anti-Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) Antikörper

EIF2B5 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Zusätzlich bieten wir Ihnen EIF2B5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EIF2B5 224045 Q8CHW4
EIF2B5 192234 Q64350
EIF2B5 8893 Q13144
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Top anti-EIF2B5 Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: eIF2B epsilon Antibody [NBP1-32783] - Sample (50 ug of whole cell lysate) A: mouse liver 7. 5% SDS PAGE; antibody diluted at 1:1000. Western Blot: eIF2B epsilon Antibody [NBP1-32783] - Sample (30 ug of whole cell lysate)A: H12997. 5% SDS PAGE, antibody diluted at 1:1000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Human Kaninchen Unkonjugiert IHC (p), IP, IHC Immunohistochemistry-Paraffin: eIF2B epsilon Antibody [NBP1-30449] - Human breast carcinoma. Antibody used at a dilution of 1:1,000. Immunoprecipitation: eIF2B epsilon Antibody [NBP1-30449] - Detection of Human eIF2B5 Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-eIF2B5 antibody NBP1-30449 used for IP at 10 mcg/mg lysate. eIF2B5 was also immunoprecipitated by rabbit anti-eIF2B5 antibody NBP1-30448, which recognizes an upstream epitope. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$559.35
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: eIF2B epsilon Antibody [NBP1-30448] - Human ovarian carcinoma. Antibody used at a dilution of 1:1,000. Western Blot: eIF2B epsilon Antibody [NBP1-30448] - Western Blot and Immunoprecipitation: Detection of Human eIF2B5 Whole cell lysate from HeLa and 293 cells. eIF2B5 was also immunoprecipitated by rabbit anti-eIF2B5 antibody NBP1-30449. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$559.35
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis in mouse testis tissue lysates (35ug/lane). EIF2B5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using EIF2B5 antibody. 200 μL Anmelden zum Anzeigen 12 bis 14 Tage
$438.90
Details
Human Maus Unkonjugiert ELISA, WB EIF2B5 polyclonal antibody (A01), Lot # 060814QCS1 Western Blot analysis of EIF2B5 expression in 293 . EIF2B5 polyclonal antibody (A01), Lot # 060113JC01. Western Blot analysis of EIF2B5 expression in human ovarian cancer. 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$793.83
Details
Human Kaninchen Unkonjugiert WB Western Blot showing EIF2B5 antibody used at a concentration of 1 ug/ml against U937 Cell Lysate 50 μg Anmelden zum Anzeigen 9 bis 11 Tage
$473.93
Details

Am meisten referenzierte anti-EIF2B5 Antikörper

  1. Cow (Bovine) Polyclonal EIF2B5 Primary Antibody für WB - ABIN2788769 : Wortham, Stewart, Harris, Coldwell, Proud: Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits. in The Biochemical journal 2016 (PubMed)

Weitere Antikörper gegen EIF2B5 Interaktionspartner

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) Interaktionspartner

  1. These results reveal a key role of the AKT-GSK3beta-eIF2Bepsilon signaling module in regulating axon regeneration in the adult mammalian central nervous system.

  2. analysis of eukaryotic initiation factor 2B epsilon phosphorylation sites and ubiquitin-modified lysine residues

  3. Data show that toll-like receptors (TLRs)-TRIF signalling activates eIF2B GEF through PP2A-mediated serine dephosphorylation of the eIF2B varepsilon-subunit.

  4. mouse model of EIF2B-related leukodystrophy; findings provide evidence that hypomorphic Eif2b5 alleles lead to delayed and abnormal development and maintenance of CNS white matter

  5. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha phosphorylation, reduction of eIF2B activity, and inhibition of eIF4F complex formation.

  6. inactivation of glycogen synthase kinase 3beta (GSK3beta) by high glucose and high insulin induces increase in synthesis of laminin beta1 via activation of eIF2Bepsilon.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) Interaktionspartner

  1. Exon-level analyses classified > 1,000 mRNAs as alternatively spliced under hypoxia and uncovered a unique retained intron (RI) in the master regulator of translation initiation, EIF2B5.

  2. This study demonstrated that no evidence for a role of Ile587Val polymorphism of EIF2B5 gene in multiple sclerosis in Kashmir Valley if India.

  3. Patient exhibits an early-infantile onset and progressive disease course resembling Cree leukoencephalopathy, suggesting a severe functional disruption of eIF2Bepsilon caused by R195H as well as by I408T mutations.

