Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Proteine (EPB41)

The protein encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. Zusätzlich bieten wir Ihnen Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Antikörper (67) und Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
EPB41 2035 P11171
EPB41 269587 P48193
EPB41    
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Top Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Proteine auf antikoerper-online.de

Showing 7 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human EPB41 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$596.97
Details
Escherichia coli (E. coli) Maus Unkonjugiert SDS-PAGE analysis of Mouse EPB41 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$625.39
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,143.17
Details

EPB41 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine) ,
,
Chicken

Weitere Proteine zu Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartnern

Zebrafish Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartner

Human Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartner

  1. 6 Single Nucleotide Polymorphisms within the EPB41 gene are significantly associated with Mandibular Prognathism (rs2762686, rs2788888, rs4654388, rs502393, rs11581096, and rs488113). The G-allele of SNP, assigned as rs4654388, showed the strongest link with an increased risk of Mandibular Prognathism in the Chinese population.

  2. Our study shows alternative polyadenylation to be an additional mechanism for the generation of 4.1 protein diversity in the already complex EPB41-related genes. Understanding the diversity of EPB41 RNA processing is essential for a full appreciation of the many 4.1 proteins expressed in normal and pathological tissues.

  3. identification of EPB41 as a hepatocellular carcinoma susceptibility gene in vitro and in vivo; consistent with this notion, EPB41 expression is significantly decreased in HCC (zeige FAM126A Proteine) tissue specimens, especially in portal vein metastasis or intrahepatic metastasis, compared to normal tissues

  4. The 4.1R, 4.1N (zeige EPB41L1 Proteine) and 4.1B (zeige EPB41L3 Proteine) are all expressed at the lateral membrane as well as cytoplasm of epithelial cells, suggesting a potentially redundant role of these proteins.

  5. Calcium mediates the conformation-based 4.1R FERM domain binding to membrane proteins by calmodulin.

  6. Results suggest a previously unidentified role for the scaffolding protein 4.1R in locally controlling CLASP2 behavior, CLASP2 cortical platform turnover and GSK3 activity, enabling correct MT organization and dynamics essential for cell polarity.

  7. We conclude that PIP2 may play an important role as a modulator of apo (zeige C9orf3 Proteine)-CaM binding to 4.1R(80) throughout evolution.

  8. Plasmodium falciparum PF3D7_0402000 was identified as a new binding partner for the major erythrocyte cytoskeletal protein (zeige ACTN1 Proteine), 4.1R.

  9. a novel gene region, EPB41, which may be associated with smoking cessation, along with gene regions in CNR1 (zeige CNR1 Proteine) that may be targeted to further elucidate the etiology of gender differences in smoking behaviors.

  10. 4.1R regulates NHE1 (zeige SLC9A1 Proteine) activity through a direct protein-protein interaction that can be modulated by intracellular pH and Na(+) and Ca(2 (zeige CA2 Proteine)+) concentrations.

Xenopus laevis Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartner

  1. Data hypothesize that protein 4.1 (4.1R) could function as a linker protein (zeige LAT Proteine) between cytokeratin (zeige KRT1 Proteine) and the actin-based cytoskeleton.

Cow (Bovine) Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartner

  1. 4.1G interacts with a subset of CNG (zeige CNGA1 Proteine) channels and implicate this protein-protein interaction in organizing the spatial arrangement of CNG (zeige CNGA1 Proteine) channels in the plasma membrane of retinal outer segments.

  2. Band 4.1 protein is found in a retinal cDNA library screened for proteins interacting with the intracellular C-terminus of the metabotropic glutamate (zeige GRIN2A Proteine) receptor isoform 8a (mGluR8a).

Mouse (Murine) Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Interaktionspartner

  1. This suggests that 4.1R may influence myogenesis by preventing VHL (zeige VHL Proteine)-mediated myogenin (zeige MYOG Proteine) degradation.

  2. The proportion of 4.1R-positive cells was significantly higher in the HF group than in the controls, which was confirmed by the positive mRNA expression of 4.1R. 4.1R localized mostly to the plasma membrane of myocardial cells and was upregulated with the progression of HF. This suggests that 4.1R may be associated with HF progression.

  3. suggest that 4.1R can prevent pathogenic autoimmunity in MS/EAE progression by suppressing the CD4 (zeige CD4 Proteine)(+) T cell activation

  4. Loss of 4.1/NuMA interaction results in spindle orientation defects and inhibition of Cdk1 causes increase in cortical NuMA localization

  5. a functional role for 4.1R in small intestinal calcium absorption through regulation of membrane expression of PMCA1b (zeige ATP2B1 Proteine).

  6. At the intercalated disc 4.1R does not colocalise with the adherens junction protein, beta-catenin (zeige CTNNB1 Proteine), but does overlap with the other plasma membrane signalling proteins, the Na/K-ATPase (zeige ATP1A1 Proteine) and the Na/Ca exchanger NCX1 (zeige SLC8A1 Proteine).

  7. Cell adhesion and signaling pathways regulated by alphavbeta8 integrin and Band 4.1B (zeige EPB41L3 Proteine) are essential for normal formation and function of the heart during embryogenesis.

  8. A conserved exonic splicing silencer element (CE(16)) in protein 4.1R exon 16 (E16 (zeige SLC7A5 Proteine)) interacts with hnRNP A/B (zeige HNRNPAB Proteine) proteins & plays a role in repression of E16 (zeige SLC7A5 Proteine) splicing during early erythropoiesis

  9. We speculate that over the repetitive cycles of heart muscle contraction and relaxation, 4.1R is likely to locate, support, and coordinate functioning of key membrane-bound macromolecular assemblies.[Epb41]

  10. These results suggest that erythroid protein 4.1 plays a major role in volume regulation and physiologically downregulates Na/H exchange in mouse erythrocytes.

Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Protein Überblick

Protein Überblick

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit EPB41

  • erythrocyte membrane protein band 4.1b (epb41b)
  • erythrocyte membrane protein band 4.1 (EPB41)
  • erythrocyte membrane protein band 4.1 (epb41)
  • erythrocyte membrane protein band 4.1 L homeolog (epb41.L)
  • erythrocyte membrane protein band 4.1 (Epb41)
  • 4.1R Protein
  • AI415518 Protein
  • D4Ertd442e Protein
  • EL1 Protein
  • Elp-1 Protein
  • Elp1 Protein
  • Epb41 Protein
  • HE Protein
  • mKIAA4056 Protein
  • P4.1R Protein
  • wu:fb70c02 Protein

Bezeichner auf Proteinebene für EPB41

erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) , cha , mot , merlot , chablis , protein 4.1R , cytoskeletal protein 4.1 , protein 4.1 , protein 4.1-like , EPB4.1 , P4.1 , band 4.1 , erythrocyte surface protein band 4.1 , 4.1R , erythroid membrane skeletal protein 4.1 , erythroid protein 4.1

GENE ID SPEZIES
326287 Danio rerio
456689 Pan troglodytes
720360 Macaca mulatta
100038195 Xenopus (Silurana) tropicalis
100226658 Taeniopygia guttata
100350667 Oryctolagus cuniculus
100402250 Callithrix jacchus
100455211 Pongo abelii
100546883 Meleagris gallopavo
100563114 Anolis carolinensis
100596891 Nomascus leucogenys
2035 Homo sapiens
442955 Canis lupus familiaris
397741 Xenopus laevis
281753 Bos taurus
396493 Gallus gallus
100515614 Sus scrofa
269587 Mus musculus
Ausgewählte Anbieter für Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Proteine (EPB41)
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