikörper) kinases are critically required during the early phase of organogenesis
Rassf5 (zeige RASSF5 Antikörper) and Ndr1 (zeige STK38 Antikörper) or Ndr2 (zeige STK38L Antikörper) kinases regulate neuronal polarity through Par3 (zeige F2RL2 Antikörper) phosphorylation.
NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner
early growth response 1 (zeige EGR1 Antikörper), a transcription factor that binds to the NDRG1 promoter, was mediated in the NDRG1 expression regulation by PKD2 (zeige PKD2 Antikörper).
ndrg1b and fam49ab are 2 new modulators of PTEN signaling that control lymphoid differentiation in the zebrafish thymus.
NDR1 plays a broad role both in mediating primary cellular functions in Arabidopsis through maintaining the integrity of the cell wall-plasma membrane connection and as a key signaling component of these responses during pathogen infection.
SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.
The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.
Sequence analysis and mass spectrometry suggest that NDR1 (zeige STK38 Antikörper) is localized to the PM via a C-terminal glycosylphosphatidyl-inositol (GPI (zeige GPI Antikörper)) anchor.
demonstrate that the RIN4-NDR1 interaction occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is required for the activation of resistance signaling following infection by P. syringae
Mutations in NDR1 (zeige STK38 Antikörper) abolished the enhanced resistance of dnd (zeige DND1 Antikörper) mutants against Pseudomonas syringae pv. tomato and Hyaloperonospora parasitica but not Botrytis cinerea.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
N-myc downstream-regulated gene 1 protein
, differentiation-related gene 1 protein
, nickel-specific induction protein Cap43
, protein NDRG1
, protein regulated by oxygen-1
, reducing agents and tunicamycin-responsive protein
, N-myc downstream regulated 1
, protein Ndr1
, N-myc downstream regulated gene 1
, protein NDRG1-B
, protein NDRG1-like
, protein NDRG1-A
, N-myc downstream regulated gene 1, like
, N-myc downstream regulated gene 1b
, n-myc downstream-regulated gene 1b