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may be involved in cartilage development [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen MIA Antikörper (58) und MIA Kits (13) und viele weitere Produktgruppen zu diesem Protein an.
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the molecular basis of the interaction of MIA with the Hep (zeige EPHB6 Proteine) II domain of fibronectin (zeige FN1 Proteine) based on nuclear magnetic resonance spectroscopic binding assays.
The frequency of MIA gene family expression was higher among squamous cell carcinomas than among other tumor types subjected to screening. MIA gene family staining was observed frequently in esophageal and lung cancers associated with nodal and/or distant metastasis. In cervical cancers, MIA and TANGO (zeige ARNT Proteine) immunostaining also correlated with tumor progression and metastasis.
Our results suggest that MIA-STOX2 signaling may be a useful diagnostic and therapeutic target in oral squamous cell carcinoma
MIA had a slightly superior sensitivity to detect progressive disease compared to S100 and seems to be more useful in monitoring of patients with metastatic melanoma receiving immunotherapy
real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B (zeige RAB4B Proteine) located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B (zeige RAB4B Proteine), the read-through long non-coding RNA (lncRNA), RAB4B (zeige RAB4B Proteine), PIM2 (zeige PIM2 Proteine) and TAOK1 (zeige TAOK1 Proteine) share common binding site of a microRNA, miR (zeige MLXIP Proteine)-24, in their 3'UTRs
The effects of MIA/CD-RAP on transcriptional regulation in chondrocytes, through the regulation of p54(nrb (zeige NONO Proteine)) via YBX1 (zeige YBX1 Proteine) contributes to the understanding of chondrogenesis.
data provide evidence for a critical role of SOX10 (zeige SOX10 Proteine) in melanoma cell invasion through the regulation of MIA and highlight its role as a therapeutic target in melanoma
Focus on the quantitative analysis of the MIA protein as a prognostic tool because it has proven to be a useful serum marker for documenting disease progression of malignant melanoma. Review.
Functional promoter analysis identified the transcription factor YBX1 (zeige YBX1 Proteine) as the mediator of MIA activation of p54(nrb (zeige NONO Proteine)) transcription.
MIA protein is present in non-segmental vitiligo (zeige MITF Proteine) skin and may cause the detachment of melanocytes; its target is integrin alpha5beta1, which determines the breaking and/or weakening of connections among melanocytes and basal membrane
Attenuated LM expressing MIA.
as observed in other knockout models of molecules important for cartilage development and differentiation, viability and functional integrity is reached by remarkable molecular redundancy in MIA/CD-RAP knockout mice.
The cartilage protein melanoma inhibitory activity contributes to inflammatory arthritis.
Expression analysis of cartilage tissue derived from MIA-/- mice revealed strong downregulation of nuclear RNA-binding protein 54-kDa.
MIA/CD-RAP stabilizes cartilage differentiation and inhibits differentiation into bone potentially by regulating signaling processes during differentiation.
transcriptional mechanism by which CD-RAP expression is suppressed by IL-1 beta (zeige IL1B Proteine)
Cdrap/Mia is located between two housekeeping genes
DNA promoter segment from -2,251 bp to -2,068 bp of the CD-RAP gene contains elements critical for gene expression. It demonstrates activation or repression of gene expression in vitro and in vivo based on cell type and content of transcription factors.
A potential tumor suppressor role of Mia/Cd-rap in pituitary cells.
may be involved in cartilage development
melanoma-derived growth regulatory protein
, melanoma inhibitory activity 1
, melanoma inhibitory activity protein
, cartilage derived retinoic acid sensitive protein
, cartilage-derived retinoic acid-sensitive protein
, melanoma inhibitory activity/condrocyte-derived retinoic acid sensitive protein homolog (MIA/CD-RAP)
, melanoma inhibitory activity-like
, Melanoma-derived growth regulatory protein