anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) Antikörper

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Zusätzlich bieten wir Ihnen MARK1 Proteine (6) und MARK1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MARK1 226778 Q8VHJ5
MARK1 117016 O08678
MARK1 4139 Q9P0L2
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Top anti-MARK1 Antikörper auf antikoerper-online.de

Showing 10 out of 157 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of MARK staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 bis 14 Tage
$487.50
Details
Maus Ziege Unkonjugiert ELISA   100 μg 6 bis 7 Tage
$291.53
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using MARK Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. The anti-MARK1 N-term Pab is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 pab was used. 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, WB The anti-MARK1 C-term Pab is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. 0.4 mL 6 bis 8 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-MARK1 antibody  ABIN1049038 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Human Brain, Caduate (formalin-fixed, paraffin-embedded) stained with MARK1 antibody ABIN239802 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Pferd Kaninchen Unkonjugiert IHC, IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MARK1 antibody ABIN239803 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p) 50 μg 12 bis 14 Tage
$686.14
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using MARK antibody.The lane on the left is treated with the antigen-specific peptide. Western blot analysis of MARK expression in various lysates 100 μL 11 bis 12 Tage
$390.77
Details

Am meisten referenzierte anti-MARK1 Antikörper

  1. Human Polyclonal MARK1 Primary Antibody für IHC (p), ELISA - ABIN543660 : Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. in Molecular and cellular biology 2008 (PubMed)

  2. Mouse (Murine) Polyclonal MARK1 Primary Antibody für ELISA - ABIN548084 : Marx, Nugoor, Müller, Panneerselvam, Timm, Bilang, Mylonas, Svergun, Mandelkow, Mandelkow: Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2. in The Journal of biological chemistry 2006 (PubMed)

Weitere Antikörper gegen MARK1 Interaktionspartner

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) Interaktionspartner

  1. In vitro kinase assays and metabolic-labeling experiments in living cells confirmed MARK1 as an LRRK2 substrate. Moreover, we also showed that LRRK2 and MARK1 are interacting in eukaryotic cells.

  2. Overexpression and silencing of MARK1 resulted in significantly shorter dendrite length in mouse neocortical neurons and modified dendritic transport speed.

Human MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) Interaktionspartner

  1. Structural basis for MARK1 kinase autoinhibition by its KA1 domain has been uncovered.

  2. Low MARK1 is associated with cervical cancer.

  3. Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase have been described.

  4. the positioning of MARK/Par-1 at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]

  5. LKB1 acts through its substrates of the microtubule affinity-regulating kinase family to regulate the localization of the polarity determinant Scribble and the activity of the core Hippo kinases

  6. In the Australian GWAS, the SNP rs7530302 near MARK1 on chromosome 1 (p=1.90 x 10(-9) achieved genomewide significance for comorbid AD/ND.

  7. analysis of variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2

  8. MARK1 was overexpressed in a prefrontal region in the brains of patients with Autism spectrum disorders.

  9. Data show that protein kinases of the MARK family phosphorylate tau protein in its repeat domain and thereby regulate its affinity for microtubules and affect the aggregation of tau into Alzheimer paired helical filaments.

MARK1 Antigen-Profil

Protein Überblick

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).

Genbezeichner und Symbole assoziert mit MARK1

  • MAP/microtubule affinity-regulating kinase 1 S homeolog (mark1.S) Antikörper
  • microtubule affinity regulating kinase 1 (MARK1) Antikörper
  • MAP/microtubule affinity-regulating kinase 1 (mark1) Antikörper
  • microtubule affinity regulating kinase 1 (mark1) Antikörper
  • MAP/microtubule affinity regulating kinase 1 (Mark1) Antikörper
  • microtubule affinity regulating kinase 1 (Mark1) Antikörper
  • AW491150 Antikörper
  • B930025N23Rik Antikörper
  • Emk3 Antikörper
  • MARK Antikörper
  • MARK1 Antikörper
  • MGC80341 Antikörper
  • mKIAA1477 Antikörper
  • mPar-1c Antikörper
  • Par-1c Antikörper
  • Par1c Antikörper

Bezeichner auf Proteinebene für MARK1

MAP/microtubule affinity-regulating kinase 1 , chemokine CCL-CUc , serine/threonine-protein kinase MARK1 , serine/threonine-protein kinase MARK1-like , ELKL motif serine-threonine protein kinase 3 , ELKL motif serine/threonine-protein kinase 3 , PAR1 homolog c

GENE ID SPEZIES
432201 Xenopus laevis
469683 Pan troglodytes
100003170 Danio rerio
100456064 Pongo abelii
100559635 Anolis carolinensis
226778 Mus musculus
117016 Rattus norvegicus
4139 Homo sapiens
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