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ENO3 encodes one of the three enolase isoenzymes found in mammals.
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This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.
, enolase 3 (beta, muscle)
, 2-phospho-D-glycerate hydro-lyase
, phosphopyruvate hydratase
, 2-phospho-D-glycerate hydrolyase
, muscle-specific enolase
, skeletal muscle enolase
, beta beta enolase
, enolase 1, (alpha)
, beta-enolase 3
, Muscle specific enolase (beta beta enolose) (two splicing products)