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EHF encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). Zusätzlich bieten wir Ihnen EHF Antikörper (26) und EHF Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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EHF is a novel functional oncogene (zeige RAB1A Proteine) in thyroid cancer by transcriptionally regulating HER2 (zeige ERBB2 Proteine) and HER3 (zeige ERBB3 Proteine), and may represent a potential therapeutic target for this cancer
The role of EHF in modifying Cystic Fibrosis (zeige S100A8 Proteine) lung disease severity.
is a novel functional oncogene (zeige RAB1A Proteine) in gastric cancer by regulating the human epidermal growth factor receptor (zeige EGFR Proteine) (HER) family of receptor tyrosine kinases.
tight control by ESE3/EHF over the Lin28 (zeige LIN28A Proteine)/let-7 axis is a critical barrier to malignant transformation.
ESE3 as a negative regulator of pancreatic ductal adenocarcinomas (PDAC) progression and metastasis by enforcing E-cadherin (zeige CDH1 Proteine) upregulation.
EHF activates expression of the SAM pointed domain-containing ETS transcription factor, which contributes to goblet cell hyperplasia.
Results found that EHF was elevated in ovarian cancer tissues and correlated with short survival. Its overexpression in ovarian cancer cells promoted cell growth and metastasis, and inhibited cell apoptosis.
This study suggests that ESE3 plays an important role in the carcinogenesis of Esophageal Squamous Cell Carcinoma through changes in subcellular localization and may act as a tumor suppressor gene in Esophageal Squamous Cell Carcinoma.
EHF modifies the CF phenotype by altering capabilities of the epithelial cell to correctly process the folding and trafficking of mutant p.Phe508del-CFTR (zeige CFTR Proteine).
Results suggest PPAR-gamma (zeige PPARG Proteine) to be involved in the regulation of ESE-3b expression during monocyte-derived dendritic cells (moDCs) development and that ESE-3 expression is not correlated with the immunogenicity of dendritic cells (DCs).
These data provide insights into the mechanisms underlying epithelial development and aging, identifying EHF as a regulator of cornea epithelial identity
This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene.
ETS homologous factor
, ESE3 transcription factor
, ETS domain-containing transcription factor
, epithelium-specific Ets transcription factor 3
, ets homologous factor