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Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. Zusätzlich bieten wir Ihnen F-Box Protein 43 Kits (12) und F-Box Protein 43 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Rat (Rattus) Polyclonal FBXO43 Primary Antibody für ELISA, WB - ABIN335134
Perrard, Chassaing, Montillet, Sabido, Durand: Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes. in PLoS ONE 2009
Show all 2 Pubmed References
Cdc2 (zeige CDK1 Antikörper) and Mos (zeige MOS Antikörper) regulate Emi2 stability to promote the meiosis I-meiosis II transition
besides regulating cell-cycle arrest in mouse eggs, Emi2 is essential for meiosis I progression in spermatocytes. In the absence of Emi2, spermatocytes arrest in early diplotene of prophase I.
Data suggest that the increase of Wee 1 (zeige WEE1 Antikörper) tyrosine kinase (zeige TYRO3 Antikörper) but decrease of early mitotic inhibitor 2 level triggers maturation promoting factor (MPF (zeige MSLN Antikörper)) destabilization and thereby postovulatory aging-mediated abortive spontaneous egg activation in eggs.
These results suggest that in addition to the Mos (zeige MOS Antikörper)-MEK1 (zeige MAP2K1 Antikörper)/2 pathway, the Mos (zeige MOS Antikörper)-mediated p38 (zeige CRK Antikörper) pathway may be implicated in metaphase-II arrest.
data support the conclusion that zinc itself, through its interaction with EMI2, is a central component of the cytostatic factor
phosphorylation was required for up-regulation of the EMI2 activity in the oocytes. These results suggest that mouse MSK1 (zeige RPS6KA5 Antikörper) may play a key role in the metaphase-II arrest through phosphorylation of EMI2
separable N- and C-terminal domains of mouse Emi2 modulated metaphase establishment and maintenance, respectively, through indirect and direct mechanisms.
the APC (zeige APC Antikörper)/C-inhibitory activity of XErp1 (also known as Emi2) was essential for early divisions in Xenopus embryos.
Thus, Mos (zeige MOS Antikörper) and Erp1 collaboratively establish and maintain metaphase II arrest in Xenopus eggs
Emi2 stability and activity are dynamically regulated by Emi2-bound multiple kinases and PP2A (zeige PPP2R2B Antikörper) phosphatase.
Erp1/Emi2 is essential for the meiosis I to meiosis II transition in Xenopus oocytes.
Emi2 directs meiosis II-specific cytostatic factor cell cycle arrest.
Emi2/XErp1 is the critical cytostatic factor component directly responsible for anaphase-promoting complex/cyclosome inhibition during CSF (zeige CSF2 Antikörper) arrest.
These findings provide a novel mechanism of APC (zeige APC Antikörper)/C inhibition wherein the final step of ubiquitin transfer is targeted and raise the interesting possibility that APC (zeige APC Antikörper)/C is inhibited by Emi2 in a catalytic manner.
Data show that Emi2 binds the anaphase-promoting complex/cyclosome via the C-terminal tail.
review mechanism of action and mode of regulation of Emi2, CSF (zeige CSF2 Antikörper) function, and the general principles of APC (zeige APC Antikörper)/C regulation and control of protein function by MAPK (zeige MAPK1 Antikörper) pathways [review]
Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box only protein 43
, early mitotic inhibitor 2
, endogenous meiotic inhibitor 2
, XErp1 homolog
, F-box protein 43
, F-box only protein 43-like
, f-box only protein 43-like
, F-box protein 26
, emi1-related protein 1