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Promotes the formation of filopodia.
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FGD3, which was identified as a homologue of FGD1 (zeige FGD1 Antikörper) but has been poorly characterized, has conserved the same motif and is down-regulated similarly by SCF (zeige KITLG Antikörper)(FWD1/beta-TrCP (zeige BTRC Antikörper)).
Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
FYVE, RhoGEF and PH domain containing 3
, FGD1 family, member 3
, FYVE, RhoGEF and PH domain-containing protein 3
, faciogenital dysplasia 3
, zinc finger FYVE domain-containing protein 5
, Fgd1 family, member 3
, faciogenital dysplasia homolog 3