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The protein encoded by EBF2 belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. Zusätzlich bieten wir Ihnen Early B-Cell Factor 2 Antikörper (32) und viele weitere Produktgruppen zu diesem Protein an.
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Data suggest that Her5 acts as a prepattern gene to suppress both neurogenin1 (ngn1 (zeige NEUROG1 Proteine)) and coe2 mRNA expression and to prevent neurogenesis in the anlage of the midbrain/hindbrain boundary in the zebrafish neural plate.
we show that SIX1 (zeige SIX1 Proteine) binds to adipogenic and brown marker genes and interacts with C/EBPa (zeige CEBPA Proteine), C/EBPb (zeige CEBPB Proteine) and EBF2, suggesting their functional cooperation during adipogenesis.
Data indicate that Contactin-1 (zeige CNTN1 Proteine) expression is dependent upon EBF (zeige EBF1 Proteine) factors; Cntn1 (zeige CNTN1 Proteine) gene belongs to the expanding regulatory cascade driven by these transcriptional regulators so that changes in its activation may contribute to the Ebf2 null mutant phenotype
Study identified Ebf2 as a novel and important regulator selectively required for midbrain periaqueductal gray matter dopamine neuron development
Results indicate that early B cell factor 2 (Ebf2) specifically marks and regulates the molecular profile of brown preadipose cells.
Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype.
Ebf2 protein recruits Pparg (zeige PPARG Proteine) to brown fat-selective gene targets, including Prdm16 (zeige PRDM16 Proteine), to determine brown identity.
These findings indicate that Ebf2 is important for the development and maintenance of normal Purkinje cell discharge properties
Ebf2 and Ebf3 (zeige EBF3 Proteine), singly or together, control the migration of Cajal-Retzius cells arising in the cortical hem. These findings provide evidence that Ebfs directly regulate Cajal-Retzius cell development
Ebf2 is important for early cortical neurogenesis and regulates the generation of Cajal-Retzius neurons in the developing cerebral cortex.
Ebf2 is implicated in peripheral nerve development as a potential candidate gene for peripheral nerve disorders.
EBF (zeige EBF1 Proteine) activity is important for both stabilizing commitment and driving aspects of differentiation in Xenopus muscle cells.
Novel inguinal hernia susceptibility genes are identified as EFEMP1 (zeige FBLN3 Proteine), WT1 (zeige WT1 Proteine), EBF2 and ADAMTS6 (zeige ADAMTS6 Proteine).
EBF2 as a mediator of osteoprotegerin (zeige TNFRSF11B Proteine) inhibition to tumor necrosis factor (zeige TNF Proteine)-related apoptosis-inducing ligand-induced apoptosis.
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. The COE family proteins play an important role in variety of developmental processes. Studies in mouse suggest that this gene may be involved in the differentiation of osteoblasts.
early B-cell factor 2
, HLH-containing transcription factor
, transcription factor COE2
, MET-mesencephalon-olfactory TF1
, MET-mesencephalon-olfactory transcription factor 1
, Olf-1/EBF-like 3
, metencephalon-mesencephalon-olfactory transcription factor 1
, Early B-cell factor 2-A
, transcription factor coe2-A
, Collier, Olf and EBF 2
, OLF-1/EBF-LIKE 3
, metencephalon-mesencephalnon-olfactory transcription factor 1