  4. Missense mutations in EIF2B5 are associated with multiple sclerosis.

  5. Also a mutation c.1913G>A[p.Arg638 His] in exon 14 of the EIF2B5-Gens as single nucleotide polymorphism.

  6. crystal structure of the guanine nucleotide exchange factor for elf2

  7. Functional analysis of recently identified mutations in eukaryotic translation initiation factor 2Bepsilon (eIF2Bepsilon) identified in Chinese patients with vanishing white matter disease

  8. The clinical phenotype in vanishing white matter disease is influenced by the combination of both mutations(p.Arg113His and p.Thr91Ala/p.Arg339any). Females tend to do better than males.

  9. Cree leukoencephalopathy and CACH/VWM disease are allelic at the EIF2B5 locus.

  10. Mutation in EIF2B5 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

  11. We demonstrated that mutations in the gene EIF2B5 cause "leukoencephalopathy with vanishing white matter." This gene encodes one of the five subunits of the translation factor eIF2B.

  12. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity.

  13. mutations in EIF2b5 causes a specific reduction in the generation of GFAP+ astrocytes in vanishing white matter disease

  14. Arg113His mutation in eIF2B5 associated with adult onset of vanishing white matter leukoencephalopathy is not present in multiple sclerosis patients

  15. We describe progressive megalencephaly and severe brain abnormalities due to specific EIF2Bepsilon mutations in two unrelated families.

  16. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon)

  17. These data support the importance of the non-catalytic domain of the eIF2Bepsilon subunit in the eIF2B complex formation and activity.

  18. no evidence for the involvement of EIF2B5 in multiple sclerosis susceptibility in France

  19. Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men.

EIF2B5 Antigen-Profil

Protein Überblick

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Genbezeichner und Symbole assoziert mit EIF2B5

  • eukaryotic translation initiation factor 2B subunit epsilon (EIF2B5) Antikörper
  • eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa (EIF2B5) Antikörper
  • Trimeric LpxA-like enzyme (AT2G34970) Antikörper
  • Trimeric LpxA-like enzyme (AT3G02270) Antikörper
  • translation initiation factor eif-2b epsilon subunit (AOR_1_624154) Antikörper
  • translation initiation factor eIF-2B epsilon subunit (CTRG_05484) Antikörper
  • translation initiation factor eIF-2B epsilon subunit (PAAG_05066) Antikörper
  • Translation initiation factor eIF-2B epsilon subunit, putative (CGB_A5380C) Antikörper
  • translation initiation factor eif-2b epsilon subunit (TERG_01115) Antikörper
  • eukaryotic translation initiation factor 2B, subunit 5 epsilon (Eif2b5) Antikörper
  • eukaryotic translation initiation factor 2B subunit epsilon (Eif2b5) Antikörper
  • AO090003000364 Antikörper
  • C81315 Antikörper
  • CACH Antikörper
  • CLE Antikörper
  • EIF-2B Antikörper
  • EIF2B5 Antikörper
  • EIF2Bepsilon Antikörper
  • F14P3.8 Antikörper
  • F14P3_8 Antikörper
  • F19I3.20 Antikörper
  • F19I3_20 Antikörper
  • LVWM Antikörper

Bezeichner auf Proteinebene für EIF2B5

eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa , translation initiation factor eIF-2B subunit epsilon , translation initiation factor eIF-2B subunit epsilon-like , translation initiation factor eIF-2B epsilon subunit , translation initiation factor eif-2b epsilon subunit , eIF-2B GDP-GTP exchange factor subunit epsilon , initiation factor eIF-2Be , eIF-2Bepsilon

GENE ID SPEZIES
424948 Gallus gallus
460881 Pan troglodytes
488103 Canis lupus familiaris
703673 Macaca mulatta
783760 Bos taurus
100389722 Callithrix jacchus
100446186 Pongo abelii
100580454 Nomascus leucogenys
818061 Arabidopsis thaliana
821200 Arabidopsis thaliana
5991536 Aspergillus oryzae RIB40
8300542 Candida tropicalis MYA-3404
9096172 Paracoccidioides sp. 'lutzii' Pb01
10187846 Cryptococcus gattii WM276
10373875 Trichophyton rubrum CBS 118892
224045 Mus musculus
192234 Rattus norvegicus
8893 Homo sapiens
100009393 Oryctolagus cuniculus
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