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Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. Zusätzlich bieten wir Ihnen FBXO40 Antikörper (29) und FBXO40 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.
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In muscle from FBXO40 knockout pigs, IRS1 (zeige IRS1 Proteine) levels were higher, and the IGF1 (zeige IGF1 Proteine)/Akt (zeige AKT1 Proteine) pathway was stimulated. Mutant animals also had approximately 4% more muscle mass compared to WT controls.
The association analysis results indicated that the A/C base substitution in FBXO40 was associate with some hematological indexes.
FBXO40 may function as a regulator involved in the postnatal myogenesis.
The Fbxo40 is muscle specific (zeige EIF3K Proteine) in expression and is upregulated during differentiation.
Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box only protein 40
, F-box protein 40
, muscle and heart F-box protein 40
, muscle disease-related protein