F-Box and WD Repeat Domain Containing 4 Proteine (FBXW4)

FBXW4 is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. Zusätzlich bieten wir Ihnen FBXW4 Antikörper (80) und FBXW4 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FBXW4 6468 P57775
FBXW4 309444  
FBXW4 30838 Q9JMJ2
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Top FBXW4 Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$318.85
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FBXW4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Rat (Rattus)
Mouse (Murine) ,

Weitere Proteine zu F-Box and WD Repeat Domain Containing 4 (FBXW4) Interaktionspartnern

Human F-Box and WD Repeat Domain Containing 4 (FBXW4) Interaktionspartner

  1. biochemical characterization of the novel F-box and WD40 (zeige DCAF12L2 Proteine) containing protein, FBXW4

  2. a complex rearrangement associated with a approximately 0.5 Mb tandem duplication ion containing a disrupted extra copy of the DACTYLIN gene and the entire LBX1 (zeige Lbx1 Proteine) and beta-TRCP (zeige BTRC Proteine) genes.

  3. results indicate that genomic rearrangement of SHFM3 is rare among non-syndromic SHFM patients and emphasize the importance of screening for genomic rearrangements even in sporadic cases of SHFM

  4. Genomic rearrangements involving the SHFM3 locus at chromosome 10q24 is associated with syndromic and non-syndromic split-hand/foot malformation

Mouse (Murine) F-Box and WD Repeat Domain Containing 4 (FBXW4) Interaktionspartner

  1. Both dactylaplasia-related Dac (zeige DACH1 Proteine) insertions are caused by a type D mouse endogenous provirus (MusD) element, which can be silenced by Mda.

  2. Dactylaplasia in mouse is not associated with duplication of Fbxw4, in contrast with the described human cases.

FBXW4 Protein Überblick

Protein Überblick

This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds\; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.

Genbezeichner und Symbole assoziert mit FBXW4

  • F-box and WD repeat domain containing 4 (fbxw4)
  • F-box and WD repeat domain containing 4 (FBXW4)
  • F-box and WD repeat domain containing 4 (Fbxw4)
  • F-box and WD-40 domain protein 4 (Fbxw4)
  • Dac Protein
  • dactylin Protein
  • dactylyn Protein
  • Fbw4 Protein
  • FBWD4 Protein
  • FBXW4 Protein
  • hag Protein
  • hagoromo Protein
  • SHFM3 Protein
  • SHSF3 Protein
  • wu:fk63g06 Protein

Bezeichner auf Proteinebene für FBXW4

F-box/WD repeat-containing protein 4 , dactylaplasia , fk63g06 , F-box and WD repeat domain containing 4 , F-box and WD-40 domain protein 4 , F-box and WD-40 domain-containing protein 4 , F-box/WD repeat protein 4 , dactylin , F-box protein Fbw4 , protein hagoromo

GENE ID SPEZIES
58035 Danio rerio
450689 Pan troglodytes
6468 Homo sapiens
309444 Rattus norvegicus
100721914 Cavia porcellus
101113450 Ovis aries
30838 Mus musculus
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