Glycophorin B (MNS Blood Group) Proteine (GYPB)

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. Zusätzlich bieten wir Ihnen Glycophorin B (MNS Blood Group) Antikörper (36) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GYPB 2994 P06028
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Top Glycophorin B (MNS Blood Group) Proteine auf

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 11 bis 12 Tage

GYPB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Weitere Proteine zu Glycophorin B (MNS Blood Group) (GYPB) Interaktionspartnern

Human Glycophorin B (MNS Blood Group) (GYPB) Interaktionspartner

  1. A novel c.166A>T (p.Thr56Ser) mutation in GYPB*S decreases S antigen expression.

  2. a complex structural rearrangement involving the loss of GYPB and gain of two GYPB-A hybrid genes reduces the risk of severe malaria by 40% and has recently increased in frequency in parts of Kenya

  3. through bioinformatic analysis, identified extensive variation in GYPB transcript levels in individuals from Benin, suggesting selection from malaria pressure; collective data suggest that the GPA and GPB receptors are of greater importance than the GPC receptor, supporting a hierarchy of erythrocyte receptor usage in P. falciparum

  4. MNSs blood group glycophorin variants in Taiwan: a genotype-serotype correlation study of 'Mi(a)' and St(a) with report of two new alleles for St(a).

  5. A novel GYPB mutation (c.270+5G>A) accounting for the S-s-U+(var) phenotype was identified.

  6. Substitution of GPB with Gp.Mur significantly reduced the expression of Rh antigen and RhAG on the Mi.III(+/+) erythrocyte membrane

  7. an increased susceptibility to infection by this parasite is associated with the glycophorin B S+ variant in Brazilian Amazons

  8. Indochina I strain of P. falciparum is not dependent on glycophorin B to invade erythrocytse through a trypsin-resistant pathway as are the strains 3D7, HB3, and Dd2.

  9. The S-s-U+var phenotype arises from changes in or around GYPB exon 5.

  10. GYPA & GYPB genotypes carrying MNSs antigens were analyzed in Thai patients with cerebral malaria & mild malaria; no statistical difference was found; it is concluded that MNSs antigens do not reveal the difference in susceptibility to cerebral malaria

  11. Alternative to conventional tube technique for mass screening for MNS hybrids, especially when specific antisera are not available.

  12. Immunoblotting showed the presence of monomer and dimer forms of a GP(A-B) hybrid and an absence of GPA and GPB. Sequencing of DNA and PCR-RFLP using the restriction enzyme RsaI confirmed the presence of a hybrid GYP(AB).

  13. The erythrocyte-binding domain, region 2 of EBL-1, bound glycophorin B(+) but

  14. This study reports for the first time the molecular mechanisms responsible for the S-s- phenotype in a population of African Brazilians and provides new information about the frequency and molecular bases of the GYPB*S silent gene in this population.

Glycophorin B (MNS Blood Group) (GYPB) Protein Überblick

Protein Überblick

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta\\\\; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.

Genbezeichner und Symbole assoziert mit GYPB

  • glycophorin B (MNS blood group) (GYPB)
  • CD235b Protein
  • GPB Protein
  • GPB.NY Protein
  • GpMiIII Protein
  • GYPHe.NY Protein
  • HGpMiIII Protein
  • HGpMiVI Protein
  • HGpMiX Protein
  • MNS Protein
  • PAS-3 Protein
  • SS Protein

Bezeichner auf Proteinebene für GYPB

SS-active sialoglycoprotein , Ss blood group , glycophorin HeP2 , glycophorin MiIII , glycophorin MiVI , glycophorin MiX , glycophorin-B , sialoglycoprotein delta

2994 Homo sapiens
Ausgewählte Anbieter für Glycophorin B (MNS Blood Group) Proteine (GYPB)
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