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The protein encoded by DNAJA2 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity.
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Human Monoclonal DNAJA2 Primary Antibody für IF, ELISA - ABIN564471
Rosales-Hernandez, Beck, Zhao, Braun, Braun: RDJ2 (DNAJA2) chaperones neural G protein signaling pathways. in Cell stress & chaperones 2008
Show all 3 Pubmed References
we combined the Hsp70 (zeige HSP70 Antikörper)-NEF pairs with cochaperones of the J protein family (DnaJA1 (zeige DNAJA1 Antikörper), DnaJA2, DnaJB1 (zeige DNAJB1 Antikörper), and DnaJB4 (zeige DNAJB4 Antikörper)) to generate 16 permutations.
The DNAJA2 substrate release mechanism is essential for chaperone-mediated folding.
Hsp40 (zeige DNAJB1 Antikörper) type 1 chaperones DJA1 (DNAJA1/Hdj2 (zeige DNAJA1 Antikörper)) and DJA2 (DNAJA2) as key modulators of hERG (zeige KCNH2 Antikörper) degradation
Rdj2 modulates G protein signaling and further suggest that chaperoning G proteins is an emerging theme of the J protein network.
Bag1 (zeige BAG1 Antikörper) NEF increased refolding by Hsc70 (zeige HSPA8 Antikörper) and DJA2, as did the newly characterized NEF Hsp110 (zeige HSPH1 Antikörper)
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus\; a glycine/phenylalanine (G/F)-rich region\; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
DnaJ (Hsp40) homolog, subfamily A, member 2
, DnaJ subfamily A member 2
, HIRA interacting protein 4
, HIRA-interacting protein 4
, cell cycle progression 3 protein
, cell cycle progression restoration gene 3 protein
, dnaJ homolog subfamily A member 2
, renal carcinoma antigen NY-REN-14
, DNA J protein