Jerky Homolog (Mouse) Proteine (JRK)

JRK is the human homolog of the mouse jerky gene. Zusätzlich bieten wir Ihnen JRK Antikörper (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID
JRK 8629
JRK 16469
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details

JRK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Jerky Homolog (Mouse) (JRK) Interaktionspartnern

Human Jerky Homolog (Mouse) (JRK) Interaktionspartner

  1. JRK (zeige CLOCK Proteine) expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin (zeige CTNNB1 Proteine) target genes and increased cell proliferation

  2. in the adult intestine, Ebd (zeige DEFB1 Proteine) acts independently of Ewg in physiological Wnt (zeige WNT2 Proteine) signaling, but cooperates with Ewg to induce the hyperactivation of Wnt (zeige WNT2 Proteine) target gene expression following Apc1 (zeige SLC25A24 Proteine) loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd (zeige DEFB1 Proteine) homolog, promotes Wnt (zeige WNT2 Proteine) pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers

Mouse (Murine) Jerky Homolog (Mouse) (JRK) Interaktionspartner

  1. Jerky has a role in epilepsy and consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs

  2. JRK protein associates with a specific chromosomal centromeric locus in the cell cycle G(2) phase.

JRK Protein Überblick

Protein Überblick

This gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, suggesting that it might function as a DNA-binding protein. Insertional inactivation of this gene in transgenic mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene, making this gene a strong candidate for CAE. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Jerky Homolog (Mouse) Proteine (JRK)

  • Jrk helix-turn-helix protein (JRK)
  • jerky (Jrk)
  • JH8 Protein

Bezeichner auf Proteinebene für Jerky Homolog (Mouse) Proteine (JRK)

jerky protein homolog , jerky protein

GENE ID SPEZIES
8629 Homo sapiens
16469 Mus musculus
Ausgewählte Anbieter für JRK Proteine (JRK)
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