Enhancer of MRNA Decapping 4 Proteine (EDC4)

In the process of mRNA degradation, seems to play a role in mRNA decapping (By similarity). Zusätzlich bieten wir Ihnen EDC4 Antikörper (33) und EDC4 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
EDC4 23644 Q6P2E9
EDC4 234699 Q3UJB9
Ratte EDC4 EDC4 361399 Q3ZAV8
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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EDC4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Enhancer of MRNA Decapping 4 (EDC4) Interaktionspartnern

Arabidopsis thaliana Enhancer of MRNA Decapping 4 (EDC4) Interaktionspartner

  1. Data suggest that specific motifs, secondary energy, and GC content of transcripts could play a role in their degradation by exoribonuclease4 (xrn4) and varicose (vcs).

  2. Seedling lethal phenotypes in dcp1 (zeige ACE Proteine), dcp2 (zeige DCP2 Proteine) and vcs mutants are caused the disruption of miRNA-mediated gene regulation.

  3. DCP2 (zeige DCP2 Proteine) interacts in vitro and in vivo with DCP1 (zeige ACE Proteine) and VARICOSE (VCS), an Arabidopsis homolog of human Hedls/Ge-1, suggesting that the three proteins operate as a decapping complex.

Human Enhancer of MRNA Decapping 4 (EDC4) Interaktionspartner

  1. EDC4 plays a key role in homologous recombination by stimulating end resection at double-strand breaks.

  2. The assembly of EDC4 and Dcp1a (zeige DCP1A Proteine) into processing bodies is critical for the translational regulation of IL-6 (zeige IL6 Proteine).

  3. LMKB is the first protein identified to date that interacts with this portion of Ge-1. LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L (zeige IFI44L Proteine).

  4. EDC4 is a processing body (P-body) component.

  5. The data indicates that DCP2 (zeige DCP2 Proteine) activation by DCP1 (zeige ACE Proteine) occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 (zeige DCP2 Proteine) activation by DCP1 (zeige ACE Proteine) with 5'-to-3' mRNA degradation by XRN1 (zeige XRN1 Proteine) in human cells.

  6. EDC4 might contribute to regulation of CoA biosynthesis in addition to its scaffold function in processing bodies

Mouse (Murine) Enhancer of MRNA Decapping 4 (EDC4) Interaktionspartner

  1. Ge-1, the human ortholog of mouse Edc4, was shown to localize to mRNA processing bodies (P-body)in a human cell line. The C-terminal region is required for this localization.

  2. The human Ge-1 gene (also known as Hedls and Edc4)is an ortholog of mouse Edc4. The gene was identified by screening a cDNA expression library using serum from a patient with Sjogren's syndrome.

EDC4 Protein Überblick

Protein Überblick

In the process of mRNA degradation, seems to play a role in mRNA decapping (By similarity).

Genbezeichner und Symbole assoziert mit EDC4

  • enhancer of mRNA decapping 4 (EDC4)
  • Transducin/WD40 repeat-like superfamily protein (VCS)
  • enhancer of mRNA decapping 4 (edc4)
  • enhancer of mRNA decapping 4 (Edc4)
  • enhancer of mRNA decapping 4 L homeolog (edc4.L)
  • BC022641 Protein
  • Ge-1 Protein
  • GE1 Protein
  • HEDL5 Protein
  • HEDLS Protein
  • LRRG00115 Protein
  • Nrn1l Protein
  • RCD-8 Protein
  • RCD8 Protein
  • RGD1309136 Protein
  • si:ch211-237c7.1 Protein
  • VARICOSE Protein
  • wu:fe26b05 Protein

Bezeichner auf Proteinebene für EDC4

enhancer of mRNA decapping 4 , autoantigen Ge-1 , autoantigen RCD-8 , enhancer of mRNA-decapping protein 4 , human enhancer of decapping large subunit , autoantigen RCD8 , fe26b05

GENE ID SPEZIES
415656 Gallus gallus
454178 Pan troglodytes
820530 Arabidopsis thaliana
100379843 Xenopus (Silurana) tropicalis
23644 Homo sapiens
234699 Mus musculus
565659 Danio rerio
379239 Xenopus laevis
489751 Canis lupus familiaris
513171 Bos taurus
361399 Rattus norvegicus
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