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The protein encoded by ELAC2 has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. Zusätzlich bieten wir Ihnen ElaC Homolog 2 (E. Coli) Antikörper (45) und viele weitere Produktgruppen zu diesem Protein an.
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The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
RNase Z 2
, elaC homolog protein 2
, ribonuclease Z 2
, tRNA 3 endonuclease 2
, tRNase Z 2
, tRNase Z(L)
, zinc phosphodiesterase ELAC protein 2
, elaC homolog 2
, heredity prostate cancer protein 2
, putative prostate cancer susceptibility protein HPC2/ELAC2
, tRNase Z (long form)