Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) Proteine (EDC3)

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]..

alle Proteine anzeigen Gen GeneID UniProt
Ratte EDC3 EDC3 315708  
Human EDC3 EDC3 80153 Q96F86
Maus EDC3 EDC3 353190 Q8K2D3
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Schizosaccharomyces pombe His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,274.33
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Weitere Proteine zu Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) Interaktionspartner

  1. The modular architecture enables enhancer of decapping 3 (EDC3) to interact with multiple components of the decapping (zeige ACE Proteine) machi (zeige DCP2 Proteine)nery, inclu (zeige DDX6 Proteine)ding DCP1, DCP2, and Me31B.

  2. Tral (zeige LSM14A Proteine) and EDC3 specifically interact with the decapping activator DCP1 (zeige ACE Proteine) and the DEAD-box helicase Me31B (zeige DDX6 Proteine), in Drosophila cells.

Human Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) Interaktionspartner

  1. In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 (zeige DCP2 Proteine) decapping at low concentrations and even inhibits DCP2 (zeige DCP2 Proteine) decapping at high concentration.

  2. The modular architecture enables EDC3 to interact with multiple components of the decapping machinery, including DCP1 (zeige ACE Proteine), DCP2 (zeige DCP2 Proteine), and Me31B (zeige DDX6 Proteine).

  3. The dimerization interface of Edc3 is highly conserved in eukaryotes despite the overall low sequence homology across species; structure-based site-directed mutagenesis revealed dimerization is required for efficient RNA binding, P-body formation

  4. Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral (zeige LSM14A Proteine) to the DEAD box protein (zeige INTS6 Proteine) DDX6/Me31B (zeige DDX6 Proteine).

Mouse (Murine) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) Interaktionspartner

  1. Induction of 14-3-3 (zeige YWHAQ Proteine) binding to EDC3 causes morphological changes in processing body structures, inhibition of microRNA-mediated mRNA post-transcriptional regulation, and alterations in the protein- protein interactions of EDC3.

EDC3 Protein Überblick

Protein Überblick

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005

Genbezeichner und Symbole assoziert mit EDC3

  • enhancer of mRNA decapping 3 (Edc3)
  • Enhancer of decapping 3 (Edc3)
  • enhancer of mRNA decapping 3 S homeolog (edc3.S)
  • enhancer of mRNA decapping 3 (EDC3)
  • enhancer of mRNA decapping 3 homolog (S. cerevisiae) (edc3)
  • AA517853 Protein
  • CG6311 Protein
  • DmEDC3 Protein
  • Dmel\\CG6311 Protein
  • EDC3 Protein
  • im:7151288 Protein
  • lsm16 Protein
  • RGD1306898 Protein
  • wu:fb82d07 Protein
  • Yjdc Protein
  • YJEFN2 Protein
  • zgc:112006 Protein

Bezeichner auf Proteinebene für EDC3

LSM16 homolog (EDC3, S. cerevisiae) , CG6311-PB , Edc3-PB , enhancer of decapping 3 , enhancer of decapping-3 , enhancer of mRNA decapping 3 homolog , enhancer of mRNA-decapping protein 3 , yjeF domain-containing protein 1 , hYjeF_N2 , hYjeF_N2-15q23 , yjeF N-terminal domain-containing protein 2 , yjeF domain containing , yjeF_N2 , LSM16 protein homolog

GENE ID SPEZIES
315708 Rattus norvegicus
39957 Drosophila melanogaster
495065 Xenopus laevis
100171859 Pongo abelii
80153 Homo sapiens
353190 Mus musculus
415294 Gallus gallus
504054 Danio rerio
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