Epstein-Barr Virus Induced 3 Proteine (EBI3)

EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Zusätzlich bieten wir Ihnen EBI3 Antikörper (143) und EBI3 Kits (21) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
EBI3 10148 Q14213
EBI3 50498 O35228
Ratte EBI3 EBI3 680609  
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Top EBI3 Proteine auf antikoerper-online.de

Showing 10 out of 38 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$736.00
Details
Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$638.00
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$638.00
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$230.67
Details
Escherichia coli (E. coli) Makake Unkonjugiert   50 μg Anmelden zum Anzeigen 1 bis 2 Tage
$165.73
Details
CHO Cells Human His tag   10 μg Anmelden zum Anzeigen 4 bis 8 Tage
$456.50
Details
Escherichia coli (E. coli) Epstein-Barr Virus Unkonjugiert SDS-PAGE analysis of Human EBI3 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$739.10
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$695.00
Details

EBI3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
,
Mouse (Murine) , ,
,

Am meisten referenzierte EBI3 Proteine

  1. Human EBI3 Protein expressed in CHO Cells - ABIN2719909 : Wang, Wei, Xiao, Liu, Zhang, Han, Chen, Hou, Ma, Shen, Li, Egwuagu, Wang: A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice. in European journal of immunology 2016 (PubMed)

  2. Human EBI3 Protein expressed in Wheat germ - ABIN3013374 : Guttek, Reinhold: Stimulated human peripheral T cells produce high amounts of IL-35 protein in a proliferation-dependent manner. in Cytokine 2013 (PubMed)

Weitere Proteine zu Epstein-Barr Virus Induced 3 (EBI3) Interaktionspartnern

Human Epstein-Barr Virus Induced 3 (EBI3) Interaktionspartner

  1. Researchers have constructed IL-35 gene-modified mesenchymal stem cells (MSCs)and explored their functions and mechanisms in some disease models. In this review, we discuss the potential tolerance-inducing effects of MSCs in transplantation and briefly introduce the immunoregulatory functions of the IL-35 gene-modified MSCs.

  2. IL-35 may be involved in the inflammatory process of sarcoidosis and play an important role in the pathogenesis of the disease.

  3. Tumor associated macrophages secrete interleukin-35 (IL-35) to facilitate metastatic colonization through activation of JAK2-STAT6-GATA3 signaling to reverse epithelial-mesenchymal transition (EMT) in cancer cells.

  4. Letter: circulating IL-35 is significantly higher than healthy controls and associate with disease activity in systemic lupus erythematosus.

  5. A decrease in the IL-35 (IL-12A+EBI3) serum levels may play an important role in the pathogenesis of primary Sjogren's syndrome.

  6. IL-35 is induced during atherosclerosis development and inhibits mitochondrial reactive oxygen species-H3K14 acetylation-AP-1-mediated endothelial activation.

  7. The IL-35 levels in CagA(+) H. pylori-infected participants from peptic ulcer and H. pylori-infected asymptomatic groups were lower than individuals infected with CagA(-) strains.

  8. IL-35 may be involved in the pathogenesis of Primary biliary cirrhosis.

  9. IL-35 is a relatively newly discovered member of the IL-12 family which are unique in structure as they are dimer formed by two subunits; recent findings have shown abnormal expression of IL-35 in inflammatory autoimmune diseases and functional analysis suggested that IL-35 is critical in the onset and development of these diseases. [Review]

  10. IL-35 expression was significantly increased in patients with chronic hepatitis C and was positively correlated with the levels of viral RNA

  11. Pancreatic ductal carcinoma cells produce IL35 to recruit monocytes via CCL5 and induce macrophage to promote angiogenesis via expression of CXCL1 and CXCL8.

  12. The study revealed that post-therapeutic recovery of circulating IL-35 concentration might be an independent predictor for effective response to IST in pediatric AA.

  13. The plasma levels of interleukin-35 were significantly higher in the hepatocellular carcinoma patients than the controls.

  14. this study introduces IL-35 as a new treatment for pemphigus

  15. over-expression of EBI3 could reduce the apoptosis of Treg/CD4(+)T/CD8(+)T cells and prevent radiation-induced immunosuppression of cervical cancer HeLa cells by inhibiting the activation of PD-1/PD-L1 signaling pathway

  16. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) levels were significantly elevated in the patients with influenza infection.

  17. higher decidual mRNA expression in preeclampsia

  18. IL-35 was elevated in bone marrow of adult AML patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML.

  19. Elevated circulating IL-35, particularly at early phase, its decrease after treatment initiation, and a positive association between synovial fluid IL-35 and disease activity support an involvement of IL-35 in the pathogenesis of RA.

