Homer Homolog 3 (Drosophila) Proteine (HOMER3)

HOMER3 encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. Zusätzlich bieten wir Ihnen HOMER3 Antikörper (74) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HOMER3 9454 Q9NSC5
HOMER3 26558 Q99JP6
Ratte HOMER3 HOMER3 29548 Q9Z2X5
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Showing 5 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
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HOMER3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Homer Homolog 3 (Drosophila) (HOMER3) Interaktionspartnern

Human Homer Homolog 3 (Drosophila) (HOMER3) Interaktionspartner

  1. Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation.

  2. Interaction of the protein with amyloid precursor protein (zeige APP Proteine) is regulated by calcium homeostasis.

  3. Loss of Homer3 is associated with acute myeloid leukemia (zeige BCL11A Proteine).

  4. Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta (zeige IKBKB Proteine) subunit (zeige POLG Proteine) of the IKK (zeige CHUK Proteine) complex.

  5. Homer-3 may be involved in the regulation of SRE activation in T cells via interaction between its EVH1 domain and C/EBP beta (zeige CEBPB Proteine).

  6. Fat1 exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells

  7. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin

Mouse (Murine) Homer Homolog 3 (Drosophila) (HOMER3) Interaktionspartner

  1. impaired mTORC1-Homer-3 activity underlies PC susceptibility in Spinocerebellar ataxia type 1 and presents a promising therapeutic target

  2. Expression of Homer (zeige HOMER1 Proteine) 3a/b is restricted to the developing cerebellum, hippocampus, and neonatal olfactory bulb, and is concentrated in the dendritic spines of Purkinje cells and their axons.

  3. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin

  4. Homer2 (zeige HOMER2 Proteine) and Homer3 proteins interact specifically with amyloid precursor protein (APP (zeige APP Proteine)) by inhibiting APP (zeige APP Proteine) processing and reducing secretion of Abeta (zeige APP Proteine) peptides.

  5. Homer3 in Purkinje cells might function as a reversible coupler regulated by CaMKII (zeige CAMK2G Proteine) phosphorylation and that the phosphorylation is capable of regulating the postsynaptic molecular architecture in response to synaptic activity.

HOMER3 Protein Überblick

Protein Überblick

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit HOMER3

  • homer scaffolding protein 3b (homer3b)
  • homer scaffolding protein 3 (HOMER3)
  • homer scaffolding protein 3 (Homer3)
  • AW146114 Protein
  • HOMER-3 Protein
  • Vesl-3 Protein
  • VESL3 Protein
  • zgc:55557 Protein

Bezeichner auf Proteinebene für HOMER3

homer protein homolog 3 , Homer, neuronal immediate early gene, 3 , homer homolog 3 (Drosophila) , homer, neuronal immediate early gene, 3 , homer-3 , VASP/Ena-related gene up-regulated during seizure and LTP 3

GENE ID SPEZIES
394088 Danio rerio
736171 Pan troglodytes
100605039 Nomascus leucogenys
9454 Homo sapiens
26558 Mus musculus
29548 Rattus norvegicus
420115 Gallus gallus
484813 Canis lupus familiaris
508124 Bos taurus
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