Glycine Dehydrogenase Proteine (GLDC)

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Zusätzlich bieten wir Ihnen Glycine Dehydrogenase Antikörper (70) und Glycine Dehydrogenase Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GLDC 104174 Q91W43
GLDC 2731 P23378
GLDC 309312  
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Top Glycine Dehydrogenase Proteine auf antikoerper-online.de

Showing 7 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$858.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Maus T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
Details
Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
Details

GLDC Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
,
Human , ,
,
Rat (Rattus)

Weitere Proteine zu Glycine Dehydrogenase (GLDC) Interaktionspartnern

Mouse (Murine) Glycine Dehydrogenase (GLDC) Interaktionspartner

  1. Exencephaly and ventriculomegaly were detectable by High-frequency ultrasound in homozygous Gldc-deficient mouse embryos indicating this to be an effective tool to study CNS development.

  2. These studies support a direct relationship between p53 (zeige TP53 Proteine) mutations and GLDC expression in B cell lymphoma.

  3. Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice through limiting supply of one-carbon units from mitochondrial folate metabolism.

  4. Results suggest that there is a direct correlation between ischemic injury and extracellular glycine concentration maintained by glycine decarboxylase and the glycine cleavage multienzyme system.

Human Glycine Dehydrogenase (GLDC) Interaktionspartner

  1. a comprehensive functional and structural analysis of 19 GLDC missense variants identified in a cohort of 26 nonketotic hyperglycinemia patients was performed

  2. The position and frequency of the breakpoint for CNVs correlated with intron size and presence of Alu elements. Missense mutations, most often recurring, were the most common type of disease-causing mutation in AMT (zeige AMT Proteine)

  3. We show that the combination of GLDC and HIF-1alpha (zeige HIF1A Proteine) expression is an independent prognostic factor in early-stage lung non-small cell cancer

  4. Data indicate no mutation was found in glycine cleavage system protein-H (zeige GCSH Proteine) (GCSH (zeige GCSH Proteine)) and suggest that mutations in both glycine decarboxylase (GLDC) and aminomethyltransferase (AMT (zeige AMT Proteine)) are the main cause of glycine encephalopathy in Malaysian population.

  5. study reports a novel mutation, c.2296G>T (p.Gly766Cys), in exon 19 of the glycine decarboxylase (GLDC) gene in a consanguineous Indian couple with a history of 4 neonatal deaths

  6. Identification of a splice acceptor site mutation and five different non-synonymous variants in GLDC were found in patients with neural tube defects.

  7. Study shows that glycine metabolism and the metabolic enzyme glycine decarboxylase (GLDC) drive tumor-initiating cells and tumorigenesis in non-small cell lung cancer.

  8. Heterozygous GLDC gene mutation in transient neonatal hyperglycinemia.

  9. Three adults with mild hyperglycinemia, infantile hypotonia, mental retardation, behavioral hyperirritability, and aggressive outbursts were screened for glycine decarboxylase mutations; two novel missense mutations were found.

  10. The mutation in this nonketotic hyperglycinemia kindred led to missplicing and reduced GLDC (glycine decarboxylase) expression.

Glycine Dehydrogenase (GLDC) Protein Überblick

Protein Überblick

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Genbezeichner und Symbole assoziert mit Glycine Dehydrogenase Proteine (GLDC)

  • glycine dehydrogenase (decarboxylating) GcvP (gcvP)
  • glycine dehydrogenase (gcvP)
  • glycine dehydrogenase (Tb927.7.1910)
  • glycine cleavage system P-protein (gcvP)
  • glycine decarboxylase (Gldc)
  • glycine decarboxylase (GLDC)
  • glycine dehydrogenase (decarboxylating) (gldc)
  • glycine decarboxylase S homeolog (gldc.S)
  • D030049L12Rik Protein
  • D19Wsu57e Protein
  • DDBDRAFT_0219205 Protein
  • DDBDRAFT_0231130 Protein
  • DDB_0219205 Protein
  • DDB_0231130 Protein
  • fb23b05 Protein
  • GCE Protein
  • GCSP Protein
  • gldc Protein
  • HYGN1 Protein
  • PSPTO1276 Protein
  • Tb07.43M14.350 Protein
  • wu:fb23b05 Protein
  • zgc:66198 Protein

Bezeichner auf Proteinebene für Glycine Dehydrogenase Proteine (GLDC)

glycine dehydrogenase , glycine cleavage system P protein , glycine dehydrogenase [decarboxylating], mitochondrial , glycine cleavage system protein P , glycine decarboxylase P-protein , glycine cleavage system protein P) , glycine decarboxylase , glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P) , glycine decarboxylase, glycine cleavage system protein P) , glycine dehydrogenase (decarboxylating), mitochondrial , glycine decarboxylase S homeolog , glycine dehydrogenase (decarboxylating) S homeolog

GENE ID SPEZIES
1168636 Shewanella oneidensis MR-1
1182912 Pseudomonas syringae pv. tomato str. DC3000
3196586 Ruegeria pomeroyi DSS-3
3658401 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8626028 Dictyostelium discoideum AX4
104174 Mus musculus
2731 Homo sapiens
374222 Gallus gallus
309312 Rattus norvegicus
481534 Canis lupus familiaris
321621 Danio rerio
379833 Xenopus laevis
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