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LILRA4 encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs).
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Human Monoclonal LILRA4 Primary Antibody für Func, FACS - ABIN1176952
Cao, Bover, Cho, Wen, Hanabuchi, Bao, Rosen, Wang, Shaw, Du, Li, Arai, Yao, Lanier, Liu: Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. in The Journal of experimental medicine 2009
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Human Monoclonal LILRA4 Primary Antibody für FACS - ABIN4896750
Leng, Chou, Scaria, Woodle, Mixson: Buffering capacity and size of siRNA polyplexes influence cytokine levels. in Molecular therapy : the journal of the American Society of Gene Therapy 2012
Crosslinked ILT7 favours the differentiation of immature plasmacytoid dendritic cells into antigen-presenting cells rather than IPC.
ILT7 may exert its immunomodulatory activity only on immature circulating plasmacytoid dendritic cells (pDCs), providing a basic homeostatic mechanism rather than negative feedback control on activated pDCs.
Intracellular expression of the TCL1 (zeige TCL1A Antikörper) as well as membrane and intracellular expression of ILT7 in plasmacytoid dendritic cell leukemia (pDCL (zeige PDCL Antikörper)) samples and 61 non-pDC (zeige PNKD Antikörper) acute leukemia samples, were tested.
the expression of immunoglobulin-like transcript 7, in plasmacytoid dendritic cells
ILT7 protein associates with the signal adapter protein (zeige TOLLIP Antikörper) Fc epsilonRI gamma to form a receptor complex in dendritic cells.
key regulator of human pDC (zeige PNKD Antikörper) function and interferon (zeige IFNA Antikörper) type I production.
Data show that BST2 (zeige BST2 Antikörper) directly binds to purified ILT7, initiates signaling via the ILT7-FcepsilonRIgamma complex, and regulates TLR7 (zeige TLR7 Antikörper)/9 responses in plasmacytoid dendritic cells.
This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4.
leukocyte immunoglobulin-like receptor subfamily A member 4
, immunoglobulin-like transcript 7
, CD85 antigen-like family member G
, leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4