anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) Antikörper

GDAP1 encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Zusätzlich bieten wir Ihnen GDAP1 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GDAP1 54332 Q8TB36
GDAP1 14545 O88741
GDAP1 312890  
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Top anti-GDAP1 Antikörper auf antikoerper-online.de

Showing 10 out of 38 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: GDAP1 Antibody [NBP1-84429] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Immunohistochemistry-Paraffin: GDAP1 Antibody  - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDAP1 Antibody [NBP1-84430] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: GDAP1 Antibody [NBP1-84430] - Staining of human cell line A549 shows positivity in cytoplasm & mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using GDAP1 antibody (ABIN5973967) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody (ABIN5973967) at dilution of 1/100 (40x lens). 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Human Maus Unkonjugiert ELISA, WB GDAP1 polyclonal antibody (A01), Lot # 060613JCS1 Western Blot analysis of GDAP1 expression in HepG2 . Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details
Human Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Fledermaus Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using GDAP1 antibody. Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody. 100 μL Anmelden zum Anzeigen 13 bis 14 Tage
$393.25
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 18 Tage
$369.55
Details

Am meisten referenzierte anti-GDAP1 Antikörper

  1. Human Polyclonal GDAP1 Primary Antibody für ELISA, WB - ABIN565729 : Cassereau, Chevrollier, Gueguen, Malinge, Letournel, Nicolas, Richard, Ferre, Verny, Dubas, Procaccio, Amati-Bonneau, Bonneau, Reynier: Mitochondrial complex I deficiency in GDAP1-related autosomal dominant Charcot-Marie-Tooth disease (CMT2K). in Neurogenetics 2009 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen GDAP1 Interaktionspartner

Human Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) Interaktionspartner

  1. The mutation of GDAP1 gene may be related to the pathogenesis of autosomal dominant AD-CMT in this pedigree. The newly discovered c.371A>G mutation (p.Y124C) expands the mutation spectrum of GDAP1 gene, but further study is needed to clarify the underlying pathogenesis.

  2. This study showed that the characterization of GDAP1associated Charcot-Marie-Tooth disease.

  3. Study expands the mutational spectrum of GDAP1-related Charcot-Marie-Tooth (CMT) disease with the identification of new and unreported GDAP1 variants and demonstrates the predominance of the axonal form of neuropathy in CMT disease associated with GDAP1; highlights the clinical characteristics associated with these genotypes and describe the relative frequency of GDAP1 variants amongst the Chinese population.

  4. Study shows that GDAP1 is indeed a GST enzyme, and demonstrates a specific GSH-conjugating activity in vitro which seems to be regulated by the hydrophobic domain 1 (HD1) exerting an autoinhibitory function. HD1 could adopt an amphipathic pattern necessary to induce remodeling of organelles-mimicking liposomes by Gdap1.

  5. We identified GDAP1 variants in approximately 1% of our cohort with IPNs, and established a founder mutation in half of these patients. Our study originally described the mutational spectrum and clinical features of GDAP1-related CMT patients in Japan.

  6. This study report an AD-CMT2K with large phenotypic variability due to a novel dominant GDAP1 variant.

  7. GDAP1 hypomethylation can serve as a biomarker for alcohol dependence severity and treatment outcome.

  8. This study suggest GDAP1 as the first gene that should be analysed in Italian patients affected by CMT2.

  9. study reports on 2 Charcot-Marie-Tooth (CMT) families in which a newly identified Glu222Lys mutation within the GDAP1 gene segregates both in autosomal dominant and recessive traits

  10. The novelty of our data is the relatively high frequency of SH3TC2 and GDAP1 mutations in demyelinating and axonal forms, respectively, of Charcot-Marie-Tooth disease

  11. Results show that JPH1 and GDAP1 share a common pathway and depend on each other; therefore, JPH1 can contribute to the phenotypical consequences of GDAP1 mutations.

  12. GDAP1-associated polyneuropathy caused predominantly a mild and slowly progressive phenotype.

  13. This studies suggest that the pathophysiology of GDAP1-related CMT neuropathies may be associated with abnormal distribution and movement of mitochondria throughout cytoskeleton towards the ER and subplasmalemmal microdomains.

  14. GDAP1 regulates mitochondrial and peroxisomal fission by a similar mechanism.

  15. A novel heterozygous missense mutation (Arg120Gly) in the GDAP1 gene co-segregates with the disease within the pedigree of an Italian Charcot-Marie-Tooth disease type 2 (CMT2) family.

  16. This study suggested that the mutation of GDAP1 cased onion bulb-like formations of schwann cell in peripheral neuropathies.

  17. A French family with Charcot-Marie-Tooth disease is related to simultaneous heterozygous MFN2 and GDAP1 mutations.

  18. Patients of type 4 Charcot-Marie-Tooth disease showed reduced GDAP1 levels, GHS concentration and mitochondrial membrane potential.

  19. Charcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cells

  20. we report two recessive intermediate Charcot-Marie-Tooth (RI-CMT) patients with GDAP1 missense mutations

Mouse (Murine) Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) Interaktionspartner

  1. absence of GDAP1 induces a peripheral neuropathy with loss of motor neurons, mitochondrial defects and abnormal calcium homeostasis.

  2. Members of the GDAP1 family are responsive and protective against stress associated with increased levels of oxidized glutathione.

  3. Cell expression of Gdap1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease are reported.

GDAP1 Antigen-Profil

Protein Überblick

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.

Genbezeichner und Symbole assoziert mit GDAP1

  • ganglioside induced differentiation associated protein 1 (GDAP1) Antikörper
  • ganglioside-induced differentiation-associated-protein 1 (Gdap1) Antikörper
  • CMT4 Antikörper
  • CMT4A Antikörper
  • CMTRIA Antikörper

Bezeichner auf Proteinebene für GDAP1

ganglioside-induced differentiation-associated protein 1 , Charcot-Marie-Tooth neuropathy 4A , ganglioside differentiation associated protein 1

GENE ID SPEZIES
100172660 Pongo abelii
100050935 Equus caballus
54332 Homo sapiens
420191 Gallus gallus
487002 Canis lupus familiaris
100157012 Sus scrofa
613472 Bos taurus
14545 Mus musculus
312890 Rattus norvegicus
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