anti-Early Growth Response 2 (EGR2) Antikörper

The protein encoded by EGR2 is a transcription factor with three tandem C2H2-type zinc fingers.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human EGR2 EGR2 1959 P11161
Anti-Maus EGR2 EGR2 13654 P08152
Anti-Ratte EGR2 EGR2 114090 P51774
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Top anti-EGR2 Antikörper auf antikoerper-online.de

Showing 10 out of 124 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EGR2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung Human Intestine 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN334389 (0.03µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Kaninchen Unkonjugiert IHC (fro), WB WB Image Western Blot analysis of EGR2 expression in transfected 293T cell line by EGR2 polyclonal antibody. A: Non-transfected lysate. B: EGR2 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 IHC-Fr Image Immunohistochemical analysis of mouse brain tissue (paraformaldehyde-fixed frozen sections), using EGR2, antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Detection of EGR2 in human fetal lung tissue using ABIN258617. Immunocytochemistry/Immunofluorescence: EGR2 Antibody [ABIN2586173] - EGR2 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Anmelden zum Anzeigen 34 Days
$415.44
Details
Human Maus Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Hund Ziege Unkonjugiert EIA, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Kaninchen Unkonjugiert WB Anti-EGR2 antibody, Western blotting Lane 1: NIH3T3 Cell Lysate Lane 2: MCF-7 Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details

Am meisten referenzierte anti-EGR2 Antikörper

  1. Cow (Bovine) Polyclonal EGR2 Primary Antibody für IHC, WB - ABIN2792631 : Yoo, Lee: Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal EGR2 Primary Antibody für IHC (p), IHC - ABIN261100 : LeBlanc, Ward, Svaren: Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. in Molecular and cellular biology 2007 (PubMed)

  3. Polyclonal EGR2 Primary Antibody für WB - ABIN540733 : Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal EGR2 Primary Antibody für ICC, IF - ABIN258617 : Hinze, Mayer, Harst, von Kügelgen: Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes. in Journal of molecular and cellular cardiology 2012 (PubMed)

Weitere Antikörper gegen EGR2 Interaktionspartner

Human Early Growth Response 2 (EGR2) Interaktionspartner

  1. Low EGR2 expression is associated with hepatocellular carcinoma.

  2. The study suggests that acetylation of EGR2 is regulated independently of nucleosome remodeling and deacetylase.

  3. Egr2-driven cell surface proteins LAG-3 (zeige LAG3 Antikörper) and 4-1BB (zeige TNFRSF9 Antikörper) can identify dysfunctional tumor antigen-specific CD8 (zeige CD8A Antikörper)(+) TIL (zeige TLR1 Antikörper).

  4. Egr2 and Egr3 (zeige EGR3 Antikörper) have emerged as regulatory molecules that suppress excessive immune responses. Mice deficient for Egr2 and Egr3 (zeige EGR3 Antikörper) develop a lupus-like disease with dysregulated activation of effector T cells. Egr2 and Egr3 (zeige EGR3 Antikörper) confer suppressive activity to CD4 (zeige CD4 Antikörper)(+) T cells and regulate the production of inhibitory cytokines such as IL-10 (zeige IL10 Antikörper) and TGF-beta1 (zeige TGFB1 Antikörper).

  5. Analysis of consensus EGR (zeige EGR1 Antikörper)-binding elements (EBEs) showed that the immediate early response 3 (zeige IER3 Antikörper) gene (IER3 (zeige IER3 Antikörper)) is a novel transcriptional target gene of EGR2 as confirmed by the luciferase assay, electrophoretic mobility-shift assay (EMSA), chromatin immunoprecipitation (ChIP), and western blot analysis.

  6. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2 (zeige NR4A2 Antikörper))early growth response (EGR)2 and NR4A2EGR3. Therefore, RUNX1 (zeige RUNX1 Antikörper), NR4A2 (zeige NR4A2 Antikörper), EGR2, EGR3 (zeige EGR3 Antikörper) and ID4 (zeige ID4 Antikörper) may be key genes associated with the pathogenesis of DS.