  20. Data suggest that the toll like receptor 3 (TLR3)-interferon regulatory factor 6 protein (IRF6)-interleukin-23 subunit p19 (p19)/EBI3 protein axis may regulate keratinocyte functions in the skin.

Mouse (Murine) Epstein-Barr Virus Induced 3 (EBI3) Interaktionspartner

  1. Interleukin-35 inhibited non-small cell lung cancer formation in the mice model and sensitized the cancer cells to chemotherapy drugs.

  2. Tumor associated macrophages secrete interleukin-35 (IL-35) to facilitate metastatic colonization through activation of JAK2-STAT6-GATA3 signaling to reverse epithelial-mesenchymal transition (EMT) in cancer cells.

  3. IL-35 is induced during atherosclerosis development and inhibits mitochondrial reactive oxygen species-H3K14 acetylation-AP-1-mediated endothelial activation.

  4. Data indicate an increase in the intracellular Epstein-Barr virus-induced 3 (EBI3) protein level in splenic NK cells during mouse cytomegalovirus (MCMV) infection.

  5. IL-35-transduced adipocyte-derived mesenchymal stem cells in vivo can enhance proliferation of CD4(+) CD25(+) Treg cells and suppress the function of effector T cells such as T helper (Th) 1, Th2 and Th17 cells and may reduce the development of allograft rejection.

  6. we describe here a new IL-12 member IL-39 (IL-23p19/Ebi3) secreted by activated B cells that mediate inflammatory responses in lupus-like mice. Thus, IL-39 might contribute to immunopathogenic mechanisms of SLE.

  7. EBI3 can mediate IL-6 trans-signaling in a process that involves gp130

  8. our results suggest that IL-39 induces differentiation and/or expansion of neutrophils in lupus-prone mice.

  9. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.

  10. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  11. Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.

  12. our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease

  13. Report higher EBI3 expression in the lung tissue of BCG-infected mice.

  14. EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.

  15. IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.

  16. Lack of EBI3, p35, and IL-12 receptor beta2 caused enhanced infiltration of lymphocytes into the testicular interstitium, with increased interferon-gamma expression in the testes and autoantibody production against mainly acrosomal regions of spermatids.

  17. Data (including data from knockout mice) suggest Ebi3 (Epstein-Barr virus induced protein 3) and IL12 (interleukin 12) down-regulate helper-inducer T-lymphocyte (Th17 cell) function in immune response to Listeria monocytogenes.

  18. results indicate that EBI3 may be important in EAU initiation by Th1 cell responses and may suppress experimental autoimmune uveitis by inhibition of both Th1 and Th17 cell responses in the late/maintenance phase.

  19. Anti-CD200R2, anti-IL-9, anti-IL-35, or anti-TGF-beta abolishes increased graft survival and Treg induction induced in cromolyn-treated CD200R1KO.CD200tg mice, and suggest combined role of mast cells and Tregs.

  20. the findings from the past decade identify IL-27 as a critical immunoregulatory cytokine, especially for T cells, whereas some controversy is fueled by results challenging the view of IL-27 as a classical silencer of inflammation.

EBI3 Protein Überblick

Protein Überblick

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Genbezeichner und Symbole assoziert mit EBI3

  • Epstein-Barr virus induced 3 (EBI3)
  • Epstein-Barr virus induced 3 (ebi3)
  • Epstein-Barr virus induced gene 3 (Ebi3)
  • Epstein-Barr virus induced 3 (Ebi3)
  • EBI-3 Protein
  • EBI3 Protein
  • IL-27 Protein
  • IL-27B Protein
  • il-27rb Protein
  • IL27B Protein
  • si:dkey-97a13.4 Protein

Bezeichner auf Proteinebene für EBI3

EBV-induced gene 3 protein , Epstein-Barr virus induced gene 3 , IL-27 subunit beta , IL27 subunit , IL35 subunit , cytokine receptor , epstein-Barr virus-induced gene 3 protein , interleukin-27 subunit beta , Epstein-Barr virus induced 3 , Il27rbeta , interleukin 27 receptor beta , IL-27B , epstein-Barr virus-induced gene 3 protein homolog , Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor)

GENE ID SPEZIES
10148 Homo sapiens
485043 Canis lupus familiaris
514933 Bos taurus
737135 Pan troglodytes
100134974 Danio rerio
50498 Mus musculus
680609 Rattus norvegicus
Ausgewählte Anbieter für EBI3 Proteine (EBI3)
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