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Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.. Zusätzlich bieten wir Ihnen EBF1 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal EBF1 Primary Antibody für ELISA, WB - ABIN560684
Seifert, Sellmann, Bloehdorn, Wein, Stilgenbauer, Dürig, Küppers: Cellular origin and pathophysiology of chronic lymphocytic leukemia. in The Journal of experimental medicine 2012
Show all 2 Pubmed References
Human Polyclonal EBF1 Primary Antibody für WB - ABIN515135
Lee, Xiao, Muench, Xiao, Fomin, Wiencke, Zheng, Dou, de Smith, Chokkalingam, Buffler, Ma, Wiemels: A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. in Nucleic acids research 2012
Human Monoclonal EBF1 Primary Antibody für RNAi, ELISA - ABIN560685
Zhang, Peng, Hu, Li, Sheng, Chen, Sullivan, Cerny, Hutchinson, Higgins, Miron, Zhang, Brehm, Li, Green, Li: The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. in Nature genetics 2012
Human Polyclonal EBF1 Primary Antibody für ELISA, WB - ABIN451729
Lagergren, Månsson, Zetterblad, Smith, Basta, Bryder, Akerblad, Sigvardsson: The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells. in The Journal of biological chemistry 2007
EBF1 heterozygosity resulted in the deregulation of at least eight transcription factors involved in lymphopoiesis and the deregulation of key proteins playing crucial roles in survival, development, and differentiation of pro-B lymphocytes.
Down-regulation of EBF1 (and EBF2 (zeige EBF2 Antikörper)) genes leads to a severe impairment of myelin formation in Schwann cells.
The authors show that transcription factors Lhx2 and Ebf specify olfactory receptor enhancers by binding in a functionally cooperative fashion to stereotypically spaced motifs that defy heterochromatin.
the interaction of the CCR4 (zeige CCR4 Antikörper)-NOT complex with EBF1 diversifies the function of EBF1 in a context-dependent manner and may coordinate transcriptional and post-transcriptional gene regulation.
Pax5 (zeige PAX5 Antikörper) and Ebf1 collaborate to modulate the transcriptional response to Notch (zeige NOTCH1 Antikörper) signaling, and their combined heterozygous loss allows for T-lineage conversion of B cell progenitors.
a dramatic increase in the frequency of pro-B cell leukemia was observed in mice with combined heterozygous mutations in the Ebf1 and Pax5 (zeige PAX5 Antikörper) genes, revealing a synergistic effect of combined dose reduction of these proteins
EBF1 is an important regulator of adipose morphology and fat cell lipolysis and may constitute a link between White adipose tissue inflammation, altered lipid metabolism, adipose hypertrophy, and insulin (zeige INS Antikörper) resistance.
Ebf1 has a significant and novel role in glomerular development, podocyte maturation, and the maintenance of kidney integrity and function.
Our results suggest that Bach2 (zeige BACH2 Antikörper) functions with Bach1 (zeige BACH1 Antikörper) and EBF1 to promote B cell development by repressing myeloid genes in common lymphoid progenitor cells
EBF1 functions as a key integrator of signal transduction, inflammation, and metabolism
EBF1 was down-regulated in cholangiocarcinoma (CCA (zeige FBN2 Antikörper)) tissues and cell lines.
Data show that GS Homeobox 2 (Gsx2 (zeige GSX2 Antikörper)) and Early B-cell factor 1 (Ebf1) combined overexpression in human embryonic stem (hES (zeige RRBP1 Antikörper)) cells achieves high yields of medium spiny neurons (MSNs).
this study demonstrates a role for the AHR (zeige AHR Antikörper) in regulating human B cell development, and it suggests that transcriptional alterations of EBF1 by the AHR (zeige AHR Antikörper) are involved in the underlying mechanism
In a Chinese population the TT genotype and T alleles in rs36071027 in the EBF1 gene are associated with an increased risk of coronary artery disease and its severity.
A genome-wide significant association was observed for rs35715456 (log10BF = 6.3) on chromosome 18 for the dichotomous trait of having at least one long-lived parent versus not having any long-lived parent. The most significant association among single nucleotide polymorphisms in longevity candidate genes (APOE (zeige APOE Antikörper), MINIPP1, FOXO3 (zeige FOXO3 Antikörper), EBF1, CAMKIV (zeige CAMK4 Antikörper), and OTOL1) was observed in the EBF1 gene region (rs17056207, p = .0002).
In this genomewide association study, we found that variants at the EBF1, EEFSEC (zeige EEFSEC Antikörper), AGTR2 (zeige AGTR2 Antikörper), WNT4 (zeige WNT4 Antikörper), ADCY5 (zeige ADCY5 Antikörper), and RAP2C (zeige RAP2C Antikörper) loci were associated with gestational duration and variants at the EBF1, EEFSEC (zeige EEFSEC Antikörper), and AGTR2 (zeige AGTR2 Antikörper) loci with preterm birth.
EBF1 polymorphism is associated with metabolic diseases.
Among 15 childhood ALL patients with EBF1-PDGFRB (zeige PDGFRB Antikörper) fusion proteins, the fusion arose from interstitial deletion of 5q33 (n = 11), balanced rearrangement (n = 2), or complex rearrangement (n = 2).
EBF1 is critical for transcriptional control of SLAMF1 (zeige SLAMF1 Antikörper) gene in human B cells.
two multi-zinc finger transcription cofactors named ZNF423 (zeige 104125 Antikörper) and ZNF521 (zeige ZNF521 Antikörper) have been characterised as potent inhibitors of EBF1 and are emerging as potentially relevant contributors to the development of B-cell leukaemias
Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
early B-cell factor 1
, transcription factor COE1-like
, transcription factor COE1
, Collier, Olf and EBF transcription factor 1
, olfactory neuronal transcription factor 1
, early B-cell factor (olfactory neuronal transcription factor 1)
, olfactory neuronal transcription factor
, early B-cell factor 1 protein