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HOXB13 encodes a transcription factor that belongs to the homeobox gene family. Zusätzlich bieten wir Ihnen HOXB13 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 72 products:
Human Polyclonal HOXB13 Primary Antibody für ELISA, WB - ABIN251694
Zhao, Yamashita, Ishikawa: Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer. in Oncology reports 2005
Guinea Pig Polyclonal HOXB13 Primary Antibody für WB - ABIN2779853
Kondrashov, Pusic, Stumpf, Shimizu, Hsieh, Xue, Ishijima, Shiroishi, Barna: Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. in Cell 2011
Cdx (zeige CDX1 Antikörper) and Wnt (zeige WNT2 Antikörper) mutations and premature Hox13 (zeige HOXA5 Antikörper) expression also cause similar neural dysmorphology
Hoxb13 has a negative effect on skin wound repair
Data demonstrate that FOXA1 directly regulates HOXB13 in human prostate epithelial cells, and show that this prostate-specific regulatory mechanism is conserved in mice.
results suggest a specific role for Hoxb13 in a differentiation pathway that gives the ventral prostate epithelium a unique identity, as well as a more general role in ventral prostate morphogenesis that is redundant with other Hox13 (zeige HOXA5 Antikörper) paralogs
Hoxb13 knockout mice exhibit enhanced cutaneous wound healing.
Epidermal HOXB13 signal was detected over the entire body surface, but surprisingly, essentially all of the signal was cytoplasmic in developing skin
An increase of the Ala repeat above a certain length (22 Ala)in the Hoxd13 (zeige HOXD13 Antikörper) sequence, resulting in synpolydactyly, is associated with a shift in the localization of Hox13 (zeige HOXA5 Antikörper) from nuclear to cytoplasmic and aggregation.
Hoxb13 cis (zeige CISH Antikörper)-regulatory elements provide a powerful tool to achieve androgen-independent transgene expression in the prostate and distal colon-specific expression in the gastrointestinal tract
none of the recurrent HOXB13 mutations that were identified in the Dutch population were associated with breast cancer risk, although it may be worthwhile to evaluate p.R217C in a larger study or a population with a higher allele frequency.
our results indicated that the G84E mutation in HOXB13 gene might increase susceptibility to prostate cancer
HOXB13 mutation is associated with prostate tumors.
CCAT1 regulates HOXB13 as a molecular decoy for miR-7 (zeige LILRB1 Antikörper), a microRNA that targets both CCAT1 and HOXB13, thus facilitating cell growth and migration in esophageal squamous cell carcinoma
This study presents in silico prediction approaches of the deleterious ns single nucleotide polymorphisms (missense) in the homeobox (zeige Lbx1 Antikörper) domain of human HOXB13 gene responsible for hereditary prostate cancer.
This is the first study to investigate the HOXB13 G84E mutation in Danish men. The mutation was detected in 0.49% of controls and in 2.51% of cases, and was associated with 5.12-fold increased relative risk of being diagnosed with prostate cancer. In our RP cohort, HOXB13 mutation carriers were more likely to develop aggressive prostate cancer.
HOXB13 is a useful marker for prostate origin when doubt exists regarding the site of the primary of a metastatic lesion
Tumor-associated macrophage-secreted CXCL8 (zeige IL8 Antikörper) downregulated the ERalpha (zeige ESR1 Antikörper) expression of endometrial cancer cells via HOXB13, which may be associated with cancer invasion, metastasis and poor prognosis.
Study provides insights suggesting that HOXB13 plays an important role in prostate tumorigenesis and malignant progression via the regulation of both p21 (zeige CDKN1A Antikörper) and JNK (zeige MAPK8 Antikörper) signaling.
The Breast Cancer Index (BCI) is a continuous risk index model of two previously described biomarkers: molecular grade index (MGI) and HOXB13:IL17BR (H:I) ratio
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.
, homeo box B13
, homeobox protein Hox-B13