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The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum.
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Human GOLM1 ELISA Kit für Sandwich ELISA - ABIN414786
Kosanam, Prassas, Chrystoja, Soleas, Chan, Dimitromanolakis, Blasutig, Rückert, Gruetzmann, Pilarsky, Maekawa, Brand, Diamandis: Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues. in Molecular & cellular proteomics : MCP 2013
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serum GP73 is an accurate serum marker for significant fibrosis in chronic HBV infection, with higher accuracy than APRI and FIB (zeige FBL ELISA Kits)-4. Serum GP73 is potentially a complementary tool for TE when evaluating the necessity of antiviral treatment, particularly in patients without definite antiviral indication.
The detection of ALT, AFP (zeige AFP ELISA Kits), AFP (zeige AFP ELISA Kits)-L3, and GP73 has a certain guiding significance to predict the risk of hepatocellular carcinoma in hepatic cirrhosis patients
The mechanism of hepatocarcinogenesis and a promising blueprint for miR-493-5p-GP73 axis-oriented treatment of HCC.
GP73 unglycosylation is associated with hepatocellular carcinoma cell motility and invasiveness.
The GOLPH2 is a novel marker for non-small-cell lung cancer.
Findings suggest that GP73 silencing through siRNA delivery may provide a low-toxicity therapy for the inhibition of tumor proliferation and metastasis.
Both gain- and loss-of-function studies determine that GOLM1 acts as a key oncogene by promoting HCC growth and metastasis.
A cytokine QTL at the NAA35-GOLM1 locus markedly modulated interleukin (IL)-6 (zeige IL6 ELISA Kits) production in response to multiple pathogens and was associated with susceptibility to candidemia.
knock-down of GP73 down-regulates HCV infection and replication in Huh7-MAVSR cells and primary human hepatocytes
Studies indicate that golgi membrane protein 1 (GOLM1) may promote HCC by regulation of epidermal growth factor receptor (EGFR (zeige EGFR ELISA Kits)) recycling, and suggest that therapeutic targeting of GOLM1 may be a potential strategy for combating hepatocellular carcinoma (HCC) metastasis.
In Atp7b (zeige ATP7B ELISA Kits)(-/-) mice, GP73 mRNA was significantly elevated at 20-46 weeks of age, coincident with extensive hepatic inflammation and fibrosis.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.
Golgi membrane protein 1
, golgi membrane protein GP73
, golgi phosphoprotein 2
, golgi protein, 73-kD
, golgi membrane protein 1