anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) Antikörper

EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. Zusätzlich bieten wir Ihnen EWSR1 Proteine (4) und EWSR1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EWSR1 14030 Q61545
EWSR1 2130 Q01844
EWSR1 289752  
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Top anti-EWSR1 Antikörper auf antikoerper-online.de

Showing 10 out of 159 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EWSR1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate Lanes:   Lane 1: 50ug Hela Lysate  Primary Antibody Dilution:   1:1000  Secondary Antibody:   Anti-rabbit-HRP  Secondary Antibody Dilution:   1:10,000  Gene Name:   EWSR1  Submitted by:   Archa Fox, University of Western Australia  EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EWSR1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate. EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat Lanes:   Lane 1: 50ug Hela Lysate  Primary Antibody Dilution:   1:1000  Secondary Antibody:   Anti-rabbit-HRP  Secondary Antibody Dilution:   1:10,000  Gene Name:   EWSR1  Submitted by:   Archa Fox, University of Western Australia  EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EWSR1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells WB Suggested Anti-EWSR1 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: Jurkat cell lysate <br /> EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- EWSR1 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert IF, WB Western blot analysis of EWSR1 (arrow) using rabbit polyclonal EWSR1 Antibody (C-term) (ABIN658497). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EWSR1 gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Ziege Unkonjugiert IHC, ELISA, WB EB09167 (0.1µg/ml) staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of EWS expression in HepG2 (A), Jurkat (B), HeLa (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, PLA, WB Detection of Human EWS by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (50 and 100 mcg in A, 50 mcg for Input and one 10 cm plate for IP in B) from 293T cells. Antibodies: Affinity purified rabbit anti-EWS antibody ABIN152318 used at 0.2 and 0.1 mcg/ml for WB (A) and at 3 mcg/10 cm plate for IP (B). Immunoprecipitation was also performed with another normal rabbit IgG (Ctrl IgG), anti-EWS antibody and anti-EWS antibody ABIN152319. Detection: Chemiluminescence with exposure times of ~1 second (A) and 10 seconds (B). Western Blot: EWSR1 Antibody [ABIN152318] - Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-EWS antibody used for WB at 0.05 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$462.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Host: Rabbit Target Name: EWSR1 Sample Type: 721_B Whole cell lysates Antibody Dilution: 1.0ug/ml  EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit Anti-EWSR1 Antibody Catalog Number: ARP32266_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic, plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details

EWSR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Rat (Rattus)
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Am meisten referenzierte anti-EWSR1 Antikörper

  1. Human Polyclonal EWSR1 Primary Antibody für ICC, IF - ABIN152318 : Davis, Kim, Ozsolak, Widlund, Rozenblatt-Rosen, Granter, Du, Fletcher, Denny, Lessnick, Linehan, Kung, Fisher: Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. in Cancer cell 2006 (PubMed)

  2. Human Polyclonal EWSR1 Primary Antibody für IHC (p), IHC - ABIN449908 : Toretsky, Erkizan, Levenson, Abaan, Parvin, Cripe, Rice, Lee, Uren: Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A. in Cancer research 2006 (PubMed)

  3. Human Polyclonal EWSR1 Primary Antibody für IP, WB - ABIN152319 : Sohn, Park, Kang, Wu: Accumulation of pre-let-7g and downregulation of mature let-7g with the depletion of EWS. in Biochemical and biophysical research communications 2012 (PubMed)

Weitere Antikörper gegen EWSR1 Interaktionspartner

Mouse (Murine) Ewing Sarcoma Breakpoint Region 1 (EWSR1) Interaktionspartner

  1. Authors found that FUS (zeige FUS Antikörper), EWS and TAF15 (zeige TAF15 Antikörper) expression is differentially regulated during brain development, both in time and in space. In particular, this study identifies a fine-tuned regulation of FUS (zeige FUS Antikörper) and EWS during neuronal differentiation.

  2. Gnai1 (zeige GNAI1 Antikörper) function is impaired in the spinal cord of Ews/Ewsr1 KO mice

  3. EWS is normally O-GlcNAc glycosylated in the brain.

  4. glycosylation of EWS protein

  5. EWSR1 is involved in the post-transcriptional regulation of Uvrag (zeige UVRAG Antikörper) via a miRNA-dependent pathway, resulting in the deregulation of autophagy inhibition.

  6. EWS is essential during the early steps of white adipocyte differentiation, at least in part through its regulation of BMP2 (zeige BMP2 Antikörper) and BMP4 (zeige BMP4 Antikörper) expression.

  7. EWS has a role in mitochondrial and cellular energy homeostasis that involves controlling PGC-1alpha protein stability

  8. both Etv1 (zeige ETV1 Antikörper) and Ewsr1 were necessary for Fgf10 (zeige FGF10 Antikörper) expression and elongation of the limb bud.

