Meprin A, beta (MEP1B) ELISA Kits

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. Zusätzlich bieten wir Ihnen Meprin B Antikörper (18) und Meprin B Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MEP1B 17288 Q61847
MEP1B 25727 P28826
MEP1B 4225 Q16820
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Top Meprin B ELISA Kits auf antikoerper-online.de

Showing 3 out of 16 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
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Maus
  96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$589.86
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Ratte
  96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$589.86
Details

Weitere ELISA Kits für Meprin B Interaktionspartner

Zebrafish Meprin A, beta (MEP1B) Interaktionspartner

Mouse (Murine) Meprin A, beta (MEP1B) Interaktionspartner

  1. Results provide evidence that meprin beta is involved in collagen deposition in vivo in the lung of bleomycin treated mice and it localized in region with immature collagen. This suggests that meprin beta can favor the progression of the fibrotic process enhancing collagen processing and deposition.

  2. This secreted cysteine protease (zeige CTSW ELISA Kits) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  3. no significant dentin malformation was observed in Mep1b (-/-) or Mep1a (zeige MEP1A ELISA Kits) (-/-) deficient mice.

  4. meprin alpha (zeige MEP1A ELISA Kits) and meprin beta join the modulators of Reelin (zeige RELN ELISA Kits) signalling as they cleave Reelin (zeige RELN ELISA Kits) at a specific site and are upregulated under specific pathological conditions.

  5. These studies provide strong evidence for a pathophysiological link between meprin beta and urinary excretion of cleaved nidogen-1 (zeige NID1 ELISA Kits) during cisplatin-induced acute kidney injury.

  6. While meprin A only cleaved protein kinase A (PKA) catalytic subunit beta1, meprin B cleaved all three PKA catalytic isoforms.

  7. Meprin beta is an endogenous zinc-dependent metalloprotease (zeige ADAMTS7 ELISA Kits) now shown to cleave the N-terminal region of the MUC2 (zeige MUC2 ELISA Kits) mucin (zeige SLC13A2 ELISA Kits) at two specific sites.

  8. Suggest role for in meprin-beta-Fra2 (zeige FOSL2 ELISA Kits) axis in mediating vascular remodelling in pulmonary hypertension.

  9. meprin alpha (zeige MEP1A ELISA Kits) and meprin beta are unique in their ability to process and release both C- and N-propeptides from type I procollagen (zeige COL1A2 ELISA Kits) in vitro and in vivo

  10. of the 151 new extracellular substrates identified, it was notable that ADAM10 (zeige ADAM10 ELISA Kits) the constitutive alpha-secretase-is activated by meprin beta through cleavage of the propeptide

Human Meprin A, beta (MEP1B) Interaktionspartner

  1. Results provide evidence that meprin beta is involved in collagen deposition in vivo in the lung of bleomycin treated mice and it localized in region with immature collagen. This suggests that meprin beta can favor the progression of the fibrotic process enhancing collagen processing and deposition.

  2. This secreted cysteine protease (zeige CTSB ELISA Kits) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  3. For meprin beta a reduction and for BMP-1 (zeige BMP1 ELISA Kits) an increase in activity was reported under increasing calcium concentrations.

  4. In this review we report on recent findings that summarize the complex molecular regulation of meprins, particular folding, activation and shedding. Dysregulation of meprin alpha (zeige MEP1A ELISA Kits) and meprin beta is often associated with pathological conditions such as neurodegeneration, inflammatory bowel disease and fibrosis

  5. TSPAN8 (zeige TSPAN8 ELISA Kits) might be important for the orchestration of meprin beta at the cell surface with impact on certain proteolytic processes

  6. n conclusion, we show that the concept of cleavable linkers specific for meprin beta is feasible, as the peptides are rapidly cleaved by the enzyme while retaining their biological properties

  7. Meprin Beta was found to be activated at the cell surface by matriptase-2 (zeige TMPRSS6 ELISA Kits).

  8. promotes inflammation in macrophages via ADAM-10 (zeige ADAM10 ELISA Kits) dependent pathway

  9. Overexpression of MEP1B is associated with pancreatic neuroendocrine tumors.

  10. Suggest role for in meprin-beta-Fra2 (zeige FOSL2 ELISA Kits) axis in mediating vascular remodelling in pulmonary hypertension.

Meprin B (MEP1B) Antigen-Profil

Beschreibung des Gens

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Genbezeichner und Symbole assoziert mit Meprin A, beta (MEP1B) ELISA Kits

  • meprin A subunit beta (MEP1B) Antikörper
  • meprin A subunit beta (LOC100031050) Antikörper
  • meprin A subunit beta (mep1b) Antikörper
  • meprin A, beta (mep1b) Antikörper
  • meprin A subunit beta (LOC100545010) Antikörper
  • meprin 1 beta (Mep1b) Antikörper
  • meprin A subunit beta (Mep1b) Antikörper
  • Mep-1b Antikörper
  • MEP1B Antikörper
  • si:ch211-191a24.6 Antikörper
  • zgc:153272 Antikörper

Bezeichner auf Proteinebene für Meprin A, beta (MEP1B) ELISA Kits

meprin A, beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta , meprin A subunit beta , meprin A subunit beta-like , endopeptidase-2 , meprin B , meprin beta , meprin A beta , N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit , PABA peptide hydrolase , PPH beta

GENE ID SPEZIES
421097 Gallus gallus
468515 Pan troglodytes
490497 Canis lupus familiaris
540701 Bos taurus
707036 Macaca mulatta
100031050 Monodelphis domestica
100124942 Xenopus (Silurana) tropicalis
100151009 Danio rerio
100406280 Callithrix jacchus
100461703 Pongo abelii
100474827 Ailuropoda melanoleuca
100516141 Sus scrofa
100545010 Meleagris gallopavo
100563868 Anolis carolinensis
100587715 Nomascus leucogenys
17288 Mus musculus
25727 Rattus norvegicus
4225 Homo sapiens
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