ElaC Homolog 2 (E. Coli) Proteine (ELAC2)

The protein encoded by ELAC2 has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. Zusätzlich bieten wir Ihnen ElaC Homolog 2 (E. Coli) Antikörper (54) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ELAC2 68626 Q80Y81
ELAC2 60528 Q9BQ52
Ratte ELAC2 ELAC2 282826 Q8CGS5
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Top ElaC Homolog 2 (E. Coli) Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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ELAC2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu ElaC Homolog 2 (E. Coli) (ELAC2) Interaktionspartnern

Human ElaC Homolog 2 (E. Coli) (ELAC2) Interaktionspartner

  1. This study describes the cardiac phenotype and outcome of ELAC2 mutation in Infantile Cardiomyopathy

  2. ELAC2 rs11545302 polymorphism was associated with PSA > 20 and rs4792311 was associated with TNM > 2.

  3. A homozygous splicing mutation in ELAC2 suggests phenotypic variability including intellectual disability with minimal cardiac involvement

  4. ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy.

  5. results indicate that ELAC2 functions as a tRNase Z in human mitochondria and suggest that mt-tRNase Z preferentially cleaves molecules already processed by the proteinaceous mtRNase P

  6. ELAC2 and PTCD1 affect the 3' end processing of tRNAs.

  7. analysis of dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation

  8. Data describe polymorphisms in the HPC/ELAC-2 and alpha 1-antitrypsin (zeige SERPINA1 Proteine) genes that correlate with human diseases in an Indian population.

  9. ELAC2 polymorphisms are associated with prostate cancer.

  10. Our findings corroborate the involvement of ELAC2, MSR1 (zeige MSR1 Proteine), and RNASEL (zeige RNASEL Proteine) in the etiology of prostate cancer even in individuals without a family history.

ElaC Homolog 2 (E. Coli) (ELAC2) Protein Überblick

Protein Überblick

The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit ELAC2

  • elaC ribonuclease Z 2 (ELAC2)
  • elaC ribonuclease Z 2 (Elac2)
  • 1110017O07Rik Protein
  • D11Wsu80e Protein
  • ELC2 Protein
  • HPC2 Protein

Bezeichner auf Proteinebene für ELAC2

RNase Z 2 , elaC homolog protein 2 , ribonuclease Z 2 , tRNA 3 endonuclease 2 , tRNase Z 2 , tRNase Z(L) , zinc phosphodiesterase ELAC protein 2 , elaC homolog 2 , heredity prostate cancer protein 2 , putative prostate cancer susceptibility protein HPC2/ELAC2 , tRNase Z (long form)

GENE ID SPEZIES
489511 Canis lupus familiaris
68626 Mus musculus
450109 Pan troglodytes
60528 Homo sapiens
282826 Rattus norvegicus
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