  9. EWS is involved in post-transcriptional regulation of Col4a1 (zeige COL4A1 Antikörper) and CTGF (zeige CTGF Antikörper) via a Drosha (zeige DROSHA Antikörper)-miRNA-dependent pathway.

  10. These results demonstrate that EWS is essential for early brown fat lineage determination.

Zebrafish Ewing Sarcoma Breakpoint Region 1 (EWSR1) Interaktionspartner

  1. Mutation of the EWS gene modulates Sox9 (zeige SOX9 Antikörper) gene expression essential for chondrocyte differentiation.

  2. Ewsr1 maintains mitotic integrity and proneural cell survival in early zebrafish development

  3. Interaction between EWSR1/FLI1 (zeige FLI1 Antikörper) and EWSR1 in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Human Ewing Sarcoma Breakpoint Region 1 (EWSR1) Interaktionspartner

  1. ATG4B (zeige ATG4B Antikörper) expression was observed markedly upregulated by EWS-FLI1 (zeige FLI1 Antikörper) overexpression, and silencing of ATG4B (zeige ATG4B Antikörper) dramatically inhibits autophagy in Ewing sarcoma cells.

  2. Studies demonstrate that the translocation-derived fusion protein EF (EWS-FLI1 (zeige FLI1 Antikörper)) misregulates numerous genes involved in metabolism suggesting that EF is a master regulator of metabolic reprogramming in Ewing sarcoma, diverting metabolites toward biosynthesis.

  3. Together, the data demonstrate the critical requirement of GGAA-microsatellites as EWS/FLI (zeige FLII Antikörper) activating response elements in vivo and reveal an unexpected role for the EWS portion of the EWS/FLI (zeige FLII Antikörper) fusion in binding to sweet-spot GGAA-microsatellites.

  4. EWSR1 fusion protein is required for PAX7 (zeige PAX7 Antikörper) expression in Ewing sarcoma and identify a candidate EWSR1-FLI1 (zeige FLI1 Antikörper)-bound PAX7 (zeige PAX7 Antikörper) enhancer that coincides with both a consensus GGAA repeat-containing binding site and a peak of regulatory H3K27 acetylation.

  5. In the 3 cases of the primary extraskeletal myxoid chondrosarcoma (EMC) of bone we found the most frequent and specific chromosomal translocation t(9:22) EWSR1-NR4A3 (zeige NR4A3 Antikörper) of the extraskeletal counterpart.

  6. a breakpoint in the EWSR1-ATF1 (zeige AFT1 Antikörper) fusion to be the same as that reported in HCCC. Established CCOC-T cells grew extremely slowly, but the cells showed highly invasive activity

  7. study proposed that EWSR1 rearrangement was present in a subset of myoepithelial tumors of salivary glands, with variable morphological features

  8. EWSR1 Gene Rearrangement is associated with Endometrial Primitive Neuroectodermal Tumor.

  9. -cell lymphoblastic leukemia with t(11;22)(q24;q12) and EWSR1 rearrangement.

  10. Kinetics of EWSR1 fusion sequence copy numbers in the plasma are correlated with changes of the tumor volume in patients with localized and metastatic disease.

EWSR1 Antigen-Profil

Protein Überblick

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Genbezeichner und Symbole assoziert mit EWSR1

  • EWS RNA binding protein 1 (EWSR1) Antikörper
  • EWS RNA binding protein 1 (ewsr1) Antikörper
  • Ewing sarcoma breakpoint region 1 (Ewsr1) Antikörper
  • EWS RNA-binding protein 1a (ewsr1a) Antikörper
  • EWS RNA-binding protein 1 (Ewsr1) Antikörper
  • AU018891 Antikörper
  • bK984G1.4 Antikörper
  • DKFZp459K1116 Antikörper
  • Ews Antikörper
  • Ewsh Antikörper
  • EWSR1 Antikörper
  • fc04c01 Antikörper
  • wu:fc04c01 Antikörper

Bezeichner auf Proteinebene für EWSR1

RNA-binding protein EWS , Ewing sarcoma RNA-binding protein , Ewing sarcoma breakpoint region 1 , Ewing sarcoma homolog , Ewings sarcoma EWS-Fli1 (type 1) oncogene

GENE ID SPEZIES
748264 Pan troglodytes
100034010 Equus caballus
100018014 Monodelphis domestica
100173925 Pongo abelii
100550662 Meleagris gallopavo
100557388 Anolis carolinensis
100595788 Nomascus leucogenys
417022 Gallus gallus
609786 Canis lupus familiaris
534073 Bos taurus
14030 Mus musculus
100156911 Sus scrofa
323597 Danio rerio
2130 Homo sapiens
289752 Rattus norvegicus
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