  7. EGR2 mutation presents as an axonal Charcot-Marie-Tooth phenotype with variable severity.

  8. MicroRNA20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing EGR2 expression.

  9. These results suggested that EGR2 overexpression has a pivotal role in the downregulation of cytokines implicated in the pathophysiology of Guillain-Barre syndrome

  10. A recurrent mutation was identified in EGR2 which appears to be associated with the pathogenesis of schizophrenia.

Mouse (Murine) Early Growth Response 2 (EGR2) Interaktionspartner

  1. Egr2 and Egr3 (zeige EGR3 Antikörper) expressed in T cells cooperatively prevent humoral immune responses by supporting TGF-beta3 (zeige TGFB3 Antikörper) secretion.

  2. study revealed GCN5 (zeige KAT2A Antikörper)-mediated EGR2 acetylation as a molecular mechanism that regulates iNKT development.

  3. findings demonstrate a crucial role for Krox20 in arterial valve development and reveal that an excess of neural crest cells may be associated with bicuspid aortic valve.

  4. these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 and YY1 (zeige YY1 Antikörper) in NIH3T3 cells

  5. Prss56 (zeige PRSS56 Antikörper) expression was regulated by Egr2 during mouse decidualization.

  6. Egr2 and 3 are upstream regulators of effector CD4 (zeige CD4 Antikörper) and CD8 (zeige CD8A Antikörper) T cells that are essential for optimal responses with limited immunopathology.

  7. Egr2 and 3 are antagonists of T-bet function in effector T cells and are important for the control of inflammatory responses of T cells.

  8. We discovered that Tead1 (zeige TEAD1 Antikörper) and co-activators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) are required for Pmp22 (zeige PMP22 Antikörper) expression, as well as for the expression of Egr2 Tead1 (zeige TEAD1 Antikörper) directly binds Pmp22 (zeige PMP22 Antikörper) and Egr2 enhancers early in development and Tead1 (zeige TEAD1 Antikörper) binding is induced during myelination, correlating with Pmp22 (zeige PMP22 Antikörper) expression. The data identify Tead1 (zeige TEAD1 Antikörper) as a novel regulator of Pmp22 (zeige PMP22 Antikörper) expression during development in concert with Sox10 (zeige SOX10 Antikörper) and Egr2

  9. endogenous KLF4 (zeige KLF4 Antikörper) and Krox20 are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma (zeige PPARG Antikörper)) is essential.

  10. Decreased expression of Krox20 in mice causes degeneration of the aortic leaflets and disorganization of the extracellular matrix, causing valvular dysfunction.

Zebrafish Early Growth Response 2 (EGR2) Interaktionspartner

  1. A direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing vertebrate hindbrain segmentation.

  2. Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4.

  3. Data show that Irx7 and Irx1b are required for the proper formation and specification of rhombomeres 1 to 4, and that Irx7 functionally interacts with Meis1.1 (zeige MEIS1 Antikörper) to activate the expression of anterior hindbrain markers, such as krox20.

EGR2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit EGR2

  • early growth response 2 (EGR2) Antikörper
  • early growth response 2 (Egr2) Antikörper
  • early growth response 2b (egr2b) Antikörper
  • AT591 Antikörper
  • cb427 Antikörper
  • CMT1D Antikörper
  • CMT4E Antikörper
  • Egr-2 Antikörper
  • egr2 Antikörper
  • id:ibd5073 Antikörper
  • Krox-20 Antikörper
  • krox20 Antikörper
  • KRX-20 Antikörper
  • krx20 Antikörper
  • NGF1-B Antikörper
  • wu:fb71h10 Antikörper
  • Zfp-6 Antikörper
  • Zfp-25 Antikörper
  • zgc:92210 Antikörper

Bezeichner auf Proteinebene für EGR2

E3 SUMO-protein ligase EGR2 , KROX-20, Drosophila, homolog (early growth response-2) , early growth response protein 2 , zinc finger protein Krox-20 , early growth response 2 (Krox-20 homolog, Drosophila) , EGR-2 , EGR-2b , early growth response protein 2b , krox-20 , protein krx-20

GENE ID SPEZIES
1959 Homo sapiens
479219 Canis lupus familiaris
100038004 Sus scrofa
13654 Mus musculus
114090 Rattus norvegicus
100721167 Cavia porcellus
100297981 Bos taurus
101122407 Ovis aries
30190 Danio rerio
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