Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) ELISA Kits

GAD2 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. Zusätzlich bieten wir Ihnen GAD65 Antikörper (220) und GAD65 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GAD2 24380 Q05683
GAD2 2572 Q05329
GAD2 14417 P48320
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Top GAD65 ELISA Kits auf antikoerper-online.de

Showing 8 out of 41 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$910.56
Details
Ratte 1.17 pg/mL 4.68-300 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Maus
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Huhn 0.469 ng/mL 0.781-50 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Kaninchen 0.375 ng/mL 0.625-40 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Schwein 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Affe 0.469 ng/mL 0.781-50 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Hund
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
Details

Weitere ELISA Kits für GAD65 Interaktionspartner

Rhesus Monkey Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) Interaktionspartner

  1. Results describe the gross distribution patterns of GAD65 in human and rhesus monkey thalami and show that they are nearly identical.

Zebrafish Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) Interaktionspartner

  1. GAD65 mRNA was found in the periaqueductal gray.

Human Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) Interaktionspartner

  1. This study showed a significant 58% increase of SCN (zeige SRI ELISA Kits) GAD65/67-ir and a significant 169% increase of SCN (zeige SRI ELISA Kits) GAD67 (zeige GAD1 ELISA Kits)-mRNA in the depression group.

  2. healthy donor NK cells showed similar degranulation against both GAD65 AA 114-122 pulsed and unpulsed APCs (zeige APCS ELISA Kits). The pathogenetic significance of the CD3 (zeige CD3 ELISA Kits)-CD8dullCD56+ 'memory-like NK cell subset' with increased response upon secondary challenge in diabetics remains to be elucidated

  3. Genetic variability in GAD2 and GAD1 (zeige GAD1 ELISA Kits) contributes to risk of methamphetamine dependence in the Thai population.

  4. Study propose that aberrant accumulation of immunogenic GAD65 in Golgi membranes facilitates inappropriate presentation to the immune system after release from stressed and/or damaged beta-cells, triggering autoimmunity.

  5. UV exposed hydrogen peroxide produces hydroxyl radical that may cause protein damage (GAD-65) to the extent of generating neo-epitopes on the molecule, making it immunogenic.

  6. we investigated the relationship between serum glutamic acid decarboxylase (GAD (zeige GAD ELISA Kits)) autoantibody (Ab) levels and single nucleotide polymorphisms (SNPs) of the glutamic acid de-carboxylase 2 (GAD2) 5'-untranslated region

  7. GAD (zeige GAD1 ELISA Kits) autoantibodies were associated with risk of developing type 1 diabetes.

  8. Kaplan-Meier survival curves estimated a worst pancreas graft survival for patients with positive IA-2 (zeige PTPRN ELISA Kits) antibodies versus those patients with negative auto-antibodies and GAD65+ auto-antibodies after simultaneous pancreas kidney transplantation.

  9. Plasma GAD65 qualifies as a marker for early beta-cell loss after intraportal transplantation.

  10. Cohort study shows that mean GAD65 mRNA levels in the prefrontal cortex area 9 are not altered in subjects with schizophrenia but are lower in subjects with schizoaffective disorder

Mouse (Murine) Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) Interaktionspartner

  1. These results thus identify a molecularly distinct, orexin (zeige OX ELISA Kits)-activated lateral hypothalamus submodule that governs physical activity in mice.

  2. Results suggest age-dependent decrease of GAD65/67 mRNAs but normal densities of certain GABAergic interneurons in the Shank3 (zeige SHANK3 ELISA Kits) transgenic mice.

  3. GABA is the major inhibitory neurotransmitter in the brain. We show that Dlx1/Dlx2 homeobox (zeige PRRX1 ELISA Kits) genes regulate GABA synthesis during forebrain development through direct activation of glutamic acid decarboxylase (zeige GAD ELISA Kits) enzyme isoforms that convert glutamate (zeige GRIN1 ELISA Kits) to GABA.

  4. Treadmill running prevented partial sciatic nerve ligation-induced reductions in GAD65/67 production, and, thus, GABA levels may be retained in interneurons and neuropils in the superficial dorsal horn.

  5. Increased activity due to bicuculline preferentially up-regulated GAD65. This was reduced by AP5, a selective blocker of Ca2 (zeige CA2 ELISA Kits)+-permeable ion channels and NMDA-Rs, and by U0126, KN93, and K252a, affecting BDNF (zeige BDNF ELISA Kits) pathways.

  6. Data show that miRNAs are involved in regulating the expression of the major type 1 diabetes (T1D) autoantigens IA-2 (zeige PTPRN ELISA Kits), IA-2beta (zeige PTPRN2 ELISA Kits), and GAD65 enzyme.

  7. Results indicate the significant contribution of not only GAD65, GAD67 (zeige GAD1 ELISA Kits) and VGAT (zeige SLC32A1 ELISA Kits)-mediated GABAergic but also glycinergic transmissions to both palate and abdominal wall formations

  8. Analysis of GAD65/67 single and double knock-out embryos revealed that the two GADs play complementary (inhibitory) roles in GnRH migration ultimately modulating the speed and/or direction of GnRH migration.

  9. Results show that GAD65 is required for efficient GABAergic synaptic transmission and plasticity, and for maintaining extracellular GABA at a level needed for associative plasticity at cortical inputs in the lateral amygdala

  10. Menin regulates spinal glutamate (zeige GRIN1 ELISA Kits)-GABA balance through GAD65 contributing to neuropathic pain.

GAD65 (GAD2) Antigen-Profil

Beschreibung des Gens

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit GAD2

  • glutamate decarboxylase 2 (GAD2) Antikörper
  • glutamate decarboxylase 2 (PTRG_06148) Antikörper
  • glutamate decarboxylase 2 (LOC9324534) Antikörper
  • glutamate decarboxylase 2 (Gad2) Antikörper
  • glutamate decarboxylase 1 (GAD1) Antikörper
  • glutamate decarboxylase 2 (gad2) Antikörper
  • glutamic acid decarboxylase 2 (Gad2) Antikörper
  • 6330404F12Rik Antikörper
  • F12P19.12 Antikörper
  • F12P19_12 Antikörper
  • GAD(65) Antikörper
  • Gad-2 Antikörper
  • gad65 Antikörper
  • glutamate decarboxylase 2 Antikörper
  • zgc:112198 Antikörper

Bezeichner auf Proteinebene für GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) , glutamate decarboxylase 2 , glutamic acid decarboxylase , 65 kDa glutamic acid decarboxylase , GAD-65 , Glutamate decarboxylase 2 (islet) , glutamate decarboxylase 65 kDa isoform , glutamic acid decarboxylase 2 , glutamic acid decarboxylase 65 , Glutamate decarboxylase-2 (pancreas)

GENE ID SPEZIES
466026 Pan troglodytes
512459 Bos taurus
613029 Macaca mulatta
4836947 Scheffersomyces stipitis CBS 6054
6344405 Pyrenophora tritici-repentis Pt-1C-BFP
9324534 Arabidopsis lyrata subsp. lyrata
24380 Rattus norvegicus
100344727 Oryctolagus cuniculus
842908 Arabidopsis thaliana
550403 Danio rerio
2572 Homo sapiens
487107 Canis lupus familiaris
395395 Gallus gallus
396929 Sus scrofa
14417 Mus musculus
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